BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 16033949)

  • 21. Clinical implications of CES2 RNA expression in neuroblastoma.
    Uchida K; Otake K; Tanaka K; Hashimoto K; Saigusa S; Matsushita K; Koike Y; Inoue M; Ueeda M; Okugawa Y; Inoue Y; Mohri Y; Kusunoki M
    J Pediatr Surg; 2013 Mar; 48(3):502-9. PubMed ID: 23480903
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Relationship between
    Ishimine M; Lee HC; Nakaoka H; Orita H; Kobayashi T; Mizuguchi K; Endo M; Inoue I; Sato K; Yokomizo T
    Dis Markers; 2018; 2018():5280736. PubMed ID: 29651325
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pharmacogenomic assessment of carboxylesterases 1 and 2.
    Marsh S; Xiao M; Yu J; Ahluwalia R; Minton M; Freimuth RR; Kwok PY; McLeod HL
    Genomics; 2004 Oct; 84(4):661-8. PubMed ID: 15475243
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity.
    Takumi S; Shimono T; Ikema S; Hotta Y; Chigwechokha PK; Shiozaki K; Sugiyama Y; Hashimoto M; Furukawa T; Komatsu M
    Comp Biochem Physiol C Toxicol Pharmacol; 2017 Apr; 194():22-27. PubMed ID: 28163251
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Difference in substrate specificity of carboxylesterase and arylacetamide deacetylase between dogs and humans.
    Yoshida T; Fukami T; Kurokawa T; Gotoh S; Oda A; Nakajima M
    Eur J Pharm Sci; 2018 Jan; 111():167-176. PubMed ID: 28966098
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11).
    Potter PM; Pawlik CA; Morton CL; Naeve CW; Danks MK
    Cancer Res; 1998 Jun; 58(12):2646-51. PubMed ID: 9635592
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes.
    Cho E; Islam SMBU; Jiang F; Park JE; Lee B; Kim ND; Hwang TH
    Cancer Res Treat; 2020 Jan; 52(1):309-319. PubMed ID: 31401821
    [TBL] [Abstract][Full Text] [Related]  

  • 28. CES2, ABCG2, TS and Topo-I primary and synchronous metastasis expression and clinical outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI regimen.
    Silvestris N; Simone G; Partipilo G; Scarpi E; Lorusso V; Brunetti AE; Maiello E; Paradiso A; Mangia A
    Int J Mol Sci; 2014 Sep; 15(9):15767-77. PubMed ID: 25198900
    [TBL] [Abstract][Full Text] [Related]  

  • 29. An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.
    Wierdl M; Tsurkan L; Hyatt JL; Edwards CC; Hatfield MJ; Morton CL; Houghton PJ; Danks MK; Redinbo MR; Potter PM
    Cancer Gene Ther; 2008 Mar; 15(3):183-92. PubMed ID: 18188187
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mouse liver and kidney carboxylesterase (M-LK) rapidly hydrolyzes antitumor prodrug irinotecan and the N-terminal three quarter sequence determines substrate selectivity.
    Xie M; Yang D; Wu M; Xue B; Yan B
    Drug Metab Dispos; 2003 Jan; 31(1):21-7. PubMed ID: 12485949
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.
    Hatfield MJ; Tsurkan L; Hyatt JL; Yu X; Edwards CC; Hicks LD; Wadkins RM; Potter PM
    Br J Pharmacol; 2010 Aug; 160(8):1916-28. PubMed ID: 20649590
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population.
    Matsumoto J; Ariyoshi N; Ishii I; Kitada M
    J Hum Genet; 2013 May; 58(5):267-72. PubMed ID: 23466819
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Clinical implications of genetic variation in carboxylesterase drug metabolism.
    Chen F; Zhang B; Parker RB; Laizure SC
    Expert Opin Drug Metab Toxicol; 2018 Feb; 14(2):131-142. PubMed ID: 29264996
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.
    Xiao D; Shi D; Yang D; Barthel B; Koch TH; Yan B
    Biochem Pharmacol; 2013 Feb; 85(3):439-47. PubMed ID: 23228697
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Effect of Genetic Variation of
    Dompreh A; Tang X; Zhou J; Yang H; Topletz A; Adu Ahwireng E; Antwi S; Enimil A; Langaee T; Peloquin CA; Court MH; Kwara A
    Antimicrob Agents Chemother; 2018 Mar; 62(3):. PubMed ID: 29263072
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Secreted and tumour targeted human carboxylesterase for activation of irinotecan.
    Oosterhoff D; Pinedo HM; van der Meulen IH; de Graaf M; Sone T; Kruyt FA; van Beusechem VW; Haisma HJ; Gerritsen WR
    Br J Cancer; 2002 Sep; 87(6):659-64. PubMed ID: 12237777
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Near-infrared emission tracks inter-individual variability of carboxylesterase-2 via a novel molecular substrate.
    Liu X; Li X; Dong P; Wu Z; Gao J; Wang Q
    Mikrochim Acta; 2020 May; 187(6):313. PubMed ID: 32377952
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Intracellular conversion of irinotecan to its active form, SN-38, by native carboxylesterase in human non-small cell lung cancer.
    Ohtsuka K; Inoue S; Kameyama M; Kanetoshi A; Fujimoto T; Takaoka K; Araya Y; Shida A
    Lung Cancer; 2003 Aug; 41(2):187-98. PubMed ID: 12871782
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation and expression of aberrant methylation on irinotecan metabolic genes CES2, UGT1A1 and GUSB in the in-vitro cultured colorectal cancer cells.
    Xie FW; Peng YH; Chen X; Chen X; Li J; Yu ZY; Wang WW; Ouyang XN
    Biomed Pharmacother; 2014 Feb; 68(1):31-7. PubMed ID: 24439671
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Overexpressed CES2 has prognostic value in CRC and knockdown CES2 reverses L-OHP-resistance in CRC cells by inhibition of the PI3K signaling pathway.
    Zhang Y; Sun L; Sun Y; Chen Y; Wang X; Xu M; Chi P; Xu Z; Lu X
    Exp Cell Res; 2020 Apr; 389(1):111856. PubMed ID: 31981591
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.