BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 16030016)

  • 1. Increased production of functional recombinant human clotting factor IX by baby hamster kidney cells engineered to overexpress VKORC1, the vitamin K 2,3-epoxide-reducing enzyme of the vitamin K cycle.
    Wajih N; Hutson SM; Owen J; Wallin R
    J Biol Chem; 2005 Sep; 280(36):31603-7. PubMed ID: 16030016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system.
    Wajih N; Sane DC; Hutson SM; Wallin R
    J Biol Chem; 2005 Mar; 280(11):10540-7. PubMed ID: 15640149
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced functional recombinant factor IX production by human embryonic kidney cells engineered to overexpress VKORC1.
    Pakdaman SF; Vatandoost J; Bos MHA
    Biotechnol Prog; 2020 Mar; 36(2):e2938. PubMed ID: 31677255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection.
    Wajih N; Owen J; Wallin R
    Thromb Res; 2008; 122(3):405-10. PubMed ID: 18177690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of biologically active human clotting factor IX in Drosophila S2 cells: γ-carboxylation of a human vitamin K-dependent protein by the insect enzyme.
    Vatandoost J; Zomorodipour A; Sadeghizadeh M; Aliyari R; Bos MH; Ataei F
    Biotechnol Prog; 2012; 28(1):45-51. PubMed ID: 22012919
    [TBL] [Abstract][Full Text] [Related]  

  • 6. siRNA silencing of calumenin enhances functional factor IX production.
    Wajih N; Hutson SM; Wallin R
    Blood; 2006 Dec; 108(12):3757-60. PubMed ID: 16902154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. VKORC1: a warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors.
    Wallin R; Wajih N; Hutson SM
    Vitam Horm; 2008; 78():227-46. PubMed ID: 18374197
    [TBL] [Abstract][Full Text] [Related]  

  • 8. r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.
    Hallgren KW; Qian W; Yakubenko AV; Runge KW; Berkner KL
    Biochemistry; 2006 May; 45(17):5587-98. PubMed ID: 16634640
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disulfide-dependent protein folding is linked to operation of the vitamin K cycle in the endoplasmic reticulum. A protein disulfide isomerase-VKORC1 redox enzyme complex appears to be responsible for vitamin K1 2,3-epoxide reduction.
    Wajih N; Hutson SM; Wallin R
    J Biol Chem; 2007 Jan; 282(4):2626-35. PubMed ID: 17124179
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carboxylase overexpression effects full carboxylation but poor release and secretion of factor IX: implications for the release of vitamin K-dependent proteins.
    Hallgren KW; Hommema EL; McNally BA; Berkner KL
    Biochemistry; 2002 Dec; 41(50):15045-55. PubMed ID: 12475254
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Vitamin K epoxide reductase: Fresh blood for oral anticoagulant therapies].
    Loriot MA; Beaune P
    Rev Med Interne; 2006 Dec; 27(12):979-82. PubMed ID: 17070618
    [TBL] [Abstract][Full Text] [Related]  

  • 12. VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.
    Spohn G; Kleinridders A; Wunderlich FT; Watzka M; Zaucke F; Blumbach K; Geisen C; Seifried E; Müller C; Paulsson M; Brüning JC; Oldenburg J
    Thromb Haemost; 2009 Jun; 101(6):1044-50. PubMed ID: 19492146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of propeptide amino acid substitution in γ-carboxylation, activity and expression of recombinant human coagulation factor IX.
    Vatandoost J; Zarei Sani O
    Biotechnol Prog; 2018 Mar; 34(2):515-520. PubMed ID: 29086495
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vitamin K epoxide reductase significantly improves carboxylation in a cell line overexpressing factor X.
    Sun YM; Jin DY; Camire RM; Stafford DW
    Blood; 2005 Dec; 106(12):3811-5. PubMed ID: 16081695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vitamin K 2,3-epoxide reductase and the vitamin K-dependent gamma-carboxylation system.
    Wallin R; Sane DC; Hutson SM
    Thromb Res; 2002 Nov; 108(4):221-6. PubMed ID: 12617985
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats.
    Wajih N; Sane DC; Hutson SM; Wallin R
    J Biol Chem; 2004 Jun; 279(24):25276-83. PubMed ID: 15075329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells.
    Kaufman RJ; Wasley LC; Furie BC; Furie B; Shoemaker CB
    J Biol Chem; 1986 Jul; 261(21):9622-8. PubMed ID: 3733688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human Cells as Platform to Produce Gamma-Carboxylated Proteins.
    de Sousa Bomfim A; de Freitas MCC; Covas DT; de Sousa Russo EM
    Methods Mol Biol; 2018; 1674():49-61. PubMed ID: 28921427
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The vitamin K cycle.
    Oldenburg J; Marinova M; Müller-Reible C; Watzka M
    Vitam Horm; 2008; 78():35-62. PubMed ID: 18374189
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Arg98Trp mutation in human VKORC1 causing VKCFD2 disrupts a di-arginine-based ER retention motif.
    Czogalla KJ; Biswas A; Rost S; Watzka M; Oldenburg J
    Blood; 2014 Aug; 124(8):1354-62. PubMed ID: 24963046
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.