BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 16042546)

  • 1. Involvement of presenilins in cell-survival signalling pathways.
    McCarthy JV
    Biochem Soc Trans; 2005 Aug; 33(Pt 4):568-72. PubMed ID: 16042546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilin function and gamma-secretase activity.
    Brunkan AL; Goate AM
    J Neurochem; 2005 May; 93(4):769-92. PubMed ID: 15857382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [beta-amyloid cascade: current status and future directions].
    Iwatsubo T
    Rinsho Shinkeigaku; 2000 Dec; 40(12):1228-30. PubMed ID: 11464463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma-secretase: a catalyst of Alzheimer disease and signal transduction.
    Li YM
    Mol Interv; 2001 Oct; 1(4):198-207. PubMed ID: 14993342
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M; Nyabi O; Verhamme J; Tolia A; Horré K; Wiltfang J; Esselmann H; De Strooper B
    J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Beta-amyloid protein: recent progress in basic research and therapeutic approaches].
    Iwatsubo T
    Rinsho Shinkeigaku; 2001 Dec; 41(12):1198-200. PubMed ID: 12235837
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intramembrane proteolysis by presenilins.
    Steiner H; Haass C
    Nat Rev Mol Cell Biol; 2000 Dec; 1(3):217-24. PubMed ID: 11252897
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice.
    Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; Serneels L; Saftig P; Craessaerts K; De Strooper B; Hartmann D
    Hum Mol Genet; 2004 Jul; 13(13):1321-31. PubMed ID: 15128703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling.
    Landman N; Kim TW
    Cytokine Growth Factor Rev; 2004 Oct; 15(5):337-51. PubMed ID: 15450250
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
    Hoke DE; Tan JL; Ilaya NT; Culvenor JG; Smith SJ; White AR; Masters CL; Evin GM
    FEBS J; 2005 Nov; 272(21):5544-57. PubMed ID: 16262694
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alzheimer's disease. Closing in on gamma-secretase.
    De Strooper B
    Nature; 2000 Jun; 405(6787):627, 629. PubMed ID: 10864307
    [No Abstract]   [Full Text] [Related]  

  • 14. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K; Tomioka M; Kremmer E; Haass C; Steiner H
    Neurobiol Dis; 2007 Jul; 27(1):102-7. PubMed ID: 17560791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.
    Marambaud P; Robakis NK
    Genes Brain Behav; 2005 Apr; 4(3):134-46. PubMed ID: 15810902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation.
    Wang J; Beher D; Nyborg AC; Shearman MS; Golde TE; Goate A
    J Neurochem; 2006 Jan; 96(1):218-27. PubMed ID: 16305624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding partners of Alzheimer's disease proteins: are they physiologically relevant?
    Van Gassen G; Annaert W; Van Broeckhoven C
    Neurobiol Dis; 2000 Jun; 7(3):135-51. PubMed ID: 10860781
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells.
    Alves da Costa C; Ayral E; Hernandez JF; St George-Hyslop P; Checler F
    J Neurochem; 2004 Aug; 90(4):800-6. PubMed ID: 15287885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
    Iwatsubo T
    Rinsho Shinkeigaku; 2004 Nov; 44(11):768-70. PubMed ID: 15651286
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Presenilins as a marker of Alzheimer's disease].
    Scheper W; van Gool WA
    Ned Tijdschr Geneeskd; 1998 May; 142(22):1247-52. PubMed ID: 9749296
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.