BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1632 related articles for article (PubMed ID: 15987493)

  • 1. Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis.
    Yudoh K; Nakamura H; Masuko-Hongo K; Kato T; Nishioka K
    Arthritis Res Ther; 2005; 7(4):R904-14. PubMed ID: 15987493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis.
    Dai SM; Shan ZZ; Nakamura H; Masuko-Hongo K; Kato T; Nishioka K; Yudoh K
    Arthritis Rheum; 2006 Mar; 54(3):818-31. PubMed ID: 16508959
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function.
    Yudoh K; Nguyen vT; Nakamura H; Hongo-Masuko K; Kato T; Nishioka K
    Arthritis Res Ther; 2005; 7(2):R380-91. PubMed ID: 15743486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration during disease development.
    Yudoh K; Shishido K; Murayama H; Yano M; Matsubayashi K; Takada H; Nakamura H; Masuko K; Kato T; Nishioka K
    Arthritis Rheum; 2007 Oct; 56(10):3307-18. PubMed ID: 17907184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes.
    Coimbra IB; Jimenez SA; Hawkins DF; Piera-Velazquez S; Stokes DG
    Osteoarthritis Cartilage; 2004 Apr; 12(4):336-45. PubMed ID: 15023385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia and osteoarthritis: how chondrocytes survive hypoxic environments.
    Pfander D; Gelse K
    Curr Opin Rheumatol; 2007 Sep; 19(5):457-62. PubMed ID: 17762611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.
    Grimmer C; Pfander D; Swoboda B; Aigner T; Mueller L; Hennig FF; Gelse K
    Arthritis Rheum; 2007 Dec; 56(12):4084-94. PubMed ID: 18050215
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bone morphogenetic protein and transforming growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta.
    Kaiser M; Haag J; Söder S; Bau B; Aigner T
    Arthritis Rheum; 2004 Nov; 50(11):3535-40. PubMed ID: 15529348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the hypoxia-inducible factor-1 in overloaded temporomandibular joint, and induction of osteoclastogenesis.
    Shirakura M; Tanimoto K; Eguchi H; Miyauchi M; Nakamura H; Hiyama K; Tanimoto K; Tanaka E; Takata T; Tanne K
    Biochem Biophys Res Commun; 2010 Mar; 393(4):800-5. PubMed ID: 20171183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes.
    Afif H; Benderdour M; Mfuna-Endam L; Martel-Pelletier J; Pelletier JP; Duval N; Fahmi H
    Arthritis Res Ther; 2007; 9(2):R31. PubMed ID: 17386086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Enhanced expression of caveolin-1 in articular chondrocytes in osteoarthritis].
    Tang YQ; Shan ZZ; Dai SM
    Zhonghua Yi Xue Za Zhi; 2008 Jun; 88(21):1493-7. PubMed ID: 18953858
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor alpha suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis.
    Appleton CT; Usmani SE; Bernier SM; Aigner T; Beier F
    Arthritis Rheum; 2007 Nov; 56(11):3693-705. PubMed ID: 17968906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing.
    Yudoh K; Shi Y; Karasawa R
    Int J Rheum Dis; 2009 Jul; 12(2):90-9. PubMed ID: 20374325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1beta.
    Fan Z; Bau B; Yang H; Soeder S; Aigner T
    Arthritis Rheum; 2005 Jan; 52(1):136-43. PubMed ID: 15641077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of plasminogen activator inhibitor 1 expression in human osteoarthritic chondrocytes by fluid shear stress: role of protein kinase Calpha.
    Yeh CC; Chang HI; Chiang JK; Tsai WT; Chen LM; Wu CP; Chien S; Chen CN
    Arthritis Rheum; 2009 Aug; 60(8):2350-61. PubMed ID: 19644850
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dkk-1 promotes angiogenic responses and cartilage matrix proteinase secretion in synovial fibroblasts from osteoarthritic joints.
    Weng LH; Ko JY; Wang CJ; Sun YC; Wang FS
    Arthritis Rheum; 2012 Oct; 64(10):3267-77. PubMed ID: 22736200
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tetraspanin CD151 is expressed in osteoarthritic cartilage and is involved in pericellular activation of pro-matrix metalloproteinase 7 in osteoarthritic chondrocytes.
    Fujita Y; Shiomi T; Yanagimoto S; Matsumoto H; Toyama Y; Okada Y
    Arthritis Rheum; 2006 Oct; 54(10):3233-43. PubMed ID: 17009258
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of tenascin-C expression by tumor necrosis factor-alpha in cultured human osteoarthritis chondrocytes.
    Nakoshi Y; Hasegawa M; Sudo A; Yoshida T; Uchida A
    J Rheumatol; 2008 Jan; 35(1):147-52. PubMed ID: 18061975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIF-1α-induced HSP70 regulates anabolic responses in articular chondrocytes under hypoxic conditions.
    Tsuchida S; Arai Y; Takahashi KA; Kishida T; Terauchi R; Honjo K; Nakagawa S; Inoue H; Ikoma K; Ueshima K; Matsuki T; Mazda O; Kubo T
    J Orthop Res; 2014 Aug; 32(8):975-80. PubMed ID: 24677016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of cytokines in osteoarthritis pathophysiology.
    Fernandes JC; Martel-Pelletier J; Pelletier JP
    Biorheology; 2002; 39(1-2):237-46. PubMed ID: 12082286
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 82.