201 related articles for article (PubMed ID: 16000321)
1. Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.
Wang J; Xu G; Li H; Gonzales V; Fromholt D; Karch C; Copeland NG; Jenkins NA; Borchelt DR
Hum Mol Genet; 2005 Aug; 14(16):2335-47. PubMed ID: 16000321
[TBL] [Abstract][Full Text] [Related]
2. Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation.
Xu G; Fromholt S; Ayers JI; Brown H; Siemienski Z; Crosby KW; Mayer CA; Janus C; Borchelt DR
J Neurochem; 2015 May; 133(3):452-64. PubMed ID: 25557022
[TBL] [Abstract][Full Text] [Related]
3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
4. Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis.
Stieber A; Gonatas JO; Gonatas NK
J Neurol Sci; 2000 Aug; 177(2):114-23. PubMed ID: 10980307
[TBL] [Abstract][Full Text] [Related]
5. An examination of alpha B-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis.
Karch CM; Borchelt DR
J Neurochem; 2010 Jun; 113(5):1092-100. PubMed ID: 20067574
[TBL] [Abstract][Full Text] [Related]
6. Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model.
Tateno M; Sadakata H; Tanaka M; Itohara S; Shin RM; Miura M; Masuda M; Aosaki T; Urushitani M; Misawa H; Takahashi R
Hum Mol Genet; 2004 Oct; 13(19):2183-96. PubMed ID: 15294873
[TBL] [Abstract][Full Text] [Related]
7. Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.
Ayers JI; Fromholt SE; O'Neal VM; Diamond JH; Borchelt DR
Acta Neuropathol; 2016 Jan; 131(1):103-14. PubMed ID: 26650262
[TBL] [Abstract][Full Text] [Related]
8. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
Urushitani M; Kurisu J; Tsukita K; Takahashi R
J Neurochem; 2002 Dec; 83(5):1030-42. PubMed ID: 12437574
[TBL] [Abstract][Full Text] [Related]
9. Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.
Wang J; Slunt H; Gonzales V; Fromholt D; Coonfield M; Copeland NG; Jenkins NA; Borchelt DR
Hum Mol Genet; 2003 Nov; 12(21):2753-64. PubMed ID: 12966034
[TBL] [Abstract][Full Text] [Related]
10. Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice.
Jaarsma D; Teuling E; Haasdijk ED; De Zeeuw CI; Hoogenraad CC
J Neurosci; 2008 Feb; 28(9):2075-88. PubMed ID: 18305242
[TBL] [Abstract][Full Text] [Related]
11. Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification.
Watanabe Y; Yasui K; Nakano T; Doi K; Fukada Y; Kitayama M; Ishimoto M; Kurihara S; Kawashima M; Fukuda H; Adachi Y; Inoue T; Nakashima K
Brain Res Mol Brain Res; 2005 Apr; 135(1-2):12-20. PubMed ID: 15857664
[TBL] [Abstract][Full Text] [Related]
12. The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Crippa V; Sau D; Rusmini P; Boncoraglio A; Onesto E; Bolzoni E; Galbiati M; Fontana E; Marino M; Carra S; Bendotti C; De Biasi S; Poletti A
Hum Mol Genet; 2010 Sep; 19(17):3440-56. PubMed ID: 20570967
[TBL] [Abstract][Full Text] [Related]
13. Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice.
Zetterström P; Graffmo KS; Andersen PM; Brännström T; Marklund SL
J Biol Chem; 2011 Jun; 286(23):20130-6. PubMed ID: 21493711
[TBL] [Abstract][Full Text] [Related]
14. Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
Turner BJ; Lopes EC; Cheema SS
J Cell Biochem; 2004 Apr; 91(5):1074-84. PubMed ID: 15034941
[TBL] [Abstract][Full Text] [Related]
15. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.
Pardo CA; Xu Z; Borchelt DR; Price DL; Sisodia SS; Cleveland DW
Proc Natl Acad Sci U S A; 1995 Feb; 92(4):954-8. PubMed ID: 7862672
[TBL] [Abstract][Full Text] [Related]
16. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice.
Borchelt DR; Wong PC; Becher MW; Pardo CA; Lee MK; Xu ZS; Thinakaran G; Jenkins NA; Copeland NG; Sisodia SS; Cleveland DW; Price DL; Hoffman PN
Neurobiol Dis; 1998 Jul; 5(1):27-35. PubMed ID: 9702785
[TBL] [Abstract][Full Text] [Related]
17. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
Clement AM; Nguyen MD; Roberts EA; Garcia ML; Boillée S; Rule M; McMahon AP; Doucette W; Siwek D; Ferrante RJ; Brown RH; Julien JP; Goldstein LS; Cleveland DW
Science; 2003 Oct; 302(5642):113-7. PubMed ID: 14526083
[TBL] [Abstract][Full Text] [Related]
18. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
[TBL] [Abstract][Full Text] [Related]
19. Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1.
Oono M; Okado-Matsumoto A; Shodai A; Ido A; Ohta Y; Abe K; Ayaki T; Ito H; Takahashi R; Taniguchi N; Urushitani M
J Neurochem; 2014 Feb; 128(3):403-18. PubMed ID: 24032595
[TBL] [Abstract][Full Text] [Related]
20. Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.
Jonsson PA; Ernhill K; Andersen PM; Bergemalm D; Brännström T; Gredal O; Nilsson P; Marklund SL
Brain; 2004 Jan; 127(Pt 1):73-88. PubMed ID: 14534160
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
