223 related articles for article (PubMed ID: 16045439)
1. L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis.
Cunningham GA; McClenaghan NH; Flatt PR; Newsholme P
Clin Sci (Lond); 2005 Nov; 109(5):447-55. PubMed ID: 16045439
[TBL] [Abstract][Full Text] [Related]
2. Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction.
Michalska M; Wolf G; Walther R; Newsholme P
Biosci Rep; 2010 Dec; 30(6):445-53. PubMed ID: 20178457
[TBL] [Abstract][Full Text] [Related]
3. Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic beta-cell line.
Corless M; Kiely A; McClenaghan NH; Flatt PR; Newsholme P
J Endocrinol; 2006 Sep; 190(3):719-27. PubMed ID: 17003273
[TBL] [Abstract][Full Text] [Related]
4. Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway.
Zhang Z; Ding Y; Dai X; Wang J; Li Y
Eur J Pharmacol; 2011 Nov; 670(1):311-6. PubMed ID: 21925162
[TBL] [Abstract][Full Text] [Related]
5. Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line.
Morgan D; Oliveira-Emilio HR; Keane D; Hirata AE; Santos da Rocha M; Bordin S; Curi R; Newsholme P; Carpinelli AR
Diabetologia; 2007 Feb; 50(2):359-69. PubMed ID: 17151863
[TBL] [Abstract][Full Text] [Related]
6. Evidence for a sustained increase in clonal beta-cell basal intracellular Ca2+ levels after incubation in the presence of newly diagnosed Type-1 diabetic patient sera. Possible role in serum-induced inhibition of insulin secretion.
Conroy SJ; Green I; Dixon G; Byrne PM; Nolan J; Abdel-Wahab YH; McClenaghan N; Flatt PR; Newsholme P
J Endocrinol; 2002 Apr; 173(1):53-62. PubMed ID: 11927384
[TBL] [Abstract][Full Text] [Related]
7. L-arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge.
Krause MS; McClenaghan NH; Flatt PR; de Bittencourt PI; Murphy C; Newsholme P
J Endocrinol; 2011 Oct; 211(1):87-97. PubMed ID: 21784771
[TBL] [Abstract][Full Text] [Related]
8. Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line.
Kiely A; McClenaghan NH; Flatt PR; Newsholme P
J Endocrinol; 2007 Oct; 195(1):113-23. PubMed ID: 17911403
[TBL] [Abstract][Full Text] [Related]
9. Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.
Kutlu B; Cardozo AK; Darville MI; Kruhøffer M; Magnusson N; Ørntoft T; Eizirik DL
Diabetes; 2003 Nov; 52(11):2701-19. PubMed ID: 14578289
[TBL] [Abstract][Full Text] [Related]
10. Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells.
Chan JY; Cooney GJ; Biden TJ; Laybutt DR
Diabetologia; 2011 Jul; 54(7):1766-76. PubMed ID: 21472432
[TBL] [Abstract][Full Text] [Related]
11. Costus pictus D. Don leaf extract stimulates GLP-1 secretion from GLUTag L-cells and has cytoprotective effects in BRIN-BD11 β-cells.
Patibandla C; Khan ZI; MacGregor L; Campbell MJ; Patterson S
J Ethnopharmacol; 2020 Oct; 260():112970. PubMed ID: 32422353
[TBL] [Abstract][Full Text] [Related]
12. Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase.
Patterson S; Flatt PR; McClenaghan NH
Pancreas; 2007 Jan; 34(1):144-51. PubMed ID: 17198197
[TBL] [Abstract][Full Text] [Related]
13. Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line.
Keane DC; Takahashi HK; Dhayal S; Morgan NG; Curi R; Newsholme P
Clin Sci (Lond); 2011 Mar; 120(5):195-206. PubMed ID: 20840078
[TBL] [Abstract][Full Text] [Related]
14. The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.
Pavlovic D; Chen MC; Gysemans CA; Mathieu C; Eizirik DL
Eur Cytokine Netw; 1999 Sep; 10(3):403-12. PubMed ID: 10477397
[TBL] [Abstract][Full Text] [Related]
15. Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
Patterson S; Flatt PR; Brennan L; Newsholme P; McClenaghan NH
J Endocrinol; 2006 May; 189(2):301-10. PubMed ID: 16648297
[TBL] [Abstract][Full Text] [Related]
16. Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents.
Patterson S; Scullion SM; McCluskey JT; Flatt PR; McClenaghan NH
Diabetes Metab Res Rev; 2007 May; 23(4):324-34. PubMed ID: 17089371
[TBL] [Abstract][Full Text] [Related]
17. Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.
Størling J; Binzer J; Andersson AK; Züllig RA; Tonnesen M; Lehmann R; Spinas GA; Sandler S; Billestrup N; Mandrup-Poulsen T
Diabetologia; 2005 Oct; 48(10):2039-50. PubMed ID: 16132952
[TBL] [Abstract][Full Text] [Related]
18. Importance of NADPH oxidase-mediated redox signaling in the detrimental effect of CRP on pancreatic insulin secretion.
Chan PC; Wang YC; Chen YL; Hsu WN; Tian YF; Hsieh PS
Free Radic Biol Med; 2017 Nov; 112():200-211. PubMed ID: 28778482
[TBL] [Abstract][Full Text] [Related]
19. Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.
McClenaghan NH; Scullion SM; Mion B; Hewage C; Malthouse JP; Flatt PR; Newsholme P; Brennan L
Clin Sci (Lond); 2009 Feb; 116(4):341-51. PubMed ID: 18702613
[TBL] [Abstract][Full Text] [Related]
20. Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways.
Karlsen AE; Heding PE; Frobøse H; Rønn SG; Kruhøffer M; Orntoft TF; Darville M; Eizirik DL; Pociot F; Nerup J; Mandrup-Poulsen T; Billestrup N
Diabetologia; 2004 Nov; 47(11):1998-2011. PubMed ID: 15578154
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]