These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 16030156)

  • 21. Point mutations in the melanocortin-4 receptor cause variable obesity in mice.
    Meehan TP; Tabeta K; Du X; Woodward LS; Firozi K; Beutler B; Justice MJ
    Mamm Genome; 2006 Dec; 17(12):1162-71. PubMed ID: 17143585
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
    Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C
    J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Gain-of-function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta-analysis.
    Qasim A; Mayhew AJ; Ehtesham S; Alyass A; Volckmar AL; Herpertz S; Hinney A; Hebebrand J; Meyre D
    Obes Rev; 2019 Jan; 20(1):13-21. PubMed ID: 30306707
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A novel melanocortin-4 receptor mutation MC4R-P272L associated with severe obesity has increased propensity to be ubiquitinated in the ER in the face of correct folding.
    Granell S; Serra-Juhé C; Martos-Moreno GÁ; Díaz F; Pérez-Jurado LA; Baldini G; Argente J
    PLoS One; 2012; 7(12):e50894. PubMed ID: 23251400
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Gene variants and binge eating as predictors of comorbidity and outcome of treatment in severe obesity.
    Potoczna N; Branson R; Kral JG; Piec G; Steffen R; Ricklin T; Hoehe MR; Lentes KU; Horber FF
    J Gastrointest Surg; 2004 Dec; 8(8):971-81; discussion 981-2. PubMed ID: 15585384
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity.
    Larsen LH; Echwald SM; Sørensen TI; Andersen T; Wulff BS; Pedersen O
    J Clin Endocrinol Metab; 2005 Jan; 90(1):219-24. PubMed ID: 15486053
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.
    René P; Le Gouill C; Pogozheva ID; Lee G; Mosberg HI; Farooqi IS; Valenzano KJ; Bouvier M
    J Pharmacol Exp Ther; 2010 Dec; 335(3):520-32. PubMed ID: 20826565
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The Melanocortin System behind the Dysfunctional Eating Behaviors.
    Micioni Di Bonaventura E; Botticelli L; Tomassoni D; Tayebati SK; Micioni Di Bonaventura MV; Cifani C
    Nutrients; 2020 Nov; 12(11):. PubMed ID: 33202557
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Functional studies on twenty novel naturally occurring melanocortin-4 receptor mutations.
    Wang ZQ; Tao YX
    Biochim Biophys Acta; 2011 Sep; 1812(9):1190-9. PubMed ID: 21729752
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Functional characterization of variants in MC4R gene promoter region found in obese children.
    Tan KM; Ooi SQ; Ong SG; Kwan CS; Chan RM; Seng Poh LK; Mendoza J; Heng CK; Loke KY; Lee YS
    J Clin Endocrinol Metab; 2014 May; 99(5):E931-5. PubMed ID: 24512492
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mutations in melanocortin-4 receptor and human obesity.
    Tao YX
    Prog Mol Biol Transl Sci; 2009; 88():173-204. PubMed ID: 20374728
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Differential Signaling Profiles of MC4R Mutations with Three Different Ligands.
    Paisdzior S; Dimitriou IM; Schöpe PC; Annibale P; Scheerer P; Krude H; Lohse MJ; Biebermann H; Kühnen P
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32059383
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Defect in MAPK signaling as a cause for monogenic obesity caused by inactivating mutations in the melanocortin-4 receptor gene.
    He S; Tao YX
    Int J Biol Sci; 2014; 10(10):1128-37. PubMed ID: 25332687
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants.
    Sharma S; Thibodeau S; Lytton J
    Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165835. PubMed ID: 32423884
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population.
    Rouskas K; Meyre D; Stutzmann F; Paletas K; Papazoglou D; Vatin V; Marchand M; Kouvatsi A; Froguel P
    Obesity (Silver Spring); 2012 Nov; 20(11):2278-82. PubMed ID: 22447289
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study.
    Bonnefond A; Keller R; Meyre D; Stutzmann F; Thuillier D; Stefanov DG; Froguel P; Horber FF; Kral JG
    Diabetes Care; 2016 Aug; 39(8):1384-92. PubMed ID: 27222505
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
    Collet TH; Dubern B; Mokrosinski J; Connors H; Keogh JM; Mendes de Oliveira E; Henning E; Poitou-Bernert C; Oppert JM; Tounian P; Marchelli F; Alili R; Le Beyec J; Pépin D; Lacorte JM; Gottesdiener A; Bounds R; Sharma S; Folster C; Henderson B; O'Rahilly S; Stoner E; Gottesdiener K; Panaro BL; Cone RD; Clément K; Farooqi IS; Van der Ploeg LHT
    Mol Metab; 2017 Oct; 6(10):1321-1329. PubMed ID: 29031731
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female.
    Donohoue PA; Tao YX; Collins M; Yeo GS; O'Rahilly S; Segaloff DL
    J Clin Endocrinol Metab; 2003 Dec; 88(12):5841-5. PubMed ID: 14671178
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
    Ayers KL; Glicksberg BS; Garfield AS; Longerich S; White JA; Yang P; Du L; Chittenden TW; Gulcher JR; Roy S; Fiedorek F; Gottesdiener K; Cohen S; North KE; Schadt EE; Li SD; Chen R; Van der Ploeg LHT
    J Clin Endocrinol Metab; 2018 Jul; 103(7):2601-2612. PubMed ID: 29726959
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Insights into the Allosteric Mechanism of Setmelanotide (RM-493) as a Potent and First-in-Class Melanocortin-4 Receptor (MC4R) Agonist To Treat Rare Genetic Disorders of Obesity through an in Silico Approach.
    Falls BA; Zhang Y
    ACS Chem Neurosci; 2019 Mar; 10(3):1055-1065. PubMed ID: 30048591
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.