These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

440 related articles for article (PubMed ID: 15982878)

  • 1. Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1-phosphate and FTY720: discovery of potent S1P1 receptor agonists.
    Clemens JJ; Davis MD; Lynch KR; Macdonald TL
    Bioorg Med Chem Lett; 2005 Aug; 15(15):3568-72. PubMed ID: 15982878
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists.
    Clemens JJ; Davis MD; Lynch KR; Macdonald TL
    Bioorg Med Chem Lett; 2004 Oct; 14(19):4903-6. PubMed ID: 15341948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression.
    Krump-Konvalinkova V; Chwalla I; Siess W
    Biochem Biophys Res Commun; 2008 Jun; 370(4):603-8. PubMed ID: 18402775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.
    Forrest M; Sun SY; Hajdu R; Bergstrom J; Card D; Doherty G; Hale J; Keohane C; Meyers C; Milligan J; Mills S; Nomura N; Rosen H; Rosenbach M; Shei GJ; Singer II; Tian M; West S; White V; Xie J; Proia RL; Mandala S
    J Pharmacol Exp Ther; 2004 May; 309(2):758-68. PubMed ID: 14747617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FTY720 modulates human oligodendrocyte progenitor process extension and survival.
    Miron VE; Jung CG; Kim HJ; Kennedy TE; Soliven B; Antel JP
    Ann Neurol; 2008 Jan; 63(1):61-71. PubMed ID: 17918267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Attenuation of cell motility observed with high doses of sphingosine 1-phosphate or phosphorylated FTY720 involves RGS2 through its interactions with the receptor S1P.
    Kohno T; Igarashi Y
    Genes Cells; 2008 Jul; 13(7):747-57. PubMed ID: 18513330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720.
    Hale JJ; Neway W; Mills SG; Hajdu R; Ann Keohane C; Rosenbach M; Milligan J; Shei GJ; Chrebet G; Bergstrom J; Card D; Koo GC; Koprak SL; Jackson JJ; Rosen H; Mandala S
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3351-5. PubMed ID: 15149705
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.
    Vachal P; Toth LM; Hale JJ; Yan L; Mills SG; Chrebet GL; Koehane CA; Hajdu R; Milligan JA; Rosenbach MJ; Mandala S
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3684-7. PubMed ID: 16682185
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors.
    Chiba K
    Pharmacol Ther; 2005 Dec; 108(3):308-19. PubMed ID: 15951022
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1.
    Schmid G; Guba M; Ischenko I; Papyan A; Joka M; Schrepfer S; Bruns CJ; Jauch KW; Heeschen C; Graeb C
    J Cell Biochem; 2007 May; 101(1):259-70. PubMed ID: 17203465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. S1P receptor mediated activity of FTY720 phosphate mimics.
    Högenauer K; Hinterding K; Nussbaumer P
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1485-7. PubMed ID: 20153186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.
    Hale JJ; Yan L; Neway WE; Hajdu R; Bergstrom JD; Milligan JA; Shei GJ; Chrebet GL; Thornton RA; Card D; Rosenbach M; HughRosen ; Mandala S
    Bioorg Med Chem; 2004 Sep; 12(18):4803-7. PubMed ID: 15336258
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus.
    Chiba K; Matsuyuki H; Maeda Y; Sugahara K
    Cell Mol Immunol; 2006 Feb; 3(1):11-9. PubMed ID: 16549044
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets.
    Huwiler A; Pfeilschifter J
    Biochem Pharmacol; 2008 May; 75(10):1893-900. PubMed ID: 18321471
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate.
    Kiuchi M; Adachi K; Tomatsu A; Chino M; Takeda S; Tanaka Y; Maeda Y; Sato N; Mitsutomi N; Sugahara K; Chiba K
    Bioorg Med Chem; 2005 Jan; 13(2):425-32. PubMed ID: 15598563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator.
    Ter Braak M; Claas RF; Hegen B; Labocha S; Ferreirós N; Pfeilschifter J; Huwiler A; van Echten-Deckert G; Meyer Zu Heringdorf D
    Biochem Pharmacol; 2011 Mar; 81(5):617-25. PubMed ID: 21163254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology.
    Brinkmann V
    Pharmacol Ther; 2007 Jul; 115(1):84-105. PubMed ID: 17561264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine-1-phosphate and FTY720 as anti-atherosclerotic lipid compounds.
    Tölle M; Levkau B; Kleuser B; van der Giet M
    Eur J Clin Invest; 2007 Mar; 37(3):171-9. PubMed ID: 17359484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic sphingosine 1-phosphate receptor modulators--opportunities and potential pitfalls.
    Bolli MH; Lescop C; Nayler O
    Curr Top Med Chem; 2011; 11(6):726-57. PubMed ID: 21261590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neurological S1P signaling as an emerging mechanism of action of oral FTY720 (fingolimod) in multiple sclerosis.
    Lee CW; Choi JW; Chun J
    Arch Pharm Res; 2010 Oct; 33(10):1567-74. PubMed ID: 21052934
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.