These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 16046613)

  • 1. Analysis of allosterism in functional assays.
    Ehlert FJ
    J Pharmacol Exp Ther; 2005 Nov; 315(2):740-54. PubMed ID: 16046613
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Screening for positive allosteric modulators: assessment of modulator concentration-response curves as a screening paradigm.
    Langmead CJ
    J Biomol Screen; 2007 Aug; 12(5):668-76. PubMed ID: 17478477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods.
    Ehlert FJ
    Mol Pharmacol; 1988 Feb; 33(2):187-94. PubMed ID: 2828914
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determining the potency and molecular mechanism of action of insurmountable antagonists.
    Kenakin T; Jenkinson S; Watson C
    J Pharmacol Exp Ther; 2006 Nov; 319(2):710-23. PubMed ID: 16857731
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stimulus amplification, efficacy, and the operational model. Part II--ternary complex occupancy mechanisms.
    Trzeciakowski JP
    J Theor Biol; 1999 Jun; 198(3):347-74. PubMed ID: 10366491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue response as a functional discriminator of receptor heterogeneity: effects of mixed receptor populations on Schild regressions.
    Kenakin TP
    Mol Pharmacol; 1992 Apr; 41(4):699-707. PubMed ID: 1569922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of asymmetry of concentration-response curves on the results obtained by the receptorial responsiveness method (RRM): an in silico study.
    Grenczer M; Zsuga J; Majoros L; Pinter A; Kemeny-Beke A; Juhasz B; Tosaki A; Gesztelyi R
    Can J Physiol Pharmacol; 2010 Nov; 88(11):1074-83. PubMed ID: 21076495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantifying biological activity in chemical terms: a pharmacology primer to describe drug effect.
    Kenakin T
    ACS Chem Biol; 2009 Apr; 4(4):249-60. PubMed ID: 19193052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.
    Avlani VA; McLoughlin DJ; Sexton PM; Christopoulos A
    J Pharmacol Exp Ther; 2008 Jun; 325(3):927-34. PubMed ID: 18322151
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantitative analysis of receptor allosterism and its implication for drug discovery.
    Zhang R; Kavana M
    Expert Opin Drug Discov; 2015 Jul; 10(7):763-80. PubMed ID: 25927503
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model.
    van Steeg TJ; Freijer J; Danhof M; de Lange EC
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1234-42. PubMed ID: 18162599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. '7TM receptor allostery: putting numbers to shapeshifting proteins.
    Kenakin TP
    Trends Pharmacol Sci; 2009 Sep; 30(9):460-9. PubMed ID: 19729207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S; Sallés J
    Neuropharmacology; 2009 Feb; 56(2):455-62. PubMed ID: 18951909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The influence of affinity, efficacy, and slope factor on the estimates obtained by the receptorial responsiveness method (RRM): a computer simulation study.
    Grenczer M; Pinter A; Zsuga J; Kemeny-Beke A; Juhasz B; Szodoray P; Tosaki A; Gesztelyi R
    Can J Physiol Pharmacol; 2010 Nov; 88(11):1061-73. PubMed ID: 21076494
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The influence of cooperativity on the determination of dissociation constants: examination of the Cheng-Prusoff equation, the Scatchard analysis, the Schild analysis and related power equations.
    Cheng HC
    Pharmacol Res; 2004 Jul; 50(1):21-40. PubMed ID: 15082026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor.
    Sykes DA; Dowling MR; Charlton SJ
    Mol Pharmacol; 2009 Sep; 76(3):543-51. PubMed ID: 19498041
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Quantitative parameters of drug-receptor interactions and receptor reserves. I. Models I-3-R and I-3-S].
    Wenke M; Lincová D; Foglar R
    Sb Lek; 1991 May; 93(3-4):65-77. PubMed ID: 1853140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changes in the in vitro pharmacodynamic properties of metoprolol in atria isolated from spontaneously hypertensive rats.
    Di Verniero C; Höcht C; Opezzo JA; Taira CA
    Clin Exp Pharmacol Physiol; 2007 Mar; 34(3):161-5. PubMed ID: 17250633
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Z-analysis: a new approach to analyze stimulation curves with intrinsic basal stimulation.
    Hedlund PB; von Euler G
    Biochem Pharmacol; 2005 Jul; 70(1):170-5. PubMed ID: 15899474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.
    Ehlert FJ; Griffin MT
    J Pharmacol Exp Ther; 2008 Jun; 325(3):1039-60. PubMed ID: 18305010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.