These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 16046130)

  • 1. Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor.
    Pontillo J; Guo Z; Wu D; Struthers RS; Chen C
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4363-6. PubMed ID: 16046130
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists.
    Guo Z; Wu D; Zhu YF; Tucci FC; Pontillo J; Saunders J; Xie Q; Struthers RS; Chen C
    Bioorg Med Chem Lett; 2005 Feb; 15(3):693-8. PubMed ID: 15664839
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists.
    Guo Z; Wu D; Zhu YF; Tucci FC; Regan CF; Rowbottom MW; Struthers RS; Xie Q; Reijmers S; Sullivan SK; Sai Y; Chen C
    Bioorg Med Chem Lett; 2005 Aug; 15(16):3685-90. PubMed ID: 15951171
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonists.
    Guo Z; Zhu YF; Gross TD; Tucci FC; Gao Y; Moorjani M; Connors PJ; Rowbottom MW; Chen Y; Struthers RS; Xie Q; Saunders J; Reinhart G; Chen TK; Bonneville AL; Chen C
    J Med Chem; 2004 Feb; 47(5):1259-71. PubMed ID: 14971906
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationships of 8-(pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: potent, orally bioavailable corticotropin releasing factor receptor-1 (CRF1) antagonists.
    Gilligan PJ; Clarke T; He L; Lelas S; Li YW; Heman K; Fitzgerald L; Miller K; Zhang G; Marshall A; Krause C; McElroy JF; Ward K; Zeller K; Wong H; Bai S; Saye J; Grossman S; Zaczek R; Arneric SP; Hartig P; Robertson D; Trainor G
    J Med Chem; 2009 May; 52(9):3084-92. PubMed ID: 19361209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of 1-arylmethyl-3- (2-aminoethyl)-5-aryluracil as novel gonadotropin-releasing hormone receptor antagonists.
    Zhu YF; Gross TD; Guo Z; Connors PJ; Gao Y; Tucci FC; Struthers RS; Reinhart GJ; Saunders J; Chen TK; Killam Bonneville AL; Chen C
    J Med Chem; 2003 May; 46(11):2023-6. PubMed ID: 12747774
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triazine compounds as antagonists at Bv8-prokineticin receptors.
    Balboni G; Lazzari I; Trapella C; Negri L; Lattanzi R; Giannini E; Nicotra A; Melchiorri P; Visentin S; Nuccio CD; Salvadori S
    J Med Chem; 2008 Dec; 51(23):7635-9. PubMed ID: 19006379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Uracils as potent antagonists of the human gonadotropin-releasing hormone receptor without atropisomers.
    Guo Z; Chen Y; Huang CQ; Gross TD; Pontillo J; Rowbottom MW; Saunders J; Struthers S; Tucci FC; Xie Q; Wade W; Zhu YF; Wu D; Chen C
    Bioorg Med Chem Lett; 2005 May; 15(10):2519-22. PubMed ID: 15863308
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor.
    Betz SF; Reinhart GJ; Lio FM; Chen C; Struthers RS
    J Med Chem; 2006 Jan; 49(2):637-47. PubMed ID: 16420049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A multicomponent synthesis of triazinane diones.
    Groenendaal B; Vugts DJ; Schmitz RF; de Kanter FJ; Ruijter E; Groen MB; Orru RV
    J Org Chem; 2008 Jan; 73(2):719-22. PubMed ID: 18095703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Traceless solid-phase synthesis of 6-amino- and 6-hydroxyimino-1,3,5-triazine-2,4-diones and 1,3,5-triazine-2,4,6-triones.
    Kong KH; Tan CK; Lam Y
    J Comb Chem; 2009; 11(6):1050-60. PubMed ID: 19817460
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient synthesis of bicyclic oxazolino- and thiazolino[3,2-c]pyrimidine-5,7-diones and its application to the synthesis of GnRH antagonists.
    Pontillo J; Chen C
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1407-11. PubMed ID: 15713397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selection, synthesis, and structure-activity relationship of tetrahydropyrido[4,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists.
    Lanier MC; Feher M; Ashweek NJ; Loweth CJ; Rueter JK; Slee DH; Williams JP; Zhu YF; Sullivan SK; Brown MS
    Bioorg Med Chem; 2007 Aug; 15(16):5590-603. PubMed ID: 17561404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetics of nonpeptide antagonist binding to the human gonadotropin-releasing hormone receptor: Implications for structure-activity relationships and insurmountable antagonism.
    Sullivan SK; Hoare SR; Fleck BA; Zhu YF; Heise CE; Struthers RS; Crowe PD
    Biochem Pharmacol; 2006 Sep; 72(7):838-49. PubMed ID: 16930559
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.
    Imada T; Cho N; Imaeda T; Hayase Y; Sasaki S; Kasai S; Harada M; Matsumoto H; Endo S; Suzuki N; Furuya S
    J Med Chem; 2006 Jun; 49(13):3809-25. PubMed ID: 16789738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and characterization of novel 1,2,4-triazine derivatives with antiproliferative activity.
    Krauth F; Dahse HM; Rüttinger HH; Frohberg P
    Bioorg Med Chem; 2010 Mar; 18(5):1816-21. PubMed ID: 20153202
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of 1,2,4-triazine derivatives as potential anti-anxiety and anti-inflammatory agents.
    Mullick P; Khan SA; Begum T; Verma S; Kaushik D; Alam O
    Acta Pol Pharm; 2009; 66(4):379-85. PubMed ID: 19702169
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-phenyl-4-piperazinylbenzimidazoles: orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor.
    Pelletier JC; Chengalvala M; Cottom J; Feingold I; Garrick L; Green D; Hauze D; Huselton C; Jetter J; Kao W; Kopf GS; Lundquist JT; Mann C; Mehlmann J; Rogers J; Shanno L; Wrobel J
    Bioorg Med Chem; 2008 Jul; 16(13):6617-40. PubMed ID: 18511284
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and cytotoxic activity of trisubstituted-1,3,5-triazines.
    Arya K; Dandia A
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3298-304. PubMed ID: 17449247
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists.
    Gilligan PJ; He L; Clarke T; Tivitmahaisoon P; Lelas S; Li YW; Heman K; Fitzgerald L; Miller K; Zhang G; Marshall A; Krause C; McElroy J; Ward K; Shen H; Wong H; Grossman S; Nemeth G; Zaczek R; Arneric SP; Hartig P; Robertson DW; Trainor G
    J Med Chem; 2009 May; 52(9):3073-83. PubMed ID: 19361210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.