173 related articles for article (PubMed ID: 16002779)
1. Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice.
Jonker JW; Freeman J; Bolscher E; Musters S; Alvi AJ; Titley I; Schinkel AH; Dale TC
Stem Cells; 2005 Sep; 23(8):1059-65. PubMed ID: 16002779
[TBL] [Abstract][Full Text] [Related]
2. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo.
Zhou S; Morris JJ; Barnes Y; Lan L; Schuetz JD; Sorrentino BP
Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12339-44. PubMed ID: 12218177
[TBL] [Abstract][Full Text] [Related]
3. Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone.
Zhou S; Zong Y; Lu T; Sorrentino BP
Biotechniques; 2003 Dec; 35(6):1248-52. PubMed ID: 14682060
[TBL] [Abstract][Full Text] [Related]
4. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.
Durmus S; Xu N; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
Pharmacol Res; 2013 Oct; 76():9-16. PubMed ID: 23827160
[TBL] [Abstract][Full Text] [Related]
5. Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype.
Yamamoto K; Suzu S; Yoshidomi Y; Hiyoshi M; Harada H; Okada S
Immunol Lett; 2007 Nov; 114(1):52-8. PubMed ID: 17905444
[TBL] [Abstract][Full Text] [Related]
6. Role of P-glycoprotein on the brain penetration and brain pharmacodynamic activity of the MEK inhibitor cobimetinib.
Choo EF; Ly J; Chan J; Shahidi-Latham SK; Messick K; Plise E; Quiason CM; Yang L
Mol Pharm; 2014 Nov; 11(11):4199-207. PubMed ID: 25243894
[TBL] [Abstract][Full Text] [Related]
7. P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecan.
de Vries NA; Zhao J; Kroon E; Buckle T; Beijnen JH; van Tellingen O
Clin Cancer Res; 2007 Nov; 13(21):6440-9. PubMed ID: 17975156
[TBL] [Abstract][Full Text] [Related]
8. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.
Kim M; Turnquist H; Jackson J; Sgagias M; Yan Y; Gong M; Dean M; Sharp JG; Cowan K
Clin Cancer Res; 2002 Jan; 8(1):22-8. PubMed ID: 11801536
[TBL] [Abstract][Full Text] [Related]
9. Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.
Vlaming ML; Teunissen SF; van de Steeg E; van Esch A; Wagenaar E; Brunsveld L; de Greef TF; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
Mol Pharmacol; 2014 Mar; 85(3):520-30. PubMed ID: 24334255
[TBL] [Abstract][Full Text] [Related]
10. Akt signaling regulates side population cell phenotype via Bcrp1 translocation.
Mogi M; Yang J; Lambert JF; Colvin GA; Shiojima I; Skurk C; Summer R; Fine A; Quesenberry PJ; Walsh K
J Biol Chem; 2003 Oct; 278(40):39068-75. PubMed ID: 12851395
[TBL] [Abstract][Full Text] [Related]
11. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype.
Zhou S; Schuetz JD; Bunting KD; Colapietro AM; Sampath J; Morris JJ; Lagutina I; Grosveld GC; Osawa M; Nakauchi H; Sorrentino BP
Nat Med; 2001 Sep; 7(9):1028-34. PubMed ID: 11533706
[TBL] [Abstract][Full Text] [Related]
12. Use of the cassette-dosing approach to assess brain penetration in drug discovery.
Liu X; Ding X; Deshmukh G; Liederer BM; Hop CE
Drug Metab Dispos; 2012 May; 40(5):963-9. PubMed ID: 22328585
[TBL] [Abstract][Full Text] [Related]
13. Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells.
Uchida N; Leung FY; Eaves CJ
Exp Hematol; 2002 Aug; 30(8):862-9. PubMed ID: 12160837
[TBL] [Abstract][Full Text] [Related]
14. Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1.
Shimano K; Satake M; Okaya A; Kitanaka J; Kitanaka N; Takemura M; Sakagami M; Terada N; Tsujimura T
Am J Pathol; 2003 Jul; 163(1):3-9. PubMed ID: 12819005
[TBL] [Abstract][Full Text] [Related]
15. Compartment-specific roles of ATP-binding cassette transporters define differential topotecan distribution in brain parenchyma and cerebrospinal fluid.
Shen J; Carcaboso AM; Hubbard KE; Tagen M; Wynn HG; Panetta JC; Waters CM; Elmeliegy MA; Stewart CF
Cancer Res; 2009 Jul; 69(14):5885-92. PubMed ID: 19567673
[TBL] [Abstract][Full Text] [Related]
16. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice.
Zhou L; Schmidt K; Nelson FR; Zelesky V; Troutman MD; Feng B
Drug Metab Dispos; 2009 May; 37(5):946-55. PubMed ID: 19225039
[TBL] [Abstract][Full Text] [Related]
17. Role of P-glycoprotein and breast cancer resistance protein-1 in the brain penetration and brain pharmacodynamic activity of the novel phosphatidylinositol 3-kinase inhibitor GDC-0941.
Salphati L; Lee LB; Pang J; Plise EG; Zhang X
Drug Metab Dispos; 2010 Sep; 38(9):1422-6. PubMed ID: 20522663
[TBL] [Abstract][Full Text] [Related]
18. Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib.
Tang SC; de Vries N; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
J Pharmacol Exp Ther; 2013 Sep; 346(3):486-94. PubMed ID: 23843632
[TBL] [Abstract][Full Text] [Related]
19. Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells.
Budak MT; Alpdogan OS; Zhou M; Lavker RM; Akinci MA; Wolosin JM
J Cell Sci; 2005 Apr; 118(Pt 8):1715-24. PubMed ID: 15811951
[TBL] [Abstract][Full Text] [Related]
20. 'Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells.
Lassalle B; Bastos H; Louis JP; Riou L; Testart J; Dutrillaux B; Fouchet P; Allemand I
Development; 2004 Jan; 131(2):479-87. PubMed ID: 14681185
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
