221 related articles for article (PubMed ID: 16021692)
1. Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.
Choudhary MI; Nawaz SA; Zaheer-ul-Haq ; Azim MK; Ghayur MN; Lodhi MA; Jalil S; Khalid A; Ahmed A; Rode BM; Atta-ur-Rahman ; Gilani AU; Ahmad VU
Biochem Biophys Res Commun; 2005 Jul; 332(4):1171-7. PubMed ID: 16021692
[TBL] [Abstract][Full Text] [Related]
2. Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties.
Choudhary MI; Nawaz SA; ul-Haq Z; Lodhi MA; Ghayur MN; Jalil S; Riaz N; Yousuf S; Malik A; Gilani AH; ur-Rahman A
Biochem Biophys Res Commun; 2005 Aug; 334(1):276-87. PubMed ID: 16108094
[TBL] [Abstract][Full Text] [Related]
3. Kinetics and structure-activity relationship studies on pregnane-type steroidal alkaloids that inhibit cholinesterases.
Khalid A; Zaheer-ul-Haq ; Anjum S; Khan MR; Atta-ur-Rahman ; Choudhary MI
Bioorg Med Chem; 2004 May; 12(9):1995-2003. PubMed ID: 15080903
[TBL] [Abstract][Full Text] [Related]
4. Structural insight into the inhibition of acetylcholinesterase by 2,3,4, 5-tetrahydro-1, 5-benzothiazepines.
Nawaz SA; Umbreen S; Kahlid A; Ansari FL; Choudhary MI
J Enzyme Inhib Med Chem; 2008 Apr; 23(2):206-12. PubMed ID: 18343905
[TBL] [Abstract][Full Text] [Related]
5. Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
Saxena A; Fedorko JM; Vinayaka CR; Medhekar R; Radić Z; Taylor P; Lockridge O; Doctor BP
Eur J Biochem; 2003 Nov; 270(22):4447-58. PubMed ID: 14622273
[TBL] [Abstract][Full Text] [Related]
6. Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.
Kryger G; Silman I; Sussman JL
Structure; 1999 Mar; 7(3):297-307. PubMed ID: 10368299
[TBL] [Abstract][Full Text] [Related]
7. Cholinesterase inhibitory and spasmolytic potential of steroidal alkaloids.
Khalid A; Zaheer-ul-Haq ; Ghayur MN; Feroz F; Atta-ur-Rahman ; Gilani AH; Choudhary MI
J Steroid Biochem Mol Biol; 2004 Dec; 92(5):477-84. PubMed ID: 15795993
[TBL] [Abstract][Full Text] [Related]
8. Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae).
Wan Othman WNN; Liew SY; Khaw KY; Murugaiyah V; Litaudon M; Awang K
Bioorg Med Chem; 2016 Sep; 24(18):4464-4469. PubMed ID: 27492195
[TBL] [Abstract][Full Text] [Related]
9. Docking of the alkaloid geissospermine into acetylcholinesterase: a natural scaffold targeting the treatment of Alzheimer's disease.
Araújo JQ; Lima JA; Pinto Ada C; de Alencastro RB; Albuquerque MG
J Mol Model; 2011 Jun; 17(6):1401-12. PubMed ID: 20844909
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors.
Nuthakki VK; Mudududdla R; Sharma A; Kumar A; Bharate SB
Bioorg Chem; 2019 Sep; 90():103062. PubMed ID: 31220673
[TBL] [Abstract][Full Text] [Related]
11. New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots.
Salehi A; Zolfaghari B; Aghaei M; Sirous H; Sadeghi M; Gholami MR; Reisi P; Ghanadian M
Daru; 2024 Jun; 32(1):237-251. PubMed ID: 38498253
[TBL] [Abstract][Full Text] [Related]
12. Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity.
Wong DM; Greenblatt HM; Dvir H; Carlier PR; Han YF; Pang YP; Silman I; Sussman JL
J Am Chem Soc; 2003 Jan; 125(2):363-73. PubMed ID: 12517147
[TBL] [Abstract][Full Text] [Related]
13. Geissoschizoline, a promising alkaloid for Alzheimer's disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking.
Lima JA; R Costa TW; da Fonseca ACC; do Amaral RF; Nascimento MDDSB; Santos-Filho OA; de Miranda ALP; Ferreira Neto DC; Lima FRS; Hamerski L; Tinoco LW
Bioorg Chem; 2020 Nov; 104():104215. PubMed ID: 32920358
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer's Disease Agents Using Pharmacophore, 3D-QSAR, and Molecular Docking Approaches.
Pang X; Fu H; Yang S; Wang L; Liu AL; Wu S; Du GH
Molecules; 2017 Jul; 22(8):. PubMed ID: 28933746
[TBL] [Abstract][Full Text] [Related]
16. Amino acid residues involved in the interaction of acetylcholinesterase and butyrylcholinesterase with the carbamates Ro 02-0683 and bambuterol, and with terbutaline.
Kovarik Z; Radić Z; Grgas B; Skrinjarić-Spoljar M; Reiner E; Simeon-Rudolf V
Biochim Biophys Acta; 1999 Aug; 1433(1-2):261-71. PubMed ID: 10446376
[TBL] [Abstract][Full Text] [Related]
17. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design.
Greenblatt HM; Guillou C; Guénard D; Argaman A; Botti S; Badet B; Thal C; Silman I; Sussman JL
J Am Chem Soc; 2004 Dec; 126(47):15405-11. PubMed ID: 15563167
[TBL] [Abstract][Full Text] [Related]
18. Molecular interactions of 4-acetoxy-plakinamine B with peripheral anionic and other catalytic subsites of the aromatic gorge of acetylcholinesterase: computational and structural insights.
Khan I; Samad A; Khan AZ; Habtemariam S; Badshah A; Abdullah SM; Ullah N; Khan A; Zia-Ul-Haq M
Pharm Biol; 2013 Jun; 51(6):722-7. PubMed ID: 23570516
[TBL] [Abstract][Full Text] [Related]
19. Phthalimide-Derived N-Benzylpyridinium Halides Targeting Cholinesterases: Synthesis and Bioactivity of New Potential Anti-Alzheimer's Disease Agents.
Saeedi M; Golipoor M; Mahdavi M; Moradi A; Nadri H; Emami S; Foroumadi A; Shafiee A
Arch Pharm (Weinheim); 2016 Apr; 349(4):293-301. PubMed ID: 26898241
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target.
Harel M; Kleywegt GJ; Ravelli RB; Silman I; Sussman JL
Structure; 1995 Dec; 3(12):1355-66. PubMed ID: 8747462
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]