These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
547 related articles for article (PubMed ID: 15986489)
1. Bcl-x(L) mediates increased production of humanized monoclonal antibodies in Chinese hamster ovary cells. Chiang GG; Sisk WP Biotechnol Bioeng; 2005 Sep; 91(7):779-92. PubMed ID: 15986489 [TBL] [Abstract][Full Text] [Related]
2. Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L). Majors BS; Betenbaugh MJ; Pederson NE; Chiang GG Biotechnol Bioeng; 2008 Oct; 101(3):567-78. PubMed ID: 18727128 [TBL] [Abstract][Full Text] [Related]
3. Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells. Majors BS; Betenbaugh MJ; Pederson NE; Chiang GG Biotechnol Prog; 2009; 25(4):1161-8. PubMed ID: 19551877 [TBL] [Abstract][Full Text] [Related]
4. Combining high-throughput screening of caspase activity with anti-apoptosis genes for development of robust CHO production cell lines. Dorai H; Ellis D; Keung YS; Campbell M; Zhuang M; Lin C; Betenbaugh MJ Biotechnol Prog; 2010; 26(5):1367-81. PubMed ID: 20945491 [TBL] [Abstract][Full Text] [Related]
5. Part I. Bcl-2 and Bcl-x(L) limit apoptosis upon infection with alphavirus vectors. Mastrangelo AJ; Hardwick JM; Bex F; Betenbaugh MJ Biotechnol Bioeng; 2000 Mar; 67(5):544-54. PubMed ID: 10649229 [TBL] [Abstract][Full Text] [Related]
6. Effect of Bcl-xL overexpression on apoptosis and autophagy in recombinant Chinese hamster ovary cells under nutrient-deprived condition. Kim YG; Kim JY; Mohan C; Lee GM Biotechnol Bioeng; 2009 Jul; 103(4):757-66. PubMed ID: 19266576 [TBL] [Abstract][Full Text] [Related]
7. Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Figueroa B; Chen S; Oyler GA; Hardwick JM; Betenbaugh MJ Biotechnol Bioeng; 2004 Mar; 85(6):589-600. PubMed ID: 14966800 [TBL] [Abstract][Full Text] [Related]
8. Control of culture environment for improved polyethylenimine-mediated transient production of recombinant monoclonal antibodies by CHO cells. Galbraith DJ; Tait AS; Racher AJ; Birch JR; James DC Biotechnol Prog; 2006; 22(3):753-62. PubMed ID: 16739959 [TBL] [Abstract][Full Text] [Related]
9. Enhanced human thrombopoietin production by sodium butyrate addition to serum-free suspension culture of bcl-2-overexpressing CHO cells. Sung YH; Lee GM Biotechnol Prog; 2005; 21(1):50-7. PubMed ID: 15903240 [TBL] [Abstract][Full Text] [Related]
10. A DIGE approach for the assessment of differential expression of the CHO proteome under sodium butyrate addition: Effect of Bcl-x(L) overexpression. Baik JY; Lee GM Biotechnol Bioeng; 2010 Feb; 105(2):358-67. PubMed ID: 19739093 [TBL] [Abstract][Full Text] [Related]
11. Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture. Nivitchanyong T; Martinez A; Ishaque A; Murphy JE; Konstantinov K; Betenbaugh MJ; Thrift J Biotechnol Bioeng; 2007 Nov; 98(4):825-41. PubMed ID: 17514750 [TBL] [Abstract][Full Text] [Related]
12. Bcl-x(L) overexpression delays the onset of autophagy and apoptosis in hyperosmotic recombinant Chinese hamster ovary cell cultures. Han YK; Ha TK; Kim YG; Lee GM J Biotechnol; 2011 Oct; 156(1):52-5. PubMed ID: 21875625 [TBL] [Abstract][Full Text] [Related]
13. Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors. Tan JG; Lee YY; Wang T; Yap MG; Tan TW; Ng SK Biotechnol J; 2015 May; 10(5):790-800. PubMed ID: 25740626 [TBL] [Abstract][Full Text] [Related]
14. A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells. Legmann R; Schreyer HB; Combs RG; McCormick EL; Russo AP; Rodgers ST Biotechnol Bioeng; 2009 Dec; 104(6):1107-20. PubMed ID: 19623562 [TBL] [Abstract][Full Text] [Related]
15. Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture. Dorai H; Kyung YS; Ellis D; Kinney C; Lin C; Jan D; Moore G; Betenbaugh MJ Biotechnol Bioeng; 2009 Jun; 103(3):592-608. PubMed ID: 19241388 [TBL] [Abstract][Full Text] [Related]
16. Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media. Meents H; Enenkel B; Eppenberger HM; Werner RG; Fussenegger M Biotechnol Bioeng; 2002 Dec; 80(6):706-16. PubMed ID: 12378612 [TBL] [Abstract][Full Text] [Related]
17. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins. Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683 [TBL] [Abstract][Full Text] [Related]
18. Overexpression of heat shock proteins (HSPs) in CHO cells for extended culture viability and improved recombinant protein production. Lee YY; Wong KT; Tan J; Toh PC; Mao Y; Brusic V; Yap MG J Biotechnol; 2009 Aug; 143(1):34-43. PubMed ID: 19527755 [TBL] [Abstract][Full Text] [Related]
19. The importance of Bcl-xL in the survival of human RPE cells. Zhang N; Peairs JJ; Yang P; Tyrrell J; Roberts J; Kole R; Jaffe GJ Invest Ophthalmol Vis Sci; 2007 Aug; 48(8):3846-53. PubMed ID: 17652760 [TBL] [Abstract][Full Text] [Related]
20. Process development for a recombinant Chinese hamster ovary (CHO) cell line utilizing a metal induced and amplified metallothionein expression system. Huang EP; Marquis CP; Gray PP Biotechnol Bioeng; 2004 Nov; 88(4):437-50. PubMed ID: 15459913 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]