BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 16039853)

  • 1. Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
    Mincione F; Starnotti M; Masini E; Bacciottini L; Scrivanti C; Casini A; Vullo D; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 Sep; 15(17):3821-7. PubMed ID: 16039853
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.
    de Leval X; Ilies M; Casini A; Dogné JM; Scozzafava A; Masini E; Mincione F; Starnotti M; Supuran CT
    J Med Chem; 2004 May; 47(11):2796-804. PubMed ID: 15139757
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?
    Vullo D; Innocenti A; Nishimori I; Pastorek J; Scozzafava A; Pastoreková S; Supuran CT
    Bioorg Med Chem Lett; 2005 Feb; 15(4):963-9. PubMed ID: 15686894
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?
    Scozzafava A; Menabuoni L; Mincione F; Briganti F; Mincione G; Supuran CT
    J Med Chem; 1999 Jul; 42(14):2641-50. PubMed ID: 10411484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides.
    Ozensoy O; Nishimori I; Vullo D; Puccetti L; Scozzafava A; Supuran CT
    Bioorg Med Chem; 2005 Nov; 13(22):6089-93. PubMed ID: 16006130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
    Cecchi A; Winum JY; Innocenti A; Vullo D; Montero JL; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2004 Dec; 14(23):5775-80. PubMed ID: 15501039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.
    Vullo D; Voipio J; Innocenti A; Rivera C; Ranki H; Scozzafava A; Kaila K; Supuran CT
    Bioorg Med Chem Lett; 2005 Feb; 15(4):971-6. PubMed ID: 15686895
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.
    Scozzafava A; Briganti F; Mincione G; Menabuoni L; Mincione F; Supuran CT
    J Med Chem; 1999 Sep; 42(18):3690-700. PubMed ID: 10479300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.
    Güzel O; Innocenti A; Scozzafava A; Salman A; Supuran CT
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3170-3. PubMed ID: 19435663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives.
    Innocenti A; Antel J; Wurl M; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2004 Nov; 14(22):5703-7. PubMed ID: 15482952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
    Saczewski F; Innocenti A; Sławiński J; Kornicka A; Brzozowski Z; Pomarnacka E; Scozzafava A; Temperini C; Supuran CT
    Bioorg Med Chem; 2008 Apr; 16(7):3933-40. PubMed ID: 18242998
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.
    Bozdag M; Ferraroni M; Carta F; Vullo D; Lucarini L; Orlandini E; Rossello A; Nuti E; Scozzafava A; Masini E; Supuran CT
    J Med Chem; 2014 Nov; 57(21):9152-67. PubMed ID: 25310626
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes.
    Carta F; Pothen B; Maresca A; Tiwari M; Singh V; Supuran CT
    Chem Biol Drug Des; 2009 Aug; 74(2):196-202. PubMed ID: 19549076
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.
    Vullo D; Scozzafava A; Pastorekova S; Pastorek J; Supuran CT
    Bioorg Med Chem Lett; 2004 May; 14(9):2351-6. PubMed ID: 15081039
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.
    Güzel O; Innocenti A; Scozzafava A; Salman A; Supuran CT
    Bioorg Med Chem; 2009 Jul; 17(14):4894-9. PubMed ID: 19539481
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating phthaloyl and phthalimido moieties.
    Scozzafava A; Mincione F; Menabuoni L; Supuran CT
    Drug Des Discov; 2001; 17(4):337-48. PubMed ID: 11765137
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
    Carta F; Garaj V; Maresca A; Wagner J; Avvaru BS; Robbins AH; Scozzafava A; McKenna R; Supuran CT
    Bioorg Med Chem; 2011 May; 19(10):3105-19. PubMed ID: 21515057
    [TBL] [Abstract][Full Text] [Related]  

  • 18. QSAR studies for the inhibition of the transmembrane isozymes XII and XIV of human carbonic anhydrase with a series of sulfonamides.
    Tarko L; Supuran CT
    Bioorg Med Chem; 2007 Sep; 15(17):5666-71. PubMed ID: 17574422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols.
    Innocenti A; Hilvo M; Scozzafava A; Parkkila S; Supuran CT
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3593-6. PubMed ID: 18501600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carbonic anhydrase inhibitors. Synthesis of topically effective intraocular pressure lowering agents derived from 5-(omega-aminoalkylcarboxamido)-1,3,4-thiadiazole-2-sulfonamide.
    Barboiu M; Supuran CT; Menabuoni L; Scozzafava A; Mincione F; Briganti F; Mincione G
    J Enzyme Inhib; 2000; 15(1):23-46. PubMed ID: 10850953
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.