277 related articles for article (PubMed ID: 160558)
1. Role of thymidylate synthetase activity in development of methotrexate cytotoxicity.
Moran RG; Mulkins M; Heidelberger C
Proc Natl Acad Sci U S A; 1979 Nov; 76(11):5924-8. PubMed ID: 160558
[TBL] [Abstract][Full Text] [Related]
2. Resistance to methotrexate in thymidylate synthetase-deficient mutants of cultured mouse mammary tumor FM3A cells.
Ayusawa D; Koyama H; Seno T
Cancer Res; 1981 Apr; 41(4):1497-501. PubMed ID: 6452198
[TBL] [Abstract][Full Text] [Related]
3. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
Jackman AL; Alison DL; Calvert AH; Harrap KR
Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731
[TBL] [Abstract][Full Text] [Related]
4. Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
Zhang ZG; Malmberg M; Yin MB; Slocum HK; Rustum YM
Biochem Pharmacol; 1993 Mar; 45(5):1157-64. PubMed ID: 8461045
[TBL] [Abstract][Full Text] [Related]
5. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
Chello PL; McQueen CA; DeAngelis LM; Bertino JR
Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
[TBL] [Abstract][Full Text] [Related]
6. Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717.
Jackman AL; Taylor GA; Calvert AH; Harrap KR
Biochem Pharmacol; 1984 Oct; 33(20):3269-75. PubMed ID: 6487375
[TBL] [Abstract][Full Text] [Related]
7. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
Houghton PJ; Rahman A; Will CL; Dolnick BJ; Houghton JA
Cancer Res; 1992 Feb; 52(3):558-65. PubMed ID: 1732043
[TBL] [Abstract][Full Text] [Related]
8. Predictions of a network thermodynamics computer model relating to the mechanism of methotrexate rescue by 5-formyltetrahydrofolate and to the importance of inhibition of thymidylate synthase by methotrexate-polyglutamates.
White JC
Adv Exp Med Biol; 1983; 163():305-26. PubMed ID: 6193692
[TBL] [Abstract][Full Text] [Related]
9. Human leukemic cells resistant to 5-fluoro-2'-deoxyuridine contain a thymidylate synthetase with lower affinity for nucleotides.
Bapat AR; Zarow C; Danenberg PV
J Biol Chem; 1983 Apr; 258(7):4130-6. PubMed ID: 6220000
[TBL] [Abstract][Full Text] [Related]
10. The role of fluorinated pyrimidine analogues in the induction of the in vitro expression of the fragile X chromosome.
Vandamme B; Liebaers I; Hens L; Bernheim JL; Roobol C
Hum Genet; 1988 Aug; 79(4):341-6. PubMed ID: 2970425
[TBL] [Abstract][Full Text] [Related]
11. Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity in gastrointestinal tumor cells.
Washtien WL
Mol Pharmacol; 1982 May; 21(3):723-8. PubMed ID: 6213845
[TBL] [Abstract][Full Text] [Related]
12. Thymidylate synthetase-deficient mouse FM3A mammary carcinoma cell line as a tool for studying the thymidine salvage pathway and the incorporation of thymidine analogues into host cell DNA.
Balzarini J; De Clercq E; Ayusawa D; Seno T
Biochem J; 1984 Jan; 217(1):245-52. PubMed ID: 6696722
[TBL] [Abstract][Full Text] [Related]
13. Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil.
Danhauser LL; Heimer R; Cadman E
Cancer Chemother Pharmacol; 1985; 15(3):214-9. PubMed ID: 3876889
[TBL] [Abstract][Full Text] [Related]
14. Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells.
Balzarini J; De Clercq E
Biochim Biophys Acta; 1984 Feb; 785(1-2):36-45. PubMed ID: 6696920
[TBL] [Abstract][Full Text] [Related]
15. Dissociation of thymidylate biosynthesis from DNA biosynthesis by 5-fluoro-2'-deoxyuridine and 5,8-dideazaisofolic acid.
Fernandes DJ; Cranford SK
Cancer Res; 1986 Apr; 46(4 Pt 1):1741-7. PubMed ID: 2936450
[TBL] [Abstract][Full Text] [Related]
16. Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.
Bonney RJ; Maley F
Cancer Res; 1975 Aug; 35(8):1950-6. PubMed ID: 1170938
[TBL] [Abstract][Full Text] [Related]
17. Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance.
Schuetz JD; Gorse KM; Goldman ID; Westin EH
J Biol Chem; 1988 Jun; 263(16):7708-12. PubMed ID: 2967290
[TBL] [Abstract][Full Text] [Related]
18. 5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.
Fernandes DJ; Bertino JR
Proc Natl Acad Sci U S A; 1980 Oct; 77(10):5663-7. PubMed ID: 6160578
[TBL] [Abstract][Full Text] [Related]
19. Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines.
McGuire JJ; Canestrari JG; Nagel GS
Int J Oncol; 1999 Dec; 15(6):1245-50. PubMed ID: 10568835
[TBL] [Abstract][Full Text] [Related]
20. Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells.
Jackson RC; Jackman AL; Calvert AH
Biochem Pharmacol; 1983 Dec; 32(24):3783-90. PubMed ID: 6661252
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
