110 related articles for article (PubMed ID: 16019957)
1. Identification of metabolites of [14C]zonampanel, an a-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, following intravenous infusion in healthy volunteers.
Minematsu T; Sohda KY; Hashimoto T; Imai H; Usui T; Kamimura H
Xenobiotica; 2005 Apr; 35(4):359-71. PubMed ID: 16019957
[TBL] [Abstract][Full Text] [Related]
2. Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats.
Minematsu T; Hashimoto T; Aoki T; Usui T; Kamimura H
Drug Metab Dispos; 2008 Aug; 36(8):1496-504. PubMed ID: 18443035
[TBL] [Abstract][Full Text] [Related]
3. Application of LC-NMR for characterization of rat urinary metabolites of zonampanel monohydrate (YM872).
Sohda KY; Minematsu T; Hashimoto T; Suzumura K; Funatsu M; Suzuki K; Imai H; Usui T; Kamimura H
Chem Pharm Bull (Tokyo); 2004 Nov; 52(11):1322-5. PubMed ID: 15516754
[TBL] [Abstract][Full Text] [Related]
4. Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters.
Hashimoto T; Narikawa S; Huang XL; Minematsu T; Usui T; Kamimura H; Endou H
Drug Metab Dispos; 2004 Oct; 32(10):1096-102. PubMed ID: 15377641
[TBL] [Abstract][Full Text] [Related]
5. A novel AMPA receptor antagonist, YM872, reduces infarct size after middle cerebral artery occlusion in rats.
Kawasaki-Yatsugi S; Yatsugi S; Takahashi M; Toya T; Ichiki C; Shimizu-Sasamata M; Yamaguchi T; Minematsu K
Brain Res; 1998 May; 793(1-2):39-46. PubMed ID: 9630503
[TBL] [Abstract][Full Text] [Related]
6. In-vitro characterization of YM872, a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist.
Kohara A; Okada M; Tsutsumi R; Ohno K; Takahashi M; Shimizu-Sasamata M; Shishikura J; Inami H; Sakamoto S; Yamaguchi T
J Pharm Pharmacol; 1998 Jul; 50(7):795-801. PubMed ID: 9720630
[TBL] [Abstract][Full Text] [Related]
7. Characterization of renal tubular apical efflux of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in humans.
Minematsu T; Hashimoto T; Usui T; Kamimura H
Xenobiotica; 2008 Sep; 38(9):1191-202. PubMed ID: 18609448
[TBL] [Abstract][Full Text] [Related]
8. YM872: a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.
Takahashi M; Kohara A; Shishikura J; Kawasaki-Yatsugi S; Ni JW; Yatsugi S; Sakamoto S; Okada M; Shimizu-Sasamata M; Yamaguchi T
CNS Drug Rev; 2002; 8(4):337-52. PubMed ID: 12481190
[TBL] [Abstract][Full Text] [Related]
9. Pharmacokinetics and safety of the novel amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist YM90K in healthy men.
Umemura K; Kondo K; Ikeda Y; Teraya Y; Yoshida H; Homma M; Uematsu T; Nakashima M
J Clin Pharmacol; 1997 Aug; 37(8):719-27. PubMed ID: 9378844
[TBL] [Abstract][Full Text] [Related]
10. Neuroprotective effects of an AMPA receptor antagonist YM872 in a rat transient middle cerebral artery occlusion model.
Kawasaki-Yatsugi S; Ichiki C; Yatsugi S; Takahashi M; Shimizu-Sasamata M; Yamaguchi T; Minematsu K
Neuropharmacology; 2000 Jan; 39(2):211-7. PubMed ID: 10670416
[TBL] [Abstract][Full Text] [Related]
11. YM872, a novel selective alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, reduces brain damage after permanent focal cerebral ischemia in cats.
Takahashi M; Ni JW; Kawasaki-Yatsugi S; Toya T; Yatsugi SI; Shimizu-Sasamata M; Koshiya K; Shishikura JI; Sakamoto S; Yamaguchi T
J Pharmacol Exp Ther; 1998 Feb; 284(2):467-73. PubMed ID: 9454786
[TBL] [Abstract][Full Text] [Related]
12. The systemically administered competitive AMPA receptor antagonist, YM872, has analgesic effects on thermal or formalin-induced pain in rats.
Nishiyama T; Gyermek L; Lee C; Kawasaki-Yatsugi S; Yamaguchi T
Anesth Analg; 1999 Dec; 89(6):1534-7. PubMed ID: 10589643
[TBL] [Abstract][Full Text] [Related]
13. Effect of AMPA receptor antagonist YM872 on cerebral hematoma size and neurological recovery in the intracerebral hemorrhage rat model.
Terai K; Suzuki M; Sasamata M; Yatsugi Si; Yamaguchi T; Miyata K
Eur J Pharmacol; 2003 Apr; 467(1-3):95-101. PubMed ID: 12706461
[TBL] [Abstract][Full Text] [Related]
14. Neuroprotective efficacy of YM872, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, after permanent middle cerebral artery occlusion in rats.
Takahashi M; Ni JW; Kawasaki-Yatsugi S; Toya T; Ichiki C; Yatsugi SI; Koshiya K; Shimizu-Sasamata M; Yamaguchi T
J Pharmacol Exp Ther; 1998 Nov; 287(2):559-66. PubMed ID: 9808681
[TBL] [Abstract][Full Text] [Related]
15. The spinal antinociceptive effects of a novel competitive AMPA receptor antagonist, YM872, on thermal or formalin-induced pain in rats.
Nishiyama T; Gyermek L; Lee C; Kawasaki-Yatsugi S; Yamaguchi T
Anesth Analg; 1999 Jul; 89(1):143-7. PubMed ID: 10389792
[TBL] [Abstract][Full Text] [Related]
16. Neuroprotective effect of the novel glutamate AMPA receptor antagonist YM872 assessed with in vivo MR imaging of rat MCA occlusion.
Håberg A; Takahashi M; Yamaguchi T; Hjelstuen M; Haraldseth O
Brain Res; 1998 Nov; 811(1-2):63-70. PubMed ID: 9804894
[TBL] [Abstract][Full Text] [Related]
17. Effect of YM872, a selective and highly water-soluble AMPA receptor antagonist, in the rat kindling and rekindling model of epilepsy.
Hara H; Yamada N; Kodama M; Matsumoto Y; Wake Y; Kuroda S
Eur J Pharmacol; 2006 Feb; 531(1-3):59-65. PubMed ID: 16403498
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetics of the anticoagulant 14C-DX-9065a in the healthy male volunteer after a single intravenous dose.
Murayama N; McMahon H; Young CG; McCracken NW; Okamura Y; Hakusui H; Tanaka M
Xenobiotica; 2000 May; 30(5):515-21. PubMed ID: 10875684
[TBL] [Abstract][Full Text] [Related]
19. Pharmacokinetics of ethylene glycol. III. Plasma disposition and metabolic fate after single increasing intravenous, peroral, or percutaneous doses in the male Sprague-Dawley rat.
Frantz SW; Beskitt JL; Tallant MJ; Zourelias LA; Ballantyne B
Xenobiotica; 1996 May; 26(5):515-39. PubMed ID: 8736063
[TBL] [Abstract][Full Text] [Related]
20. The effects of an AMPA receptor antagonist on the neurotoxicity of tetracaine intrathecally administered in rabbits.
Koizumi Y; Matsumoto M; Yamashita A; Tsuruta S; Ohtake T; Sakabe T
Anesth Analg; 2006 Mar; 102(3):930-6. PubMed ID: 16492854
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
