These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 16084722)

  • 1. Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors.
    Shreder KR; Wong MS; Corral S; Yu Z; Winn DT; Wu M; Hu Y; Nomanbhoy T; Alemayehu S; Fuller SR; Rosenblum JS; Kozarich JW
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4256-60. PubMed ID: 16084722
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7.
    Hu Y; Ma L; Wu M; Wong MS; Li B; Corral S; Yu Z; Nomanbhoy T; Alemayehu S; Fuller SR; Rosenblum JS; Rozenkrants N; Minimo LC; Ripka WC; Szardenings AK; Kozarich JW; Shreder KR
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4239-42. PubMed ID: 16085416
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.
    Wu W; Liu Y; Milo LJ; Shu Y; Zhao P; Li Y; Woznica I; Yu G; Sanford DG; Zhou Y; Poplawski SE; Connolly BA; Sudmeier JL; Bachovchin WW; Lai JH
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5536-40. PubMed ID: 22853995
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of boronic acid inhibitors of dipeptidyl peptidase IV. 1. Variation of the P2 position of Xaa-boroPro dipeptides.
    Coutts SJ; Kelly TA; Snow RJ; Kennedy CA; Barton RW; Adams J; Krolikowski DA; Freeman DM; Campbell SJ; Ksiazek JF; Bachovchin WW
    J Med Chem; 1996 May; 39(10):2087-94. PubMed ID: 8642568
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Docking-based 3D-QSAR study for selectivity of DPP4, DPP8, and DPP9 inhibitors.
    Kang NS; Ahn JH; Kim SS; Chae CH; Yoo SE
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3716-21. PubMed ID: 17462890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads.
    Van der Veken P; De Meester I; Dubois V; Soroka A; Van Goethem S; Maes MB; Brandt I; Lambeir AM; Chen X; Haemers A; Scharpé S; Augustyns K
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4154-8. PubMed ID: 18556199
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors.
    Van Goethem S; Van der Veken P; Dubois V; Soroka A; Lambeir AM; Chen X; Haemers A; Scharpé S; De Meester I; Augustyns K
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4159-62. PubMed ID: 18556198
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety.
    Connolly BA; Sanford DG; Chiluwal AK; Healey SE; Peters DE; Dimare MT; Wu W; Liu Y; Maw H; Zhou Y; Li Y; Jin Z; Sudmeier JL; Lai JH; Bachovchin WW
    J Med Chem; 2008 Oct; 51(19):6005-13. PubMed ID: 18783201
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases.
    Senten K; Van der Veken P; De Meester I; Lambeir AM; Scharpé S; Haemers A; Augustyns K
    J Med Chem; 2003 Nov; 46(23):5005-14. PubMed ID: 14584950
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein.
    Tsai TY; Yeh TK; Chen X; Hsu T; Jao YC; Huang CH; Song JS; Huang YC; Chien CH; Chiu JH; Yen SC; Tang HK; Chao YS; Jiaang WT
    J Med Chem; 2010 Sep; 53(18):6572-83. PubMed ID: 20718420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.
    Lu IL; Lee SJ; Tsu H; Wu SY; Kao KH; Chien CH; Chang YY; Chen YS; Cheng JH; Chang CN; Chen TW; Chang SP; Chen X; Jiaang WT
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3271-5. PubMed ID: 15927466
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?
    Van Goethem S; Matheeussen V; Joossens J; Lambeir AM; Chen X; De Meester I; Haemers A; Augustyns K; Van der Veken P
    J Med Chem; 2011 Aug; 54(16):5737-46. PubMed ID: 21711053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases.
    Senten K; Daniëls L; Van der Veken P; De Meester I; Lambeir AM; Scharpé S; Haemers A; Augustyns K
    J Comb Chem; 2003; 5(3):336-44. PubMed ID: 12739951
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.
    Bezerra GA; Dobrovetsky E; Dong A; Seitova A; Crombett L; Shewchuk LM; Hassell AM; Sweitzer SM; Sweitzer TD; McDevitt PJ; Johanson KO; Kennedy-Wilson KM; Cossar D; Bochkarev A; Gruber K; Dhe-Paganon S
    PLoS One; 2012; 7(8):e43019. PubMed ID: 22952628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors.
    Huan Y; Jiang Q; Liu JL; Shen ZF
    J Pharmacol Toxicol Methods; 2015; 71():8-12. PubMed ID: 25464020
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expanded substrate specificity supported by P1' and P2' residues enables bacterial dipeptidyl-peptidase 7 to degrade bioactive peptides.
    Ohara-Nemoto Y; Shimoyama Y; Ono T; Sarwar MT; Nakasato M; Sasaki M; Nemoto TK
    J Biol Chem; 2022 Mar; 298(3):101585. PubMed ID: 35032549
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, biological evaluation, and structure-activity relationship (SAR) discussion of dipeptidyl boronate proteasome inhibitors, part I: comprehensive understanding of the SAR of alpha-amino acid boronates.
    Zhu Y; Zhao X; Zhu X; Wu G; Li Y; Ma Y; Yuan Y; Yang J; Hu Y; Ai L; Gao Q
    J Med Chem; 2009 Jul; 52(14):4192-9. PubMed ID: 19537716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates.
    Van der Veken P; Soroka A; Brandt I; Chen YS; Maes MB; Lambeir AM; Chen X; Haemers A; Scharpé S; Augustyns K; De Meester I
    J Med Chem; 2007 Nov; 50(23):5568-70. PubMed ID: 17958345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C.
    Guay D; Beaulieu C; Truchon JF; Jagadeeswar Reddy T; Zamboni R; Bayly CI; Methot N; Rubin J; Ethier D; David Percival M
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5392-6. PubMed ID: 19665376
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bicyclic cyanothiazolidines as novel dipeptidyl peptidase 4 inhibitors.
    Betancort JM; Winn DT; Liu R; Xu Q; Liu J; Liao W; Chen SH; Carney D; Hanway D; Schmeits J; Li X; Gordon E; Campbell DA
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4437-40. PubMed ID: 19482472
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.