These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

565 related articles for article (PubMed ID: 16051635)

  • 1. Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
    Rebel H; Kram N; Westerman A; Banus S; van Kranen HJ; de Gruijl FR
    Carcinogenesis; 2005 Dec; 26(12):2123-30. PubMed ID: 16051635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
    Rebel H; Mosnier LO; Berg RJ; Westerman-de Vries A; van Steeg H; van Kranen HJ; de Gruijl FR
    Cancer Res; 2001 Feb; 61(3):977-83. PubMed ID: 11221893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
    de Vries A; Berg RJ; Wijnhoven S; Westerman A; Wester PW; van Kreijl CF; Capel PJ; de Gruijl FR; van Kranen HJ; van Steeg H
    Oncogene; 1998 Apr; 16(17):2205-12. PubMed ID: 9619829
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: frequent recovery of triplet mutations.
    Ikehata H; Yanase F; Mori T; Nikaido O; Tanaka K; Ono T
    Environ Mol Mutagen; 2007 Jan; 48(1):1-13. PubMed ID: 17163503
    [TBL] [Abstract][Full Text] [Related]  

  • 6. More epidermal p53 patches adjacent to skin carcinomas in renal transplant recipients than in immunocompetent patients: the role of azathioprine.
    de Graaf YG; Rebel H; Elghalbzouri A; Cramers P; Nellen RG; Willemze R; Bouwes Bavinck JN; de Gruijl FR
    Exp Dermatol; 2008 Apr; 17(4):349-55. PubMed ID: 17979968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.
    Ananthaswamy HN; Ouhtit A; Evans RL; Gorny A; Khaskina P; Sands AT; Conti CJ
    Oncogene; 1999 Dec; 18(51):7395-8. PubMed ID: 10602497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.
    Berg RJ; Rebel H; van der Horst GT; van Kranen HJ; Mullenders LH; van Vloten WA; de Gruijl FR
    Cancer Res; 2000 Jun; 60(11):2858-63. PubMed ID: 10850428
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
    Kramata P; Lu YP; Lou YR; Singh RN; Kwon SM; Conney AH
    Cancer Res; 2005 May; 65(9):3577-85. PubMed ID: 15867351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.
    Stout GJ; Oosten Mv; Acherrat FZ; Wit Jd; Vermeij WP; Mullenders LH; Gruijl FR; Backendorf C
    DNA Repair (Amst); 2005 Nov; 4(11):1337-44. PubMed ID: 16182614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice.
    Rebel H; van Steeg H; Beems RB; Schouten R; de Gruijl FR; Terleth C
    Cancer Res; 2002 Mar; 62(5):1338-42. PubMed ID: 11888902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.
    de Waard H; Sonneveld E; de Wit J; Esveldt-van Lange R; Hoeijmakers JH; Vrieling H; van der Horst GT
    DNA Repair (Amst); 2008 Oct; 7(10):1659-69. PubMed ID: 18634906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Frequent recovery of triplet mutations in UVB-exposed skin epidermis of Xpc-knockout mice.
    Ikehata H; Saito Y; Yanase F; Mori T; Nikaido O; Ono T
    DNA Repair (Amst); 2007 Jan; 6(1):82-93. PubMed ID: 17049932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
    de Boer J; van Steeg H; Berg RJ; Garssen J; de Wit J; van Oostrum CT; Beems RB; van der Horst GT; van Kreijl CF; de Gruijl FR; Bootsma D; Hoeijmakers JH; Weeda G
    Cancer Res; 1999 Jul; 59(14):3489-94. PubMed ID: 10416615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.
    van Kranen HJ; Westerman A; Berg RJ; Kram N; van Kreijl CF; Wester PW; de Gruijl FR
    Mutat Res; 2005 Apr; 571(1-2):81-90. PubMed ID: 15748640
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clones of normal keratinocytes and a variety of simultaneously present epidermal neoplastic lesions contain a multitude of p53 gene mutations in a xeroderma pigmentosum patient.
    Williams C; Pontén F; Ahmadian A; Ren ZP; Ling G; Rollman O; Ljung A; Jaspers NG; Uhlén M; Lundeberg J; Pontén J
    Cancer Res; 1998 Jun; 58(11):2449-55. PubMed ID: 9622088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
    Hoogervorst EM; van Oostrom CT; Beems RB; van Benthem J; Gielis S; Vermeulen JP; Wester PW; Vos JG; de Vries A; van Steeg H
    Cancer Res; 2004 Aug; 64(15):5118-26. PubMed ID: 15289314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice.
    Takeuchi S; Nakatsu Y; Nakane H; Murai H; Hirota S; Kitamura Y; Okuyama A; Tanaka K
    Cancer Res; 1998 Feb; 58(4):641-6. PubMed ID: 9485015
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors.
    Cheo DL; Meira LB; Burns DK; Reis AM; Issac T; Friedberg EC
    Cancer Res; 2000 Mar; 60(6):1580-4. PubMed ID: 10749126
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci.
    de Gruijl FR; Rebel H
    Photochem Photobiol; 2008; 84(2):382-7. PubMed ID: 18221455
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.