206 related articles for article (PubMed ID: 16075413)
21. In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
Zielske SP; Reese JS; Lingas KT; Donze JR; Gerson SL
J Clin Invest; 2003 Nov; 112(10):1561-70. PubMed ID: 14617757
[TBL] [Abstract][Full Text] [Related]
22. Dual repair modulation reverses Temozolomide resistance in vitro.
Barvaux VA; Ranson M; Brown R; McElhinney RS; McMurry TB; Margison GP
Mol Cancer Ther; 2004 Feb; 3(2):123-7. PubMed ID: 14985452
[TBL] [Abstract][Full Text] [Related]
23. Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro.
Hickson I; Fairbairn LJ; Chinnasamy N; Lashford LS; Thatcher N; Margison GP; Dexter TM; Rafferty JA
Gene Ther; 1998 Jun; 5(6):835-41. PubMed ID: 9747464
[TBL] [Abstract][Full Text] [Related]
24. Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.
Phaltane R; Lachmann N; Brennig S; Ackermann M; Modlich U; Moritz T
Biomaterials; 2014 Aug; 35(25):7204-13. PubMed ID: 24875758
[TBL] [Abstract][Full Text] [Related]
25. In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
Larochelle A; Choi U; Shou Y; Naumann N; Loktionova NA; Clevenger JR; Krouse A; Metzger M; Donahue RE; Kang E; Stewart C; Persons D; Malech HL; Dunbar CE; Sorrentino BP
J Clin Invest; 2009 Jul; 119(7):1952-63. PubMed ID: 19509470
[TBL] [Abstract][Full Text] [Related]
26. Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase.
Chinnasamy N; Rafferty JA; Hickson I; Lashford LS; Longhurst SJ; Thatcher N; Margison GP; Dexter TM; Fairbairn LJ
Gene Ther; 1998 Jun; 5(6):842-7. PubMed ID: 9747465
[TBL] [Abstract][Full Text] [Related]
27. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
Maze R; Kurpad C; Pegg AE; Erickson LC; Williams DA
J Pharmacol Exp Ther; 1999 Sep; 290(3):1467-74. PubMed ID: 10454526
[TBL] [Abstract][Full Text] [Related]
28. Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
Chakravarti A; Erkkinen MG; Nestler U; Stupp R; Mehta M; Aldape K; Gilbert MR; Black PM; Loeffler JS
Clin Cancer Res; 2006 Aug; 12(15):4738-46. PubMed ID: 16899625
[TBL] [Abstract][Full Text] [Related]
29. Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.
Hansen RJ; Nagasubramanian R; Delaney SM; Samson LD; Dolan ME
Carcinogenesis; 2007 May; 28(5):1111-6. PubMed ID: 17116724
[TBL] [Abstract][Full Text] [Related]
30. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
Aghi M; Rabkin S; Martuza RL
J Natl Cancer Inst; 2006 Jan; 98(1):38-50. PubMed ID: 16391370
[TBL] [Abstract][Full Text] [Related]
31. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Liu L; Schwartz S; Davis BM; Gerson SL
Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
[TBL] [Abstract][Full Text] [Related]
32. Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
Davis BM; Reese JS; Lingas K; Gerson SL
J Hematother Stem Cell Res; 2003 Aug; 12(4):375-87. PubMed ID: 12965075
[TBL] [Abstract][Full Text] [Related]
33. Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.
Chinnasamy D; Fairbairn LJ; Neuenfeldt J; Treisman JS; Hanson JP; Margison GP; Chinnasamy N
Hum Gene Ther; 2004 Aug; 15(8):758-69. PubMed ID: 15319033
[TBL] [Abstract][Full Text] [Related]
34. G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.
Lee K; Gerson SL; Maitra B; Koç ON
J Hematother Stem Cell Res; 2001 Oct; 10(5):691-701. PubMed ID: 11672516
[TBL] [Abstract][Full Text] [Related]
35. Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma.
Wagner LM; McLendon RE; Yoon KJ; Weiss BD; Billups CA; Danks MK
Clin Cancer Res; 2007 Sep; 13(18 Pt 1):5418-25. PubMed ID: 17875772
[TBL] [Abstract][Full Text] [Related]
36. Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
Reese JS; Roth JC; Gerson SL
Stem Cells; 2008 Mar; 26(3):675-81. PubMed ID: 18192231
[TBL] [Abstract][Full Text] [Related]
37. Clinical relevance of MGMT in the treatment of cancer.
Gerson SL
J Clin Oncol; 2002 May; 20(9):2388-99. PubMed ID: 11981013
[TBL] [Abstract][Full Text] [Related]
38. SarCNU mediates selection of P140K methylguanine-DNA-methyltransferase transduced human CD34(+) cells in vitro.
Zielske SP; Gerson SL
Blood Cells Mol Dis; 2003; 31(1):48-50. PubMed ID: 12850483
[TBL] [Abstract][Full Text] [Related]
39. A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells.
Senhaji Mouhri Z; Goodfellow E; Jean-Claude B
BMC Cancer; 2017 Aug; 17(1):540. PubMed ID: 28800752
[TBL] [Abstract][Full Text] [Related]
40. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]