These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 16084398)

  • 1. Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: a single zinc metalloenzyme.
    Huang KF; Liu YL; Wang AH
    Protein Expr Purif; 2005 Sep; 43(1):65-72. PubMed ID: 16084398
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.
    Schilling S; Lindner C; Koch B; Wermann M; Rahfeld JU; von Bohlen A; Rudolph T; Reuter G; Demuth HU
    Biochemistry; 2007 Sep; 46(38):10921-30. PubMed ID: 17722885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.
    Schilling S; Cynis H; von Bohlen A; Hoffmann T; Wermann M; Heiser U; Buchholz M; Zunkel K; Demuth HU
    Biochemistry; 2005 Oct; 44(40):13415-24. PubMed ID: 16201766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.
    Schilling S; Stenzel I; von Bohlen A; Wermann M; Schulz K; Demuth HU; Wasternack C
    Biol Chem; 2007 Feb; 388(2):145-53. PubMed ID: 17261077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.
    Stephan A; Wermann M; von Bohlen A; Koch B; Cynis H; Demuth HU; Schilling S
    FEBS J; 2009 Nov; 276(22):6522-36. PubMed ID: 19804409
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions.
    Schilling S; Hoffmann T; Manhart S; Hoffmann M; Demuth HU
    FEBS Lett; 2004 Apr; 563(1-3):191-6. PubMed ID: 15063747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glutaminyl cyclase activity is a characteristic feature of human cerebrospinal fluid.
    Gontsarova A; Kaufmann E; Tumani H; Dressel A; Mandel F; Wiesmüller KH; Kunert-Keil C; Brinkmeier H
    Clin Chim Acta; 2008 Mar; 389(1-2):152-9. PubMed ID: 18187042
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloidogenic processing of amyloid precursor protein: evidence of a pivotal role of glutaminyl cyclase in generation of pyroglutamate-modified amyloid-beta.
    Cynis H; Scheel E; Saido TC; Schilling S; Demuth HU
    Biochemistry; 2008 Jul; 47(28):7405-13. PubMed ID: 18570439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Snake venom glutaminyl cyclases: purification, cloning, kinetic study, recombinant expression, and comparison with the human enzyme.
    Wang YM; Huang KF; Tsai IH
    Toxicon; 2014 Aug; 86():40-50. PubMed ID: 24814012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.
    Ruiz-Carrillo D; Koch B; Parthier C; Wermann M; Dambe T; Buchholz M; Ludwig HH; Heiser U; Rahfeld JU; Stubbs MT; Schilling S; Demuth HU
    Biochemistry; 2011 Jul; 50(28):6280-8. PubMed ID: 21671571
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
    Huang KF; Wang YR; Chang EC; Chou TL; Wang AH
    Biochem J; 2008 Apr; 411(1):181-90. PubMed ID: 18072935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity.
    Schilling S; Hoffmann T; Rosche F; Manhart S; Wasternack C; Demuth HU
    Biochemistry; 2002 Sep; 41(35):10849-57. PubMed ID: 12196024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris.
    Huang WL; Wang YR; Ko TP; Chia CY; Huang KF; Wang AH
    J Mol Biol; 2010 Aug; 401(3):374-88. PubMed ID: 20558177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human pituitary glutaminyl cyclase: expression in insect cells and dye affinity purification.
    Booth RE; Misquitta SA; Bateman RC
    Protein Expr Purif; 2003 Nov; 32(1):141-6. PubMed ID: 14680951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding.
    Huang KF; Hsu HL; Karim S; Wang AH
    Acta Crystallogr D Biol Crystallogr; 2014 Mar; 70(Pt 3):789-801. PubMed ID: 24598748
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site.
    Booth RE; Lovell SC; Misquitta SA; Bateman RC
    BMC Biol; 2004 Feb; 2():2. PubMed ID: 15028118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship.
    Buchholz M; Heiser U; Schilling S; Niestroj AJ; Zunkel K; Demuth HU
    J Med Chem; 2006 Jan; 49(2):664-77. PubMed ID: 16420052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of papaya glutaminyl cyclase, an archetype for plant and bacterial glutaminyl cyclases.
    Wintjens R; Belrhali H; Clantin B; Azarkan M; Bompard C; Baeyens-Volant D; Looze Y; Villeret V
    J Mol Biol; 2006 Mar; 357(2):457-70. PubMed ID: 16438985
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
    Cynis H; Rahfeld JU; Stephan A; Kehlen A; Koch B; Wermann M; Demuth HU; Schilling S
    J Mol Biol; 2008 Jun; 379(5):966-80. PubMed ID: 18486145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.
    Koch B; Buchholz M; Wermann M; Heiser U; Schilling S; Demuth HU
    Chem Biol Drug Des; 2012 Dec; 80(6):937-46. PubMed ID: 22967026
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.