These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 16039854)

  • 21. Synthesis and biological evaluation of pyridine-modified analogues of 3-(2-aminoethoxy)pyridine as novel nicotinic receptor ligands.
    Lin NH; Dong L; Bunnelle WH; Anderson DJ; Meyer MD
    Bioorg Med Chem Lett; 2002 Nov; 12(22):3321-4. PubMed ID: 12392742
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hydrogen-bond interactions of nicotine and acetylcholine salts: a combined crystallographic, spectroscopic, thermodynamic and theoretical study.
    Arnaud V; Berthelot M; Evain M; Graton J; Le Questel JY
    Chemistry; 2007; 13(5):1499-510. PubMed ID: 17103466
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development and optimization of a high-throughput electrophysiology assay for neuronal alpha4beta2 nicotinic receptors.
    Sidach SS; Fedorov NB; Lippiello PM; Bencherif M
    J Neurosci Methods; 2009 Aug; 182(1):17-24. PubMed ID: 19481112
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Rigid analogs of DMPP as probes for the nicotinic receptors.
    Guandalini L; Martini E; Martelli C; Romanelli MN; Varani K
    Farmaco; 2005 Feb; 60(2):99-104. PubMed ID: 15752468
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors.
    Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj MI; Martin BR; Glennon RA
    Bioorg Med Chem Lett; 2003 Feb; 13(4):733-5. PubMed ID: 12639569
    [TBL] [Abstract][Full Text] [Related]  

  • 26. alpha4beta2 nACh receptor pharmacophore models.
    Glennon RA; Dukat M
    Bioorg Med Chem Lett; 2004 Apr; 14(8):1841-4. PubMed ID: 15050612
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structural features of phenoxycarbonylimino neonicotinoids acting at the insect nicotinic receptor.
    Ohno I; Tomizawa M; Miyazu N; Kushibiki G; Noda K; Hasebe Y; Durkin KA; Miyake T; Kagabu S
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5933-5. PubMed ID: 20729079
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
    Carroll FI; Hu X; Navarro HA; Deschamps J; Abdrakhmanova GR; Damaj MI; Martin BR
    J Med Chem; 2006 Jun; 49(11):3244-50. PubMed ID: 16722642
    [TBL] [Abstract][Full Text] [Related]  

  • 29. alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine.
    Moroni M; Zwart R; Sher E; Cassels BK; Bermudez I
    Mol Pharmacol; 2006 Aug; 70(2):755-68. PubMed ID: 16720757
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Modelling of full-length human alpha4beta2 nicotinic receptor by fragmental approach and analysis of its binding modes.
    Pedretti A; Marconi C; Bolchi C; Fumagalli L; Ferrara R; Pallavicini M; Valoti E; Vistoli G
    Biochem Biophys Res Commun; 2008 May; 369(2):648-53. PubMed ID: 18302933
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model.
    Tuccinardi T; Schenone S; Bondavalli F; Brullo C; Bruno O; Mosti L; Zizzari AT; Tintori C; Manetti F; Ciampi O; Trincavelli ML; Martini C; Martinelli A; Botta M
    ChemMedChem; 2008 Jun; 3(6):898-913. PubMed ID: 18338422
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis and pharmacological evaluation of some (pyridyl)cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands.
    Guandalini L; Dei S; Manetti D; Romanelli MN; Scapecchi S; Teodori E; Varani K
    Farmaco; 2002 Jun; 57(6):487-96. PubMed ID: 12088064
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding.
    Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj MI; Martin BR; Glennon RA
    J Med Chem; 2002 Oct; 45(21):4724-31. PubMed ID: 12361399
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.
    Bunnelle WH; Daanen JF; Ryther KB; Schrimpf MR; Dart MJ; Gelain A; Meyer MD; Frost JM; Anderson DJ; Buckley M; Curzon P; Cao YJ; Puttfarcken P; Searle X; Ji J; Putman CB; Surowy C; Toma L; Barlocco D
    J Med Chem; 2007 Jul; 50(15):3627-44. PubMed ID: 17585748
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators.
    Albrecht BK; Berry V; Boezio AA; Cao L; Clarkin K; Guo W; Harmange JC; Hierl M; Huang L; Janosky B; Knop J; Malmberg A; McDermott JS; Nguyen HQ; Springer SK; Waldon D; Woodin K; McDonough SI
    Bioorg Med Chem Lett; 2008 Oct; 18(19):5209-12. PubMed ID: 18789861
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors.
    Zwart R; Carbone AL; Moroni M; Bermudez I; Mogg AJ; Folly EA; Broad LM; Williams AC; Zhang D; Ding C; Heinz BA; Sher E
    Mol Pharmacol; 2008 Jun; 73(6):1838-43. PubMed ID: 18367540
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Insights into docking and scoring neuronal alpha4beta2 nicotinic receptor agonists using molecular dynamics simulations and QM/MM calculations.
    Sgrignani J; Bonaccini C; Grazioso G; Chioccioli M; Cavalli A; Gratteri P
    J Comput Chem; 2009 Nov; 30(15):2443-54. PubMed ID: 19360794
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Direct chromatographic determination of dissociation rate constants of ligand-receptor complexes: assessment of the interaction of noncompetitive inhibitors with an immobilized nicotinic acetylcholine receptor-based liquid chromatography stationary phase.
    Moaddel R; Jozwiak K; Yamaguchi R; Wainer IW
    Anal Chem; 2005 Aug; 77(16):5421-6. PubMed ID: 16097790
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pyrazolopyridinones as functionally selective GABAA ligands.
    Blackaby WP; Atack JR; Bromidge F; Lewis R; Russell MG; Smith A; Wafford K; McKernan RM; Street LJ; Castro JL
    Bioorg Med Chem Lett; 2005 Nov; 15(22):4998-5002. PubMed ID: 16153832
    [TBL] [Abstract][Full Text] [Related]  

  • 40. QSAR study of a large set of 3-pyridyl ethers as ligands of the alpha4beta2 nicotinic acetylcholine receptor.
    Zhang H; Li H; Ma Q
    J Mol Graph Model; 2007 Jul; 26(1):226-35. PubMed ID: 17208024
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.