BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 16087682)

  • 41. Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazone.
    McKay NG; Kinsella JM; Campbell CM; Ashford ML
    Br J Pharmacol; 2000 Jun; 130(4):857-66. PubMed ID: 10864893
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.
    Cui Y; Tinker A; Clapp LH
    Br J Pharmacol; 2003 May; 139(1):122-8. PubMed ID: 12746230
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Differences in the mechanism of metabolic regulation of ATP-sensitive K+ channels containing Kir6.1 and Kir6.2 subunits.
    Farzaneh T; Tinker A
    Cardiovasc Res; 2008 Sep; 79(4):621-31. PubMed ID: 18522960
    [TBL] [Abstract][Full Text] [Related]  

  • 44. A mutation in the TMD0-L0 region of sulfonylurea receptor-1 (L225P) causes permanent neonatal diabetes mellitus (PNDM).
    Masia R; De Leon DD; MacMullen C; McKnight H; Stanley CA; Nichols CG
    Diabetes; 2007 May; 56(5):1357-62. PubMed ID: 17317760
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Uncoupling by (--)-epigallocatechin-3-gallate of ATP-sensitive potassium channels from phosphatidylinositol polyphosphates and ATP.
    Jin JY; Park SH; Bae JH; Cho HC; Lim JG; Park WS; Han J; Lee JH; Song DK
    Pharmacol Res; 2007 Sep; 56(3):237-47. PubMed ID: 17656102
    [TBL] [Abstract][Full Text] [Related]  

  • 46. New ABCC8 mutations in relapsing neonatal diabetes and clinical features.
    Vaxillaire M; Dechaume A; Busiah K; Cavé H; Pereira S; Scharfmann R; de Nanclares GP; Castano L; Froguel P; Polak M;
    Diabetes; 2007 Jun; 56(6):1737-41. PubMed ID: 17389331
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels.
    Rainbow RD; James M; Hudman D; Al Johi M; Singh H; Watson PJ; Ashmole I; Davies NW; Lodwick D; Norman RI
    Biochem J; 2004 Apr; 379(Pt 1):173-81. PubMed ID: 14672537
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Glibenclamide binding to sulphonylurea receptor subtypes: dependence on adenine nucleotides.
    Hambrock A; Löffler-Walz C; Quast U
    Br J Pharmacol; 2002 Aug; 136(7):995-1004. PubMed ID: 12145099
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels.
    Ammälä C; Moorhouse A; Gribble F; Ashfield R; Proks P; Smith PA; Sakura H; Coles B; Ashcroft SJ; Ashcroft FM
    Nature; 1996 Feb; 379(6565):545-8. PubMed ID: 8596634
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.
    Fatehi M; Raja M; Carter C; Soliman D; Holt A; Light PE
    Diabetes; 2012 Jan; 61(1):241-9. PubMed ID: 22187380
    [TBL] [Abstract][Full Text] [Related]  

  • 51. A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated.
    Männikkö R; Stansfeld PJ; Ashcroft AS; Hattersley AT; Sansom MS; Ellard S; Ashcroft FM
    J Physiol; 2011 Jul; 589(Pt 13):3071-83. PubMed ID: 21540348
    [TBL] [Abstract][Full Text] [Related]  

  • 52. A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 beta-cells.
    Tarasov AI; Welters HJ; Senkel S; Ryffel GU; Hattersley AT; Morgan NG; Ashcroft FM
    Diabetes; 2006 Nov; 55(11):3075-82. PubMed ID: 17065345
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences.
    Flechtner I; de Lonlay P; Polak M
    Diabetes Metab; 2006 Dec; 32(6):569-80. PubMed ID: 17296510
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function.
    Marthinet E; Bloc A; Oka Y; Tanizawa Y; Wehrle-Haller B; Bancila V; Dubuis JM; Philippe J; Schwitzgebel VM
    J Clin Endocrinol Metab; 2005 Sep; 90(9):5401-6. PubMed ID: 15998776
    [TBL] [Abstract][Full Text] [Related]  

  • 55. A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome.
    Proks P; Girard C; Haider S; Gloyn AL; Hattersley AT; Sansom MS; Ashcroft FM
    EMBO Rep; 2005 May; 6(5):470-5. PubMed ID: 15864298
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors.
    Schwanstecher M; Sieverding C; Dörschner H; Gross I; Aguilar-Bryan L; Schwanstecher C; Bryan J
    EMBO J; 1998 Oct; 17(19):5529-35. PubMed ID: 9755153
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Permanent neonatal diabetes due to activating mutations in ABCC8 and KCNJ11.
    Edghill EL; Flanagan SE; Ellard S
    Rev Endocr Metab Disord; 2010 Sep; 11(3):193-8. PubMed ID: 20922570
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.
    Gloyn AL; Pearson ER; Antcliff JF; Proks P; Bruining GJ; Slingerland AS; Howard N; Srinivasan S; Silva JM; Molnes J; Edghill EL; Frayling TM; Temple IK; Mackay D; Shield JP; Sumnik Z; van Rhijn A; Wales JK; Clark P; Gorman S; Aisenberg J; Ellard S; Njølstad PR; Ashcroft FM; Hattersley AT
    N Engl J Med; 2004 Apr; 350(18):1838-49. PubMed ID: 15115830
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.
    Brochiero E; Wallendorf B; Gagnon D; Laprade R; Lapointe JY
    Am J Physiol Renal Physiol; 2002 Feb; 282(2):F289-300. PubMed ID: 11788443
    [TBL] [Abstract][Full Text] [Related]  

  • 60. A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.
    de Wet H; Shimomura K; Aittoniemi J; Ahmad N; Lafond M; Sansom MS; Ashcroft FM
    J Physiol; 2012 Oct; 590(20):5025-36. PubMed ID: 22802590
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.