217 related articles for article (PubMed ID: 16060664)
1. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells.
Bunik VI; Denton TT; Xu H; Thompson CM; Cooper AJ; Gibson GE
Biochemistry; 2005 Aug; 44(31):10552-61. PubMed ID: 16060664
[TBL] [Abstract][Full Text] [Related]
2. Consequences of the α-ketoglutarate dehydrogenase inhibition for neuronal metabolism and survival: implications for neurodegenerative diseases.
Trofimova LK; Araújo WL; Strokina AA; Fernie AR; Bettendorff L; Bunik VI
Curr Med Chem; 2012; 19(34):5895-906. PubMed ID: 23061627
[TBL] [Abstract][Full Text] [Related]
3. alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ.
Zündorf G; Kahlert S; Bunik VI; Reiser G
Neuroscience; 2009 Jan; 158(2):610-6. PubMed ID: 18996448
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons.
Santos SS; Gibson GE; Cooper AJ; Denton TT; Thompson CM; Bunik VI; Alves PM; Sonnewald U
J Neurosci Res; 2006 Feb; 83(3):450-8. PubMed ID: 16416424
[TBL] [Abstract][Full Text] [Related]
5. Succinyl phosphonate inhibits alpha-ketoglutarate oxidative decarboxylation, catalyzed by alpha-ketoglutarate dehydrogenase complexes from E. coli and pigeon breast muscle.
Biryukov AI; Bunik VI; Zhukov YN; Khurs EN; Khomutov RM
FEBS Lett; 1996 Mar; 382(1-2):167-70. PubMed ID: 8612743
[TBL] [Abstract][Full Text] [Related]
6. Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors.
Lai JC; Cooper AJ
J Neurochem; 1986 Nov; 47(5):1376-86. PubMed ID: 3760866
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation.
Huang HM; Zhang H; Xu H; Gibson GE
Biochim Biophys Acta; 2003 Jan; 1637(1):119-26. PubMed ID: 12527416
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of pigeon breast muscle alpha-ketoglutarate dehydrogenase by phosphonate analogues of alpha-ketoglutarate.
Bunik VI; Biryukov AI; Zhukov YuN
FEBS Lett; 1992 Jun; 303(2-3):197-201. PubMed ID: 1607019
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation,
Araújo WL; Nunes-Nesi A; Trenkamp S; Bunik VI; Fernie AR
Plant Physiol; 2008 Dec; 148(4):1782-96. PubMed ID: 18842826
[TBL] [Abstract][Full Text] [Related]
10. Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons.
Kabysheva MS; Storozhevykh TP; Pinelis VG; Bunik VI
Biochem Pharmacol; 2009 May; 77(9):1531-40. PubMed ID: 19426691
[TBL] [Abstract][Full Text] [Related]
11. Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases.
Denton TT; Thompson CM; Cooper AJ
Anal Biochem; 2001 Nov; 298(2):265-74. PubMed ID: 11700982
[TBL] [Abstract][Full Text] [Related]
12. Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease.
Banerjee K; Munshi S; Xu H; Frank DE; Chen HL; Chu CT; Yang J; Cho S; Kagan VE; Denton TT; Tyurina YY; Jiang JF; Gibson GE
Neurochem Int; 2016 Jun; 96():32-45. PubMed ID: 26923918
[TBL] [Abstract][Full Text] [Related]
13. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines.
Gibson GE; Xu H; Chen HL; Chen W; Denton TT; Zhang S
J Neurochem; 2015 Jul; 134(1):86-96. PubMed ID: 25772995
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.
Huang HM; Ou HC; Xu H; Chen HL; Fowler C; Gibson GE
J Neurosci Res; 2003 Oct; 74(2):309-17. PubMed ID: 14515360
[TBL] [Abstract][Full Text] [Related]
15. Quantitative alpha-ketoglutarate dehydrogenase activity staining in brain sections and in cultured cells.
Park LC; Calingasan NY; Sheu KF; Gibson GE
Anal Biochem; 2000 Jan; 277(1):86-93. PubMed ID: 10610692
[TBL] [Abstract][Full Text] [Related]
16. Phosphonate analog of 2-oxoglutarate regulates glutamate-glutamine homeostasis and counteracts amyloid beta induced learning and memory deficits in rats.
Sayehmiri F; Khodagholi F; Pourbadie HG; Naderi N; Aliakbarzadeh F; Hashemi R; Naderi S; Motamedi F
Exp Gerontol; 2022 Oct; 168():111944. PubMed ID: 36064157
[TBL] [Abstract][Full Text] [Related]
17. Parapyruvate, an Impurity in Pyruvate Supplements, Induces Senescence in Human Fibroblastic Hs68 Cells via Inhibition of the α-Ketoglutarate Dehydrogenase Complex.
Chang SC; Lee I; Ting H; Chang YJ; Yang NC
J Agric Food Chem; 2018 Jul; 66(28):7504-7513. PubMed ID: 29931974
[TBL] [Abstract][Full Text] [Related]
18. Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease.
Sheu KF; Cooper AJ; Koike K; Koike M; Lindsay JG; Blass JP
Ann Neurol; 1994 Mar; 35(3):312-8. PubMed ID: 8122883
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of pigeon breast muscle alpha-ketoglutarate dehydrogenase by structural analogs of alpha-ketoglutarate.
Bunik VI; Pavlova OG
Biochemistry (Mosc); 1997 Sep; 62(9):1012-20. PubMed ID: 9527443
[TBL] [Abstract][Full Text] [Related]
20. Normal glutamate metabolism in Alzheimer's disease fibroblasts deficient in alpha-ketoglutarate dehydrogenase complex activity.
Cooper AL; Sheu KF; Blass JP
Dev Neurosci; 1996; 18(5-6):499-504. PubMed ID: 8940624
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
