These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

567 related articles for article (PubMed ID: 16024780)

  • 1. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.
    Chan DA; Sutphin PD; Yen SE; Giaccia AJ
    Mol Cell Biol; 2005 Aug; 25(15):6415-26. PubMed ID: 16024780
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation.
    Percy MJ; Mooney SM; McMullin MF; Flores A; Lappin TR; Lee FS
    Mol Cancer; 2003 Sep; 2():31. PubMed ID: 14521712
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
    Kageyama Y; Koshiji M; To KK; Tian YM; Ratcliffe PJ; Huang LE
    FASEB J; 2004 Jun; 18(9):1028-30. PubMed ID: 15084514
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
    EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.
    Lando D; Peet DJ; Whelan DA; Gorman JJ; Whitelaw ML
    Science; 2002 Feb; 295(5556):858-61. PubMed ID: 11823643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.
    Huang J; Zhao Q; Mooney SM; Lee FS
    J Biol Chem; 2002 Oct; 277(42):39792-800. PubMed ID: 12181324
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation.
    Fu XS; Choi E; Bubley GJ; Balk SP
    Prostate; 2005 May; 63(3):215-21. PubMed ID: 15538748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.
    Chan DA; Sutphin PD; Denko NC; Giaccia AJ
    J Biol Chem; 2002 Oct; 277(42):40112-7. PubMed ID: 12186875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.
    Nikinmaa M; Pursiheimo S; Soitamo AJ
    J Cell Sci; 2004 Jul; 117(Pt 15):3201-6. PubMed ID: 15199099
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    Miller F; Kentsis A; Osman R; Pan ZQ
    J Biol Chem; 2005 Mar; 280(9):7985-96. PubMed ID: 15611064
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
    J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
    [TBL] [Abstract][Full Text] [Related]  

  • 13. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
    Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
    Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
    Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate.
    He W; Batty-Stuart S; Lee JE; Ohh M
    J Mol Biol; 2021 Nov; 433(22):167244. PubMed ID: 34537235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
    Masson N; Willam C; Maxwell PH; Pugh CW; Ratcliffe PJ
    EMBO J; 2001 Sep; 20(18):5197-206. PubMed ID: 11566883
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
    Pientka FK; Hu J; Schindler SG; Brix B; Thiel A; Jöhren O; Fandrey J; Berchner-Pfannschmidt U; Depping R
    J Cell Sci; 2012 Nov; 125(Pt 21):5168-76. PubMed ID: 22946054
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours.
    Snell CE; Turley H; McIntyre A; Li D; Masiero M; Schofield CJ; Gatter KC; Harris AL; Pezzella F
    PLoS One; 2014; 9(2):e88955. PubMed ID: 24563687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
    Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
    Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.