BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 16000301)

  • 1. Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase.
    Zang H; Fang Q; Pegg AE; Guengerich FP
    J Biol Chem; 2005 Sep; 280(35):30873-81. PubMed ID: 16000301
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts.
    Lukash LL; Boldt J; Pegg AE; Dolan ME; Maher VM; McCormick JJ
    Mutat Res; 1991; 250(1-2):397-409. PubMed ID: 1944354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
    Goodtzova K; Kanugula S; Edara S; Pegg AE
    Biochemistry; 1998 Sep; 37(36):12489-95. PubMed ID: 9730821
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mass spectrometry based approach to study the kinetics of O6-alkylguanine DNA alkyltransferase-mediated repair of O6-pyridyloxobutyl-2'-deoxyguanosine adducts in DNA.
    Kotandeniya D; Murphy D; Seneviratne U; Guza R; Pegg A; Kanugula S; Tretyakova N
    Chem Res Toxicol; 2011 Nov; 24(11):1966-75. PubMed ID: 21913712
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reaction and binding of oligodeoxynucleotides containing analogues of O6-methylguanine with wild-type and mutant human O6-alkylguanine-DNA alkyltransferase.
    Spratt TE; Wu JD; Levy DE; Kanugula S; Pegg AE
    Biochemistry; 1999 May; 38(21):6801-6. PubMed ID: 10346901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reaction of O6-benzylguanine-resistant mutants of human O6-alkylguanine-DNA alkyltransferase with O6-benzylguanine in oligodeoxyribonucleotides.
    Pegg AE; Kanugula S; Edara S; Pauly GT; Moschel RC; Goodtzova K
    J Biol Chem; 1998 May; 273(18):10863-7. PubMed ID: 9556560
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS; Thomson NM; Fleischer NL; Pauly GT; Moschel RC; Kanugula S; Fang Q; Pegg AE; Peterson LA
    Chem Res Toxicol; 2004 Mar; 17(3):424-34. PubMed ID: 15025514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methyl DNA adducts, DNA repair, and hypoxanthine-guanine phosphoribosyl transferase mutations in peripheral white blood cells from patients with malignant melanoma treated with dacarbazine and hydroxyurea.
    Philip PA; Souliotis VL; Harris AL; Salisbury A; Tates AD; Mitchell K; van Delft JH; Ganesan TS; Kyrtopoulos SA
    Clin Cancer Res; 1996 Feb; 2(2):303-10. PubMed ID: 9816173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. O6-alkylguanine-DNA alkyltransferases repair O6-methylguanine in DNA with Michaelis-Menten-like kinetics.
    Meyer AS; McCain MD; Fang Q; Pegg AE; Spratt TE
    Chem Res Toxicol; 2003 Nov; 16(11):1405-9. PubMed ID: 14615965
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutagenicity associated with O6-methylguanine-DNA damage and mechanism of nucleotide flipping by AGT during repair.
    Jena NR; Bansal M
    Phys Biol; 2011 Aug; 8(4):046007. PubMed ID: 21666294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differences in the rate of repair of O6-alkylguanines in different sequence contexts by O6-alkylguanine-DNA alkyltransferase.
    Coulter R; Blandino M; Tomlinson JM; Pauly GT; Krajewska M; Moschel RC; Peterson LA; Pegg AE; Spratt TE
    Chem Res Toxicol; 2007 Dec; 20(12):1966-71. PubMed ID: 17975884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinetics of O(6)-pyridyloxobutyl-2'-deoxyguanosine repair by human O(6)-alkylguanine DNA alkyltransferase.
    Kotandeniya D; Murphy D; Yan S; Park S; Seneviratne U; Koopmeiners JS; Pegg A; Kanugula S; Kassie F; Tretyakova N
    Biochemistry; 2013 Jun; 52(23):4075-88. PubMed ID: 23683164
    [TBL] [Abstract][Full Text] [Related]  

  • 13. O6-Alkylguanine-DNA alkyltransferase: influence on susceptibility to the genetic effects of alkylating agents.
    Kyrtopoulos SA
    Toxicol Lett; 1998 Dec; 102-103():53-7. PubMed ID: 10022232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy.
    Tubbs JL; Pegg AE; Tainer JA
    DNA Repair (Amst); 2007 Aug; 6(8):1100-15. PubMed ID: 17485252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repair of oligodeoxynucleotides containing O6-methylguanine by O6-alkylguanine-DNA-alkyltransferase.
    Scicchitano D; Jones RA; Kuzmich S; Gaffney B; Lasko DD; Essigmann JM; Pegg AE
    Carcinogenesis; 1986 Aug; 7(8):1383-6. PubMed ID: 3731392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Function of domains of human O6-alkylguanine-DNA alkyltransferase.
    Fang Q; Kanugula S; Pegg AE
    Biochemistry; 2005 Nov; 44(46):15396-405. PubMed ID: 16285744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetics of O(6)-methyl-2'-deoxyguanosine repair by O(6)-alkylguanine DNA alkyltransferase within K-ras gene-derived DNA sequences.
    Guza R; Rajesh M; Fang Q; Pegg AE; Tretyakova N
    Chem Res Toxicol; 2006 Apr; 19(4):531-8. PubMed ID: 16608164
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
    Souliotis VL; Kyrtopoulos SA
    Cancer Res; 1989 Dec; 49(24 Pt 1):6997-7001. PubMed ID: 2684406
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assay by inhibition of repair to measure O6-methylguanine in DNA.
    Mironov NM; Martel-Planche G; Wild CP
    Environ Mol Mutagen; 1994; 23(2):110-5. PubMed ID: 8143697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.
    Moser AM; Patel M; Yoo H; Balis FM; Hawkins ME
    Anal Biochem; 2000 Jun; 281(2):216-22. PubMed ID: 10870838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.