255 related articles for article (PubMed ID: 16087684)
1. Rad50 depletion impacts upon ATR-dependent DNA damage responses.
Zhong H; Bryson A; Eckersdorff M; Ferguson DO
Hum Mol Genet; 2005 Sep; 14(18):2685-93. PubMed ID: 16087684
[TBL] [Abstract][Full Text] [Related]
2. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
3. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.
Olson E; Nievera CJ; Lee AY; Chen L; Wu X
J Biol Chem; 2007 Aug; 282(31):22939-52. PubMed ID: 17526493
[TBL] [Abstract][Full Text] [Related]
4. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
5. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
Taylor AM; Groom A; Byrd PJ
DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
[TBL] [Abstract][Full Text] [Related]
6. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
Duursma AM; Driscoll R; Elias JE; Cimprich KA
Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
[TBL] [Abstract][Full Text] [Related]
7. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
[TBL] [Abstract][Full Text] [Related]
8. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
[TBL] [Abstract][Full Text] [Related]
9. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
10. ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.
Gatei M; Jakob B; Chen P; Kijas AW; Becherel OJ; Gueven N; Birrell G; Lee JH; Paull TT; Lerenthal Y; Fazry S; Taucher-Scholz G; Kalb R; Schindler D; Waltes R; Dörk T; Lavin MF
J Biol Chem; 2011 Sep; 286(36):31542-56. PubMed ID: 21757780
[TBL] [Abstract][Full Text] [Related]
11. Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.
Carson CT; Orazio NI; Lee DV; Suh J; Bekker-Jensen S; Araujo FD; Lakdawala SS; Lilley CE; Bartek J; Lukas J; Weitzman MD
EMBO J; 2009 Mar; 28(6):652-62. PubMed ID: 19197236
[TBL] [Abstract][Full Text] [Related]
12. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
Paull TT; Lee JH
Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
[TBL] [Abstract][Full Text] [Related]
13. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
14. Distinct roles of the ATR kinase and the Mre11-Rad50-Nbs1 complex in the maintenance of chromosomal stability in Arabidopsis.
Amiard S; Charbonnel C; Allain E; Depeiges A; White CI; Gallego ME
Plant Cell; 2010 Sep; 22(9):3020-33. PubMed ID: 20876831
[TBL] [Abstract][Full Text] [Related]
15. Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.
Horton JK; Stefanick DF; Zeng JY; Carrozza MJ; Wilson SH
DNA Repair (Amst); 2011 Feb; 10(2):225-34. PubMed ID: 21130714
[TBL] [Abstract][Full Text] [Related]
16. DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
Zhou Y; Paull TT
J Biol Chem; 2013 Dec; 288(52):37112-25. PubMed ID: 24220101
[TBL] [Abstract][Full Text] [Related]
17. Multiple roles for MRE11 at uncapped telomeres.
Deng Y; Guo X; Ferguson DO; Chang S
Nature; 2009 Aug; 460(7257):914-8. PubMed ID: 19633651
[TBL] [Abstract][Full Text] [Related]
18. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
Cerosaletti K; Concannon P
J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
[TBL] [Abstract][Full Text] [Related]
19. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
Lee JH; Paull TT
Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
[TBL] [Abstract][Full Text] [Related]
20. Purification and biochemical characterization of ataxia-telangiectasia mutated and Mre11/Rad50/Nbs1.
Lee JH; Paull TT
Methods Enzymol; 2006; 408():529-39. PubMed ID: 16793391
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
