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3. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation. Wang J; Ouyang W; Li J; Wei L; Ma Q; Zhang Z; Tong Q; He J; Huang C Cancer Res; 2005 Aug; 65(15):6601-11. PubMed ID: 16061640 [TBL] [Abstract][Full Text] [Related]
4. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Weng LP; Smith WM; Dahia PL; Ziebold U; Gil E; Lees JA; Eng C Cancer Res; 1999 Nov; 59(22):5808-14. PubMed ID: 10582703 [TBL] [Abstract][Full Text] [Related]
5. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells. Choi Y; Zhang J; Murga C; Yu H; Koller E; Monia BP; Gutkind JS; Li W Oncogene; 2002 Aug; 21(34):5289-300. PubMed ID: 12149650 [TBL] [Abstract][Full Text] [Related]
6. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells. St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356 [TBL] [Abstract][Full Text] [Related]
7. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth. Edwards LA; Thiessen B; Dragowska WH; Daynard T; Bally MB; Dedhar S Oncogene; 2005 May; 24(22):3596-605. PubMed ID: 15782140 [TBL] [Abstract][Full Text] [Related]
8. PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. Wick W; Furnari FB; Naumann U; Cavenee WK; Weller M Oncogene; 1999 Jul; 18(27):3936-43. PubMed ID: 10435616 [TBL] [Abstract][Full Text] [Related]
9. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells. Kandasamy K; Srivastava RK Cancer Res; 2002 Sep; 62(17):4929-37. PubMed ID: 12208743 [TBL] [Abstract][Full Text] [Related]
10. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein. Paramio JM; Navarro M; Segrelles C; Gómez-Casero E; Jorcano JL Oncogene; 1999 Dec; 18(52):7462-8. PubMed ID: 10602505 [TBL] [Abstract][Full Text] [Related]
11. Enhanced protein kinase B/Akt signalling in pituitary tumours. Musat M; Korbonits M; Kola B; Borboli N; Hanson MR; Nanzer AM; Grigson J; Jordan S; Morris DG; Gueorguiev M; Coculescu M; Basu S; Grossman AB Endocr Relat Cancer; 2005 Jun; 12(2):423-33. PubMed ID: 15947113 [TBL] [Abstract][Full Text] [Related]
12. PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. Wan X; Yokoyama Y; Shinohara A; Takahashi Y; Tamaya T Cell Death Differ; 2002 Apr; 9(4):414-20. PubMed ID: 11965494 [TBL] [Abstract][Full Text] [Related]
13. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Ramaswamy S; Nakamura N; Vazquez F; Batt DB; Perera S; Roberts TM; Sellers WR Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2110-5. PubMed ID: 10051603 [TBL] [Abstract][Full Text] [Related]
14. Hyaluronic acid induces osteopontin via the phosphatidylinositol 3-kinase/Akt pathway to enhance the motility of human glioma cells. Kim MS; Park MJ; Moon EJ; Kim SJ; Lee CH; Yoo H; Shin SH; Song ES; Lee SH Cancer Res; 2005 Feb; 65(3):686-91. PubMed ID: 15705860 [TBL] [Abstract][Full Text] [Related]
15. Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo. Saito Y; Swanson X; Mhashilkar AM; Oida Y; Schrock R; Branch CD; Chada S; Zumstein L; Ramesh R Gene Ther; 2003 Nov; 10(23):1961-9. PubMed ID: 14528320 [TBL] [Abstract][Full Text] [Related]
16. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Haas-Kogan D; Shalev N; Wong M; Mills G; Yount G; Stokoe D Curr Biol; 1998 Oct; 8(21):1195-8. PubMed ID: 9799739 [TBL] [Abstract][Full Text] [Related]
17. Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779. Shi Y; Gera J; Hu L; Hsu JH; Bookstein R; Li W; Lichtenstein A Cancer Res; 2002 Sep; 62(17):5027-34. PubMed ID: 12208757 [TBL] [Abstract][Full Text] [Related]