BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 16042416)

  • 1. Combinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptase.
    Somasunderam A; Ferguson MR; Rojo DR; Thiviyanathan V; Li X; O'Brien WA; Gorenstein DG
    Biochemistry; 2005 Aug; 44(30):10388-95. PubMed ID: 16042416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combinatorial selection and delivery of thioaptamers.
    Thiviyanathan V; Somasunderam AD; Gorenstein DG
    Biochem Soc Trans; 2007 Feb; 35(Pt 1):50-2. PubMed ID: 17233599
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity.
    Andreola ML; Pileur F; Calmels C; Ventura M; Tarrago-Litvak L; Toulmé JJ; Litvak S
    Biochemistry; 2001 Aug; 40(34):10087-94. PubMed ID: 11513587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
    Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
    Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.
    Brehm JH; Koontz D; Meteer JD; Pathak V; Sluis-Cremer N; Mellors JW
    J Virol; 2007 Aug; 81(15):7852-9. PubMed ID: 17507476
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).
    Joshi P; Prasad VR
    J Virol; 2002 Jul; 76(13):6545-57. PubMed ID: 12050367
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
    Borkow G; Fletcher RS; Barnard J; Arion D; Motakis D; Dmitrienko GI; Parniak MA
    Biochemistry; 1997 Mar; 36(11):3179-85. PubMed ID: 9115994
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.
    Hisayoshi T; Shinomura M; Yokokawa K; Kuze I; Konishi A; Kawaji K; Kodama EN; Hata K; Takahashi S; Nirasawa S; Sakuda S; Yasukawa K
    J Nat Med; 2015 Jul; 69(3):432-40. PubMed ID: 25663480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.
    Budihas SR; Gorshkova I; Gaidamakov S; Wamiru A; Bona MK; Parniak MA; Crouch RJ; McMahon JB; Beutler JA; Le Grice SF
    Nucleic Acids Res; 2005; 33(4):1249-56. PubMed ID: 15741178
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA aptamers derived from HIV-1 RNase H inhibitors are strong anti-integrase agents.
    de Soultrait VR; Lozach PY; Altmeyer R; Tarrago-Litvak L; Litvak S; Andréola ML
    J Mol Biol; 2002 Nov; 324(2):195-203. PubMed ID: 12441099
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
    Li TK; Barbieri CM; Lin HC; Rabson AB; Yang G; Fan Y; Gaffney BL; Jones RA; Pilch DS
    Biochemistry; 2004 Aug; 43(30):9732-42. PubMed ID: 15274628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
    Tang J; Vernekar SKV; Chen YL; Miller L; Huber AD; Myshakina N; Sarafianos SG; Parniak MA; Wang Z
    Eur J Med Chem; 2017 Jun; 133():85-96. PubMed ID: 28384548
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
    Boyer PL; Smith SJ; Zhao XZ; Das K; Gruber K; Arnold E; Burke TR; Hughes SH
    J Virol; 2018 Jul; 92(13):. PubMed ID: 29643235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
    Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
    PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
    Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
    Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PMTI, a broadly active unusual single-stranded polyribonucleotide, inhibits human immunodeficiency virus replication by multiple mechanisms.
    Buckheit RW; Lackman-Smith C; Snow MJ; Halliday SM; White EL; Ross LJ; Agrawal VK; Broom AD
    Antivir Chem Chemother; 1999 Jan; 10(1):23-32. PubMed ID: 10079876
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
    Wang L; Sarafianos SG; Wang Z
    Acc Chem Res; 2020 Jan; 53(1):218-230. PubMed ID: 31880912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective inhibition of HIV-1 reverse transcriptase (HIV-1 RT) RNase H by small RNA hairpins and dumbbells.
    Hannoush RN; Carriero S; Min KL; Damha MJ
    Chembiochem; 2004 Apr; 5(4):527-33. PubMed ID: 15185377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones.
    Arion D; Sluis-Cremer N; Min KL; Abram ME; Fletcher RS; Parniak MA
    J Biol Chem; 2002 Jan; 277(2):1370-4. PubMed ID: 11684697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiviral activity.
    Ferguson MR; Rojo DR; Somasunderam A; Thiviyanathan V; Ridley BD; Yang X; Gorenstein DG
    Biochem Biophys Res Commun; 2006 Jun; 344(3):792-7. PubMed ID: 16631118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.