BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 16054447)

  • 1. The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism.
    Jackson C; Kim HK; Carr PD; Liu JW; Ollis DL
    Biochim Biophys Acta; 2005 Aug; 1752(1):56-64. PubMed ID: 16054447
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis.
    Ely F; Hadler KS; Gahan LR; Guddat LW; Ollis DL; Schenk G
    Biochem J; 2010 Dec; 432(3):565-73. PubMed ID: 20868365
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase.
    Jackson CJ; Foo JL; Kim HK; Carr PD; Liu JW; Salem G; Ollis DL
    J Mol Biol; 2008 Feb; 375(5):1189-96. PubMed ID: 18082180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter.
    Ely F; Pedroso MM; Gahan LR; Ollis DL; Guddat LW; Schenk G
    J Inorg Biochem; 2012 Jan; 106(1):19-22. PubMed ID: 22112835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution.
    Yang H; Carr PD; McLoughlin SY; Liu JW; Horne I; Qiu X; Jeffries CM; Russell RJ; Oakeshott JG; Ollis DL
    Protein Eng; 2003 Feb; 16(2):135-45. PubMed ID: 12676982
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based rational design of a phosphotriesterase.
    Jackson CJ; Weir K; Herlt A; Khurana J; Sutherland TD; Horne I; Easton C; Russell RJ; Scott C; Oakeshott JG
    Appl Environ Microbiol; 2009 Aug; 75(15):5153-6. PubMed ID: 19502439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase.
    Kim J; Tsai PC; Chen SL; Himo F; Almo SC; Raushel FM
    Biochemistry; 2008 Sep; 47(36):9497-504. PubMed ID: 18702530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of substrate orientation on the mechanism of a phosphotriesterase.
    Jackson CJ; Liu JW; Coote ML; Ollis DL
    Org Biomol Chem; 2005 Dec; 3(24):4343-50. PubMed ID: 16327895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site.
    Jackson CJ; Carr PD; Kim HK; Liu JW; Herrald P; Mitić N; Schenk G; Smith CA; Ollis DL
    Biochem J; 2006 Aug; 397(3):501-8. PubMed ID: 16686603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detoxification of organophosphate nerve agents by bacterial phosphotriesterase.
    Ghanem E; Raushel FM
    Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):459-70. PubMed ID: 15982683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans.
    Hawwa R; Larsen SD; Ratia K; Mesecar AD
    J Mol Biol; 2009 Oct; 393(1):36-57. PubMed ID: 19631223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase.
    Carletti E; Jacquamet L; Loiodice M; Rochu D; Masson P; Nachon F
    J Enzyme Inhib Med Chem; 2009 Aug; 24(4):1045-55. PubMed ID: 19548794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Theoretical study of the phosphotriesterase reaction mechanism.
    Chen SL; Fang WH; Himo F
    J Phys Chem B; 2007 Feb; 111(6):1253-5. PubMed ID: 17253743
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
    Xiang DF; Kolb P; Fedorov AA; Meier MM; Fedorov LV; Nguyen TT; Sterner R; Almo SC; Shoichet BK; Raushel FM
    Biochemistry; 2009 Mar; 48(10):2237-47. PubMed ID: 19159332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The reaction mechanism of paraoxon hydrolysis by phosphotriesterase from combined QM/MM simulations.
    Wong KY; Gao J
    Biochemistry; 2007 Nov; 46(46):13352-69. PubMed ID: 17966992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of the binuclear metal center through formation of phosphotriesterase-inhibitor complexes.
    Samples CR; Raushel FM; DeRose VJ
    Biochemistry; 2007 Mar; 46(11):3435-42. PubMed ID: 17315951
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).
    Pedroso MM; Ely F; Mitić N; Carpenter MC; Gahan LR; Wilcox DE; Larrabee JL; Ollis DL; Schenk G
    J Biol Inorg Chem; 2014 Dec; 19(8):1263-75. PubMed ID: 25104333
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for natural lactonase and promiscuous phosphotriesterase activities.
    Elias M; Dupuy J; Merone L; Mandrich L; Porzio E; Moniot S; Rochu D; Lecomte C; Rossi M; Masson P; Manco G; Chabriere E
    J Mol Biol; 2008 Jun; 379(5):1017-28. PubMed ID: 18486146
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme.
    Foo JL; Jackson CJ; Carr PD; Kim HK; Schenk G; Gahan LR; Ollis DL
    Biochem J; 2010 Jul; 429(2):313-21. PubMed ID: 20459397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substitution of the catalytic metal and protein PEGylation enhances activity and stability of bacterial phosphotriesterase.
    Perezgasga L; Sánchez-Sánchez L; Aguila S; Vazquez-Duhalt R
    Appl Biochem Biotechnol; 2012 Mar; 166(5):1236-47. PubMed ID: 22249853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.