BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 16011798)

  • 21. The herpesvirus alkaline exonuclease belongs to the restriction endonuclease PD-(D/E)XK superfamily: insight from molecular modeling and phylogenetic analysis.
    Bujnicki JM; Rychlewski L
    Virus Genes; 2001 Mar; 22(2):219-30. PubMed ID: 11324759
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.
    Nakonieczna J; Kaczorowski T; Obarska-Kosinska A; Bujnicki JM
    Appl Environ Microbiol; 2009 Jan; 75(1):212-23. PubMed ID: 18997032
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy.
    Chmiel AA; Radlinska M; Pawlak SD; Krowarsch D; Bujnicki JM; Skowronek KJ
    Protein Eng Des Sel; 2005 Apr; 18(4):181-9. PubMed ID: 15849215
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs.
    Bujnicki JM; Rychlewski L
    Gene; 2001 Apr; 267(2):183-91. PubMed ID: 11313145
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family.
    Gasiunas G; Sasnauskas G; Tamulaitis G; Urbanke C; Razaniene D; Siksnys V
    Nucleic Acids Res; 2008 Feb; 36(3):938-49. PubMed ID: 18086711
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inference of relationships in the 'twilight zone' of homology using a combination of bioinformatics and site-directed mutagenesis: a case study of restriction endonucleases Bsp6I and PvuII.
    Pawlak SD; Radlinska M; Chmiel AA; Bujnicki JM; Skowronek KJ
    Nucleic Acids Res; 2005; 33(2):661-71. PubMed ID: 15684412
    [TBL] [Abstract][Full Text] [Related]  

  • 27. An inactivated nuclease-like domain in RecC with novel function: implications for evolution.
    Rigden DJ
    BMC Struct Biol; 2005 Jun; 5():9. PubMed ID: 15985153
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.
    Saravanan M; Bujnicki JM; Cymerman IA; Rao DN; Nagaraja V
    Nucleic Acids Res; 2004; 32(20):6129-35. PubMed ID: 15562004
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Comparative genomics of the FtsK-HerA superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging.
    Iyer LM; Makarova KS; Koonin EV; Aravind L
    Nucleic Acids Res; 2004; 32(17):5260-79. PubMed ID: 15466593
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Type II restriction endonucleases: structure and mechanism.
    Pingoud A; Fuxreiter M; Pingoud V; Wende W
    Cell Mol Life Sci; 2005 Mar; 62(6):685-707. PubMed ID: 15770420
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mutability of an HNH nuclease imidazole general base and exchange of a deprotonation mechanism.
    Eastberg JH; Eklund J; Monnat R; Stoddard BL
    Biochemistry; 2007 Jun; 46(24):7215-25. PubMed ID: 17516660
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Polyphyletic evolution of type II restriction enzymes revisited: two independent sources of second-hand folds revealed.
    Bujnicki JM; Radlinska M; Rychlewski L
    Trends Biochem Sci; 2001 Jan; 26(1):9-11. PubMed ID: 11165501
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Evolutionary relationship of Alw26I, Eco31I and Esp3I, restriction endonucleases that recognise overlapping sequences.
    Bitinaite J; Mitkaite G; Dauksaite V; Jakubauskas A; Timinskas A; Vaisvila R; Lubys A; Janulaitis A
    Mol Genet Genomics; 2002 Jul; 267(5):664-72. PubMed ID: 12172806
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit.
    Kachalova GS; Rogulin EA; Yunusova AK; Artyukh RI; Perevyazova TA; Matvienko NI; Zheleznaya LA; Bartunik HD
    J Mol Biol; 2008 Dec; 384(2):489-502. PubMed ID: 18835275
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structure-based redesign of the catalytic/metal binding site of Cfr10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues.
    Skirgaila R; Grazulis S; Bozic D; Huber R; Siksnys V
    J Mol Biol; 1998 Jun; 279(2):473-81. PubMed ID: 9642051
    [TBL] [Abstract][Full Text] [Related]  

  • 36. SUPFAM--a database of potential protein superfamily relationships derived by comparing sequence-based and structure-based families: implications for structural genomics and function annotation in genomes.
    Pandit SB; Gosar D; Abhiman S; Sujatha S; Dixit SS; Mhatre NS; Sowdhamini R; Srinivasan N
    Nucleic Acids Res; 2002 Jan; 30(1):289-93. PubMed ID: 11752317
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements.
    Makarova KS; Wolf YI; van der Oost J; Koonin EV
    Biol Direct; 2009 Aug; 4():29. PubMed ID: 19706170
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Restriction endonucleases: natural and directed evolution.
    Gupta R; Capalash N; Sharma P
    Appl Microbiol Biotechnol; 2012 May; 94(3):583-99. PubMed ID: 22398859
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The crystal structure of D212 from sulfolobus spindle-shaped virus ragged hills reveals a new member of the PD-(D/E)XK nuclease superfamily.
    Menon SK; Eilers BJ; Young MJ; Lawrence CM
    J Virol; 2010 Jun; 84(12):5890-7. PubMed ID: 20375162
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the "midnight zone" of homology.
    Bujnicki JM
    Curr Protein Pept Sci; 2003 Oct; 4(5):327-37. PubMed ID: 14529527
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.