These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 16046402)

  • 1. Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.
    Grujic M; Braga T; Lukinius A; Eloranta ML; Knight SD; Pejler G; Abrink M
    J Biol Chem; 2005 Sep; 280(39):33411-8. PubMed ID: 16046402
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.
    Sutton VR; Brennan AJ; Ellis S; Danne J; Thia K; Jenkins MR; Voskoboinik I; Pejler G; Johnstone RW; Andrews DM; Trapani JA
    FEBS J; 2016 Mar; 283(5):947-61. PubMed ID: 26756195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.
    Veugelers K; Motyka B; Goping IS; Shostak I; Sawchuk T; Bleackley RC
    Mol Biol Cell; 2006 Feb; 17(2):623-33. PubMed ID: 16280358
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T-cells is dependent on pH.
    Masson D; Peters PJ; Geuze HJ; Borst J; Tschopp J
    Biochemistry; 1990 Dec; 29(51):11229-35. PubMed ID: 2125503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.
    Waterhouse NJ; Sutton VR; Sedelies KA; Ciccone A; Jenkins M; Turner SJ; Bird PI; Trapani JA
    J Cell Biol; 2006 Apr; 173(1):133-44. PubMed ID: 16606695
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
    Metkar SS; Wang B; Aguilar-Santelises M; Raja SM; Uhlin-Hansen L; Podack E; Trapani JA; Froelich CJ
    Immunity; 2002 Mar; 16(3):417-28. PubMed ID: 11911826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of CTL induction by rapamycin: IL-2 rescues granzyme B and perforin expression but only partially restores cytotoxic activity.
    Makrigiannis AP; Hoskin DW
    J Immunol; 1997 Nov; 159(10):4700-7. PubMed ID: 9366393
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.
    Browne KA; Johnstone RW; Jans DA; Trapani JA
    J Biol Chem; 2000 Dec; 275(50):39262-6. PubMed ID: 11050075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells.
    Simon MM; Hausmann M; Tran T; Ebnet K; Tschopp J; ThaHla R; Müllbacher A
    J Exp Med; 1997 Nov; 186(10):1781-6. PubMed ID: 9362539
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes.
    Sobek V; Balkow S; Körner H; Simon MM
    Eur J Immunol; 2002 Sep; 32(9):2490-9. PubMed ID: 12207333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
    Raja SM; Metkar SS; Froelich CJ
    Curr Opin Immunol; 2003 Oct; 15(5):528-32. PubMed ID: 14499261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
    Raja SM; Metkar SS; Höning S; Wang B; Russin WA; Pipalia NH; Menaa C; Belting M; Cao X; Dressel R; Froelich CJ
    J Biol Chem; 2005 May; 280(21):20752-61. PubMed ID: 15788411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis.
    Veugelers K; Motyka B; Frantz C; Shostak I; Sawchuk T; Bleackley RC
    Blood; 2004 May; 103(10):3845-53. PubMed ID: 14739229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.
    Kafrouni MI; Brown GR; Thiele DL
    J Immunol; 2001 Aug; 167(3):1566-74. PubMed ID: 11466378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Murine Thy-1+ dendritic epidermal T cell lines express granule-associated perforin and a family of granzyme molecules.
    Krähenbühl O; Gattesco S; Tschopp J
    Immunobiology; 1992 Apr; 184(4-5):392-401. PubMed ID: 1350566
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection.
    Zelinskyy G; Balkow S; Schimmer S; Schepers K; Simon MM; Dittmer U
    Virology; 2004 Dec; 330(2):365-74. PubMed ID: 15567431
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin.
    Grujic M; Christensen JP; Sørensen MR; Abrink M; Pejler G; Thomsen AR
    J Immunol; 2008 Jul; 181(2):1043-51. PubMed ID: 18606656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.
    Johnson BJ; Costelloe EO; Fitzpatrick DR; Haanen JB; Schumacher TN; Brown LE; Kelso A
    Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2657-62. PubMed ID: 12601154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation.
    Graubert TA; DiPersio JF; Russell JH; Ley TJ
    J Clin Invest; 1997 Aug; 100(4):904-11. PubMed ID: 9259590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Serglycin: the master of the mast cell.
    Rönnberg E; Pejler G
    Methods Mol Biol; 2012; 836():201-17. PubMed ID: 22252637
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.