These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 15994758)

  • 1. Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.
    Ueda K; Kawano J; Takeda K; Yujiri T; Tanabe K; Anno T; Akiyama M; Nozaki J; Yoshinaga T; Koizumi A; Shinoda K; Oka Y; Tanizawa Y
    Eur J Endocrinol; 2005 Jul; 153(1):167-76. PubMed ID: 15994758
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
    Yamada T; Ishihara H; Tamura A; Takahashi R; Yamaguchi S; Takei D; Tokita A; Satake C; Tashiro F; Katagiri H; Aburatani H; Miyazaki J; Oka Y
    Hum Mol Genet; 2006 May; 15(10):1600-9. PubMed ID: 16571599
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.
    Yamaguchi S; Ishihara H; Tamura A; Yamada T; Takahashi R; Takei D; Katagiri H; Oka Y
    Biochem Biophys Res Commun; 2004 Dec; 325(1):250-6. PubMed ID: 15522226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
    Riggs AC; Bernal-Mizrachi E; Ohsugi M; Wasson J; Fatrai S; Welling C; Murray J; Schmidt RE; Herrera PL; Permutt MA
    Diabetologia; 2005 Nov; 48(11):2313-21. PubMed ID: 16215705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HDLs protect the MIN6 insulinoma cell line against tunicamycin-induced apoptosis without inhibiting ER stress and without restoring ER functionality.
    Puyal J; Pétremand J; Dubuis G; Rummel C; Widmann C
    Mol Cell Endocrinol; 2013 Dec; 381(1-2):291-301. PubMed ID: 23994023
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel heterozygous mutation of the WFS1 gene leading to constitutive endoplasmic reticulum stress is the cause of Wolfram syndrome.
    Morikawa S; Tajima T; Nakamura A; Ishizu K; Ariga T
    Pediatr Diabetes; 2017 Dec; 18(8):934-941. PubMed ID: 28271591
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis.
    Horke S; Witte I; Wilgenbus P; Altenhöfer S; Krüger M; Li H; Förstermann U
    Biochem J; 2008 Dec; 416(3):395-405. PubMed ID: 18691157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.
    Nozaki Ji; Kubota H; Yoshida H; Naitoh M; Goji J; Yoshinaga T; Mori K; Koizumi A; Nagata K
    Genes Cells; 2004 Mar; 9(3):261-70. PubMed ID: 15005713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
    Philbrook C; Fritz E; Weiher H
    Exp Gerontol; 2005; 40(8-9):671-8. PubMed ID: 16087305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells.
    Hatanaka M; Tanabe K; Yanai A; Ohta Y; Kondo M; Akiyama M; Shinoda K; Oka Y; Tanizawa Y
    Hum Mol Genet; 2011 Apr; 20(7):1274-84. PubMed ID: 21199859
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells.
    Srinivasan S; Ohsugi M; Liu Z; Fatrai S; Bernal-Mizrachi E; Permutt MA
    Diabetes; 2005 Apr; 54(4):968-75. PubMed ID: 15793234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells.
    Odisho T; Zhang L; Volchuk A
    Exp Cell Res; 2015 Jan; 330(1):111-22. PubMed ID: 25447309
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wolfram syndrome and WFS1 gene.
    Rigoli L; Lombardo F; Di Bella C
    Clin Genet; 2011 Feb; 79(2):103-17. PubMed ID: 20738327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.
    Kondo M; Tanabe K; Amo-Shiinoki K; Hatanaka M; Morii T; Takahashi H; Seino S; Yamada Y; Tanizawa Y
    Diabetologia; 2018 Oct; 61(10):2189-2201. PubMed ID: 30054673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased insulin demand promotes while pioglitazone prevents pancreatic beta cell apoptosis in Wfs1 knockout mice.
    Akiyama M; Hatanaka M; Ohta Y; Ueda K; Yanai A; Uehara Y; Tanabe K; Tsuru M; Miyazaki M; Saeki S; Saito T; Shinoda K; Oka Y; Tanizawa Y
    Diabetologia; 2009 Apr; 52(4):653-63. PubMed ID: 19190890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.
    Fonseca SG; Fukuma M; Lipson KL; Nguyen LX; Allen JR; Oka Y; Urano F
    J Biol Chem; 2005 Nov; 280(47):39609-15. PubMed ID: 16195229
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of 4-phenylbutyrate and valproate on dominant mutations of WFS1 gene in Wolfram syndrome.
    Batjargal K; Tajima T; Jimbo EF; Yamagata T
    J Endocrinol Invest; 2020 Sep; 43(9):1317-1325. PubMed ID: 32219690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.
    Lai E; Bikopoulos G; Wheeler MB; Rozakis-Adcock M; Volchuk A
    Am J Physiol Endocrinol Metab; 2008 Mar; 294(3):E540-50. PubMed ID: 18198352
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
    Morikawa S; Blacher L; Onwumere C; Urano F
    Front Endocrinol (Lausanne); 2022; 13():849204. PubMed ID: 35399956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.
    Yamaguchi S; Ishihara H; Yamada T; Tamura A; Usui M; Tominaga R; Munakata Y; Satake C; Katagiri H; Tashiro F; Aburatani H; Tsukiyama-Kohara K; Miyazaki J; Sonenberg N; Oka Y
    Cell Metab; 2008 Mar; 7(3):269-76. PubMed ID: 18316032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.