BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 16000307)

  • 1. Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
    Sommer U; Schmid C; Sobota RM; Lehmann U; Stevenson NJ; Johnston JA; Schaper F; Heinrich PC; Haan S
    J Biol Chem; 2005 Sep; 280(36):31478-88. PubMed ID: 16000307
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
    Lehmann U; Schmitz J; Weissenbach M; Sobota RM; Hortner M; Friederichs K; Behrmann I; Tsiaris W; Sasaki A; Schneider-Mergener J; Yoshimura A; Neel BG; Heinrich PC; Schaper F
    J Biol Chem; 2003 Jan; 278(1):661-71. PubMed ID: 12403768
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.
    Schmitz J; Weissenbach M; Haan S; Heinrich PC; Schaper F
    J Biol Chem; 2000 Apr; 275(17):12848-56. PubMed ID: 10777583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling.
    Fischer P; Lehmann U; Sobota RM; Schmitz J; Niemand C; Linnemann S; Haan S; Behrmann I; Yoshimura A; Johnston JA; Müller-Newen G; Heinrich PC; Schaper F
    Biochem J; 2004 Mar; 378(Pt 2):449-60. PubMed ID: 14611646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.
    Fairlie WD; De Souza D; Nicola NA; Baca M
    Biochem J; 2003 Jun; 372(Pt 2):495-502. PubMed ID: 12593670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oncostatin M receptor-mediated signal transduction is negatively regulated by SOCS3 through a receptor tyrosine-independent mechanism.
    Stross C; Radtke S; Clahsen T; Gerlach C; Volkmer-Engert R; Schaper F; Heinrich PC; Hermanns HM
    J Biol Chem; 2006 Mar; 281(13):8458-68. PubMed ID: 16459330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SOCS3 regulates the plasticity of gp130 signaling.
    Lang R; Pauleau AL; Parganas E; Takahashi Y; Mages J; Ihle JN; Rutschman R; Murray PJ
    Nat Immunol; 2003 Jun; 4(6):546-50. PubMed ID: 12754506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Desensitization of signaling by oncostatin M in human vascular cells involves cytoplasmic Tyr residue 759 in gp130 but is not mediated by either Src homology 2 domain-containing tyrosine phosphatase 2 or suppressor of cytokine signaling 3.
    Mahboubi K; Kirkiles-Smith NC; Karras J; Pober JS
    J Biol Chem; 2003 Jul; 278(27):25014-23. PubMed ID: 12724316
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy.
    Podewski EK; Hilfiker-Kleiner D; Hilfiker A; Morawietz H; Lichtenberg A; Wollert KC; Drexler H
    Circulation; 2003 Feb; 107(6):798-802. PubMed ID: 12591746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases.
    Liu Y; Karaca M; Zhang Z; Gioeli D; Earp HS; Whang YE
    Oncogene; 2010 Jun; 29(22):3208-16. PubMed ID: 20383201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
    Anhuf D; Weissenbach M; Schmitz J; Sobota R; Hermanns HM; Radtke S; Linnemann S; Behrmann I; Heinrich PC; Schaper F
    J Immunol; 2000 Sep; 165(5):2535-43. PubMed ID: 10946280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase.
    Peraldi P; Filloux C; Emanuelli B; Hilton DJ; Van Obberghen E
    J Biol Chem; 2001 Jul; 276(27):24614-20. PubMed ID: 11325969
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A family of cytokine-inducible inhibitors of signalling.
    Starr R; Willson TA; Viney EM; Murray LJ; Rayner JR; Jenkins BJ; Gonda TJ; Alexander WS; Metcalf D; Nicola NA; Hilton DJ
    Nature; 1997 Jun; 387(6636):917-21. PubMed ID: 9202125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L; Maassen BG; Radtke S; Behrmann I; Schaper F; Heinrich PC; Graeve L; Gatsios P
    FEBS Lett; 2000 Jul; 478(1-2):100-4. PubMed ID: 10922477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
    Heinrich PC; Behrmann I; Müller-Newen G; Schaper F; Graeve L
    Biochem J; 1998 Sep; 334 ( Pt 2)(Pt 2):297-314. PubMed ID: 9716487
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production.
    Matsumoto A; Seki Y; Watanabe R; Hayashi K; Johnston JA; Harada Y; Abe R; Yoshimura A; Kubo M
    J Exp Med; 2003 Feb; 197(4):425-36. PubMed ID: 12591901
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130.
    Nicholson SE; De Souza D; Fabri LJ; Corbin J; Willson TA; Zhang JG; Silva A; Asimakis M; Farley A; Nash AD; Metcalf D; Hilton DJ; Nicola NA; Baca M
    Proc Natl Acad Sci U S A; 2000 Jun; 97(12):6493-8. PubMed ID: 10829066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and function of a new STAT-induced STAT inhibitor.
    Naka T; Narazaki M; Hirata M; Matsumoto T; Minamoto S; Aono A; Nishimoto N; Kajita T; Taga T; Yoshizaki K; Akira S; Kishimoto T
    Nature; 1997 Jun; 387(6636):924-9. PubMed ID: 9202127
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.