BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 15994303)

  • 1. Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity.
    Regala RP; Weems C; Jamieson L; Copland JA; Thompson EA; Fields AP
    J Biol Chem; 2005 Sep; 280(35):31109-15. PubMed ID: 15994303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation.
    Justilien V; Fields AP
    Oncogene; 2009 Oct; 28(41):3597-607. PubMed ID: 19617897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells.
    Stallings-Mann M; Jamieson L; Regala RP; Weems C; Murray NR; Fields AP
    Cancer Res; 2006 Feb; 66(3):1767-74. PubMed ID: 16452237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer.
    Fields AP; Frederick LA; Regala RP
    Biochem Soc Trans; 2007 Nov; 35(Pt 5):996-1000. PubMed ID: 17956262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis.
    Scotti ML; Bamlet WR; Smyrk TC; Fields AP; Murray NR
    Cancer Res; 2010 Mar; 70(5):2064-74. PubMed ID: 20179210
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer.
    Frederick LA; Matthews JA; Jamieson L; Justilien V; Thompson EA; Radisky DC; Fields AP
    Oncogene; 2008 Aug; 27(35):4841-53. PubMed ID: 18427549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer.
    Regala RP; Weems C; Jamieson L; Khoor A; Edell ES; Lohse CM; Fields AP
    Cancer Res; 2005 Oct; 65(19):8905-11. PubMed ID: 16204062
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic activity of Ect2 is regulated through protein kinase C iota-mediated phosphorylation.
    Justilien V; Jameison L; Der CJ; Rossman KL; Fields AP
    J Biol Chem; 2011 Mar; 286(10):8149-8157. PubMed ID: 21189248
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
    Murray NR; Jamieson L; Yu W; Zhang J; Gökmen-Polar Y; Sier D; Anastasiadis P; Gatalica Z; Thompson EA; Fields AP
    J Cell Biol; 2004 Mar; 164(6):797-802. PubMed ID: 15024028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota.
    Erdogan E; Lamark T; Stallings-Mann M; Lee Jamieson ; Pellecchia M; Thompson EA; Johansen T; Fields AP
    J Biol Chem; 2006 Sep; 281(38):28450-9. PubMed ID: 16861740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Atypical protein kinase Cι (PKCι) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCι-SKP2-AKT pathway.
    Liu SG; Wang BS; Jiang YY; Zhang TT; Shi ZZ; Yang Y; Yang YL; Wang XC; Lin DC; Zhang Y; Yang H; Cai Y; Zhan QM; Wang MR
    Mol Cancer Res; 2011 Apr; 9(4):390-402. PubMed ID: 21310827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion.
    Butler AM; Scotti Buzhardt ML; Erdogan E; Li S; Inman KS; Fields AP; Murray NR
    Oncotarget; 2015 Jun; 6(17):15297-310. PubMed ID: 25915428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis.
    Wang Y; Justilien V; Brennan KI; Jamieson L; Murray NR; Fields AP
    Oncogene; 2017 Jan; 36(4):534-545. PubMed ID: 27321186
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma.
    Kim KH; Chung C; Kim JM; Lee D; Cho SY; Lee TH; Cho HJ; Yeo MK
    BMC Cancer; 2019 Aug; 19(1):804. PubMed ID: 31412817
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
    Yin N; Liu Y; Khoor A; Wang X; Thompson EA; Leitges M; Justilien V; Weems C; Murray NR; Fields AP
    Cancer Cell; 2019 Aug; 36(2):156-167.e7. PubMed ID: 31378680
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells.
    Justilien V; Lewis KC; Meneses KM; Jamieson L; Murray NR; Fields AP
    J Biol Chem; 2020 Jun; 295(24):8214-8226. PubMed ID: 32350115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKCι maintains a tumor-initiating cell phenotype that is required for ovarian tumorigenesis.
    Wang Y; Hill KS; Fields AP
    Mol Cancer Res; 2013 Dec; 11(12):1624-35. PubMed ID: 24174471
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis.
    Regala RP; Davis RK; Kunz A; Khoor A; Leitges M; Fields AP
    Cancer Res; 2009 Oct; 69(19):7603-11. PubMed ID: 19738040
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade.
    Apostolatos AH; Ratnayake WS; Win-Piazza H; Apostolatos CA; Smalley T; Kang L; Salup R; Hill R; Acevedo-Duncan M
    Int J Oncol; 2018 Nov; 53(5):1836-1846. PubMed ID: 30226591
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinoma.
    Erdogan E; Klee EW; Thompson EA; Fields AP
    Clin Cancer Res; 2009 Mar; 15(5):1527-33. PubMed ID: 19223491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.