These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 16011254)

  • 1. [Advances in studies on selective RXR ligands].
    Mei JH; Wang MW
    Yao Xue Xue Bao; 2005 Apr; 40(4):294-8. PubMed ID: 16011254
    [No Abstract]   [Full Text] [Related]  

  • 2. Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN.
    Wagner CE; Jurutka PW
    Methods Mol Biol; 2019; 2019():109-121. PubMed ID: 31359392
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Studies on the structure-activity relationship of retinoids--Hansch analysis and 3D-OSAR studies on specific ligands of retinoid x receptor].
    Huang N; Chu F; Guo Z
    Yao Xue Xue Bao; 1998 Jun; 33(6):442-8. PubMed ID: 12016914
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
    Fitzgerald P; Teng M; Chandraratna RA; Heyman RA; Allegretto EA
    Cancer Res; 1997 Jul; 57(13):2642-50. PubMed ID: 9205071
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
    Boehm MF; Zhang L; Zhi L; McClurg MR; Berger E; Wagoner M; Mais DE; Suto CM; Davies JA; Heyman RA
    J Med Chem; 1995 Aug; 38(16):3146-55. PubMed ID: 7636877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes.
    Howell SR; Shirley MA; Ulm EH
    Drug Metab Dispos; 1998 Mar; 26(3):234-9. PubMed ID: 9492386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 9-cis-retinoic acid analogues with bulky hydrophobic rings: new RXR-selective agonists.
    Alvarez R; Vega MJ; Kammerer S; Rossin A; Germain P; Gronemeyer H; de Lera AR
    Bioorg Med Chem Lett; 2004 Dec; 14(24):6117-22. PubMed ID: 15546741
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modeling, synthesis and biological evaluation of potential retinoid X receptor-selective agonists: novel halogenated analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    Furmick JK; Kaneko I; Walsh AN; Yang J; Bhogal JS; Gray GM; Baso JC; Browder DO; Prentice JL; Montano LA; Huynh CC; Marcus LM; Tsosie DG; Kwon JS; Quezada A; Reyes NM; Lemming B; Saini P; van der Vaart A; Groy TL; Marshall PA; Jurutka PW; Wagner CE
    ChemMedChem; 2012 Sep; 7(9):1551-66. PubMed ID: 22927238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Immunomodulatory effects of RXR rexinoids: modulation of high-affinity IL-2R expression enhances susceptibility to denileukin diftitox.
    Gorgun G; Foss F
    Blood; 2002 Aug; 100(4):1399-403. PubMed ID: 12149223
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells.
    Simoni D; Roberti M; Invidiata FP; Rondanin R; Baruchello R; Malagutti C; Mazzali A; Rossi M; Grimaudo S; Capone F; Dusonchet L; Meli M; Raimondi MV; Landino M; D'Alessandro N; Tolomeo M; Arindam D; Lu S; Benbrook DM
    J Med Chem; 2001 Jul; 44(14):2308-18. PubMed ID: 11428925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).
    Heck MC; Wagner CE; Shahani PH; MacNeill M; Grozic A; Darwaiz T; Shimabuku M; Deans DG; Robinson NM; Salama SH; Ziller JW; Ma N; van der Vaart A; Marshall PA; Jurutka PW
    J Med Chem; 2016 Oct; 59(19):8924-8940. PubMed ID: 27592633
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design of selective nuclear receptor modulators: RAR and RXR as a case study.
    de Lera AR; Bourguet W; Altucci L; Gronemeyer H
    Nat Rev Drug Discov; 2007 Oct; 6(10):811-20. PubMed ID: 17906643
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The synthesis of tethered ligand dimers for PPARgamma-RXR protein heterodimers.
    Mohler DL; Shen G
    Org Biomol Chem; 2006 Jun; 4(11):2082-7. PubMed ID: 16729120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    Wagner CE; Jurutka PW; Marshall PA; Groy TL; van der Vaart A; Ziller JW; Furmick JK; Graeber ME; Matro E; Miguel BV; Tran IT; Kwon J; Tedeschi JN; Moosavi S; Danishyar A; Philp JS; Khamees RO; Jackson JN; Grupe DK; Badshah SL; Hart JW
    J Med Chem; 2009 Oct; 52(19):5950-66. PubMed ID: 19791803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254).
    Jurutka PW; Kaneko I; Yang J; Bhogal JS; Swierski JC; Tabacaru CR; Montano LA; Huynh CC; Jama RA; Mahelona RD; Sarnowski JT; Marcus LM; Quezada A; Lemming B; Tedesco MA; Fischer AJ; Mohamed SA; Ziller JW; Ma N; Gray GM; van der Vaart A; Marshall PA; Wagner CE
    J Med Chem; 2013 Nov; 56(21):8432-54. PubMed ID: 24180745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The influence of bexarotene, a selective agonist of the retinoid receptor X (RXR), and tazarotene, a selective agonist of the retinoid acid receptor (RAR), on bone metabolism in rats.
    Nowak B; Matuszewska A; Filipiak J; Nikodem A; Merwid-Ląd A; Pieśniewska M; Fereniec-Gołębiewska L; Kwiatkowska J; Szeląg A
    Adv Med Sci; 2016 Mar; 61(1):85-9. PubMed ID: 26569440
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of 9Z-retinoic acid analogs having 2-substituted benzo[b]furan.
    Okitsu T; Nakazawa D; Nakagawa K; Okano T; Wada A
    Chem Pharm Bull (Tokyo); 2010 Mar; 58(3):418-22. PubMed ID: 20190455
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patents.
    Schierle S; Merk D
    Expert Opin Ther Pat; 2019 Aug; 29(8):605-621. PubMed ID: 31298602
    [No Abstract]   [Full Text] [Related]  

  • 19. A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands.
    Crowe DL; Chandraratna RA
    Breast Cancer Res; 2004; 6(5):R546-55. PubMed ID: 15318936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The expression and activity of D-type cyclins in F9 embryonal carcinoma cells: modulation of growth by RXR-selective retinoids.
    Li Y; Glozak MA; Smith SM; Rogers MB
    Exp Cell Res; 1999 Dec; 253(2):372-84. PubMed ID: 10585260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.