BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 16033258)

  • 21. Thiouracil antithyroid drugs as a new class of neuronal nitric oxide synthase inhibitors.
    Palumbo A; d'Ischia M
    Biochem Biophys Res Commun; 2001 Apr; 282(3):793-7. PubMed ID: 11401533
    [TBL] [Abstract][Full Text] [Related]  

  • 22. L-arginine binding to human inducible nitric oxide synthase: an antisymmetric funnel route toward isoform-specific inhibitors?
    Floquet N; Hernandez JF; Boucher JL; Martinez J
    J Chem Inf Model; 2011 Jun; 51(6):1325-35. PubMed ID: 21574590
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Formation of nitric oxide synthase-iron(II) nitrosoalkane complexes: severe restriction of access to the iron(II) site in the presence of tetrahydrobiopterin.
    Renodon A; Boucher JL; Wu C; Gachhui R; Sari MA; Mansuy D; Stuehr D
    Biochemistry; 1998 May; 37(18):6367-74. PubMed ID: 9572852
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase.
    Martin NI; Woodward JJ; Winter MB; Beeson WT; Marletta MA
    J Am Chem Soc; 2007 Oct; 129(41):12563-70. PubMed ID: 17892291
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Low-temperature optical absorption spectra suggest a redox role for tetrahydrobiopterin in both steps of nitric oxide synthase catalysis.
    Gorren AC; Bec N; Schrammel A; Werner ER; Lange R; Mayer B
    Biochemistry; 2000 Sep; 39(38):11763-70. PubMed ID: 10995244
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.
    Grädler U; Fuchss T; Ulrich WR; Boer R; Strub A; Hesslinger C; Anézo C; Diederichs K; Zaliani A
    Bioorg Med Chem Lett; 2011 Jul; 21(14):4228-32. PubMed ID: 21684157
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Alterations in the modulation of cerebrovascular tone and blood flow by nitric oxide synthases in SHRsp with stroke.
    Daneshtalab N; Smeda JS
    Cardiovasc Res; 2010 Apr; 86(1):160-8. PubMed ID: 20008826
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Active-site structure analysis of recombinant human inducible nitric oxide synthase using imidazole.
    Chabin RM; McCauley E; Calaycay JR; Kelly TM; MacNaul KL; Wolfe GC; Hutchinson NI; Madhusudanaraju S; Schmidt JA; Kozarich JW; Wong KK
    Biochemistry; 1996 Jul; 35(29):9567-75. PubMed ID: 8755738
    [TBL] [Abstract][Full Text] [Related]  

  • 29. 4,4-Difluorinated analogues of l-arginine and N(G)-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase.
    Martin NI; Woodward JJ; Winter MB; Marletta MA
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1758-62. PubMed ID: 19230661
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Insights into ligand selectivity in nitric oxide synthase isoforms: a molecular dynamics study.
    Aparna V; Desiraju GR; Gopalakrishnan B
    J Mol Graph Model; 2007 Sep; 26(2):457-70. PubMed ID: 17350298
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxide synthase inhibitors.
    Prins LH; Petzer JP; Malan SF
    Bioorg Med Chem; 2009 Nov; 17(21):7523-30. PubMed ID: 19804982
    [TBL] [Abstract][Full Text] [Related]  

  • 32. CO exchange of the oxyferrous complexes of endothelial nitric-oxide synthase oxygenase domain in the presence of 4-amino-tetrahydrobiopterin.
    Marchal S; Lange R; Sørlie M; Andersson KK; Gorren AC; Mayer B
    J Inorg Biochem; 2004 Jul; 98(7):1217-22. PubMed ID: 15219988
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-function aspects in the nitric oxide synthases.
    Stuehr DJ
    Annu Rev Pharmacol Toxicol; 1997; 37():339-59. PubMed ID: 9131257
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Chiral recognition at the heme active site of nitric oxide synthase is markedly enhanced by L-arginine and 5,6,7,8-tetrahydrobiopterin.
    Nakano K; Sagami I; Daff S; Shimizu T
    Biochem Biophys Res Commun; 1998 Jul; 248(3):767-72. PubMed ID: 9704002
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 2-Iminopyrrolidines as potent and selective inhibitors of human inducible nitric oxide synthase.
    Hagen TJ; Bergmanis AA; Kramer SW; Fok KF; Schmelzer AE; Pitzele BS; Swenton L; Jerome GM; Kornmeier CM; Moore WM; Branson LF; Connor JR; Manning PT; Currie MG; Hallinan EA
    J Med Chem; 1998 Sep; 41(19):3675-83. PubMed ID: 9733492
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Tetrahydrobiopterin inhibits monomerization and is consumed during catalysis in neuronal NO synthase.
    Reif A; Fröhlich LG; Kotsonis P; Frey A; Bömmel HM; Wink DA; Pfleiderer W; Schmidt HH
    J Biol Chem; 1999 Aug; 274(35):24921-9. PubMed ID: 10455167
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.
    Aoyagi M; Arvai AS; Ghosh S; Stuehr DJ; Tainer JA; Getzoff ED
    Biochemistry; 2001 Oct; 40(43):12826-32. PubMed ID: 11669619
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.
    Alderton WK; Boyhan A; Lowe PN
    Biochem J; 1998 May; 332 ( Pt 1)(Pt 1):195-201. PubMed ID: 9576868
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Titration of low K(d) binding sites: binding of arginine analogs to nitric oxide synthases.
    Smith SM; Sham C; Roman L; Martasek P; Salerno JC
    Nitric Oxide; 2001; 5(5):442-52. PubMed ID: 11587559
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines.
    Bretscher LE; Li H; Poulos TL; Griffith OW
    J Biol Chem; 2003 Nov; 278(47):46789-97. PubMed ID: 12960153
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.