129 related articles for article (PubMed ID: 16060665)
21. Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
Muchmore SW; Smith RA; Stewart AO; Cowart MD; Gomtsyan A; Matulenko MA; Yu H; Severin JM; Bhagwat SS; Lee CH; Kowaluk EA; Jarvis MF; Jakob CL
J Med Chem; 2006 Nov; 49(23):6726-31. PubMed ID: 17154503
[TBL] [Abstract][Full Text] [Related]
22. Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Da Settimo F; Primofiore G; La Motta C; Taliani S; Simorini F; Marini AM; Mugnaini L; Lavecchia A; Novellino E; Tuscano D; Martini C
J Med Chem; 2005 Aug; 48(16):5162-74. PubMed ID: 16078836
[TBL] [Abstract][Full Text] [Related]
23. Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Huth JR; Park C; Petros AM; Kunzer AR; Wendt MD; Wang X; Lynch CL; Mack JC; Swift KM; Judge RA; Chen J; Richardson PL; Jin S; Tahir SK; Matayoshi ED; Dorwin SA; Ladror US; Severin JM; Walter KA; Bartley DM; Fesik SW; Elmore SW; Hajduk PJ
Chem Biol Drug Des; 2007 Jul; 70(1):1-12. PubMed ID: 17630989
[TBL] [Abstract][Full Text] [Related]
24. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.
Xu Y; Nakajima Y; Ito K; Zheng H; Oyama H; Heiser U; Hoffmann T; Gärtner UT; Demuth HU; Yoshimoto T
J Mol Biol; 2008 Jan; 375(3):708-19. PubMed ID: 18042490
[TBL] [Abstract][Full Text] [Related]
25. Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors.
Fischmann TO; Smith CK; Mayhood TW; Myers JE; Reichert P; Mannarino A; Carr D; Zhu H; Wong J; Yang RS; Le HV; Madison VS
Biochemistry; 2009 Mar; 48(12):2661-74. PubMed ID: 19161339
[TBL] [Abstract][Full Text] [Related]
26. On the structure-based design of novel inhibitors of H5N1 influenza A virus neuraminidase (NA).
Mitrasinovic PM
Biophys Chem; 2009 Mar; 140(1-3):35-8. PubMed ID: 19117662
[TBL] [Abstract][Full Text] [Related]
27. Structural prediction of peptides binding to MHC class I molecules.
Bui HH; Schiewe AJ; von Grafenstein H; Haworth IS
Proteins; 2006 Apr; 63(1):43-52. PubMed ID: 16447245
[TBL] [Abstract][Full Text] [Related]
28. Binding interaction analysis of the active site and its inhibitors for neuraminidase (N1 subtype) of human influenza virus by the integration of molecular docking, FMO calculation and 3D-QSAR CoMFA modeling.
Zhang Q; Yang J; Liang K; Feng L; Li S; Wan J; Xu X; Yang G; Liu D; Yang S
J Chem Inf Model; 2008 Sep; 48(9):1802-12. PubMed ID: 18707092
[TBL] [Abstract][Full Text] [Related]
29. T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition.
Heng S; Stieglitz KA; Eldo J; Xia J; Cardia JP; Kantrowitz ER
Biochemistry; 2006 Aug; 45(33):10062-71. PubMed ID: 16906764
[TBL] [Abstract][Full Text] [Related]
30. Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.
Schuetz A; Min J; Antoshenko T; Wang CL; Allali-Hassani A; Dong A; Loppnau P; Vedadi M; Bochkarev A; Sternglanz R; Plotnikov AN
Structure; 2007 Mar; 15(3):377-89. PubMed ID: 17355872
[TBL] [Abstract][Full Text] [Related]
31. Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.
Elowe NH; Nutiu R; Allali-Hassani A; Cechetto JD; Hughes DW; Li Y; Brown ED
Angew Chem Int Ed Engl; 2006 Aug; 45(34):5648-52. PubMed ID: 16856187
[No Abstract] [Full Text] [Related]
32. Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies.
Shu Q; Frieden C
J Mol Biol; 2005 Jan; 345(3):599-610. PubMed ID: 15581901
[TBL] [Abstract][Full Text] [Related]
33. Kinetic and conformational studies of adenosine deaminase upon interaction with oxazepam and lorazepam.
Moosavi-Movahedi AA; Sepassi Tehrani H; Amanlou M; Soltani Rad MN; Hakimelahi GH; Tsai FY; Ataie G; Saboury AA; Ahmad F; Khalafi-Nezhad A; Poursasan N; Sharifizadeh A
Protein Pept Lett; 2010 Feb; 17(2):197-205. PubMed ID: 20214645
[TBL] [Abstract][Full Text] [Related]
34. The assignment of downfield proton resonances in an enzyme inhibitor complex using time-dependent saturation transferred NOEs.
Deng H; Cahill S; Kurz L; Callender R
J Am Chem Soc; 2004 Feb; 126(7):1952-3. PubMed ID: 14971925
[TBL] [Abstract][Full Text] [Related]
35. Advances in glycogen phosphorylase inhibitor design.
Oikonomakos NG; Somsák L
Curr Opin Investig Drugs; 2008 Apr; 9(4):379-95. PubMed ID: 18393105
[TBL] [Abstract][Full Text] [Related]
36. Alternative conformation induced by substrate binding for Arabidopsis thalianaN6-methyl-AMP deaminase.
Jia Q; Xie W
Nucleic Acids Res; 2019 Apr; 47(6):3233-3243. PubMed ID: 30721978
[TBL] [Abstract][Full Text] [Related]
37. Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
Rigden DJ; Botzki A; Nukui M; Mewbourne RB; Lamani E; Braun S; von Angerer E; Bernhardt G; Dove S; Buschauer A; Jedrzejas MJ
Glycobiology; 2006 Aug; 16(8):757-65. PubMed ID: 16638841
[TBL] [Abstract][Full Text] [Related]
38. A molecular dynamics study comparing a wild-type with a multiple drug resistant HIV protease: differences in flap and aspartate 25 cavity dimensions.
Seibold SA; Cukier RI
Proteins; 2007 Nov; 69(3):551-65. PubMed ID: 17623840
[TBL] [Abstract][Full Text] [Related]
39. Inhibition of adenosine deaminase by novel 5:7 fused heterocycles containing the imidazo[4,5-e][1,2,4]triazepine ring system: a structure-activity relationship study.
Reayi A; Hosmane RS
J Med Chem; 2004 Feb; 47(4):1044-50. PubMed ID: 14761206
[TBL] [Abstract][Full Text] [Related]
40. Dissecting the catalytic mechanism of a plant beta-D-glucan glucohydrolase through structural biology using inhibitors and substrate analogues.
Hrmova M; Fincher GB
Carbohydr Res; 2007 Sep; 342(12-13):1613-23. PubMed ID: 17548065
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
