These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 1608950)

  • 1. Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.
    Chen RH; Maher VM; Brouwer J; van de Putte P; McCormick JJ
    Proc Natl Acad Sci U S A; 1992 Jun; 89(12):5413-7. PubMed ID: 1608950
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra.
    Wei D; Maher VM; McCormick JJ
    Proc Natl Acad Sci U S A; 1995 Mar; 92(6):2204-8. PubMed ID: 7892248
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene.
    Chen RH; Maher VM; McCormick JJ
    Proc Natl Acad Sci U S A; 1990 Nov; 87(21):8680-4. PubMed ID: 2122466
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Relationship between adduct formation, rates of excision repair and the cytotoxic and mutagenic effects of structurally-related polycyclic aromatic carcinogens.
    McGregor WG; Wei D; Chen RH; Maher VM; McCormick JJ
    Mutat Res; 1997 May; 376(1-2):143-52. PubMed ID: 9202750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of a cell cycle-dependent strand bias for mutations induced in the HPRT gene by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in excision repair-deficient human cells.
    Chen RH; Maher VM; McCormick JJ
    Cancer Res; 1991 May; 51(10):2587-92. PubMed ID: 1902394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of nuclear environment on the distribution of benzo[a]pyrene diol epoxide-induced adducts in the HPRT gene of human fibroblasts.
    Wei D; Maher VM; McCormick JJ
    Carcinogenesis; 1996 Dec; 17(12):2695-701. PubMed ID: 9006108
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differences in the rate of DNA adduct removal and the efficiency of mutagenesis for two benzo[a]pyrene diol epoxides in CHO cells.
    MacLeod MC; Daylong A; Adair G; Humphrey RM
    Mutat Res; 1991 Dec; 261(4):267-79. PubMed ID: 1722282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells.
    Schiltz M; Cui XX; Lu YP; Yagi H; Jerina DM; Zdzienicka MZ; Chang RL; Conney AH; Wei SJ
    Carcinogenesis; 1999 Dec; 20(12):2279-86. PubMed ID: 10590220
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.
    Wei SJ; Chang RL; Hennig E; Cui XX; Merkler KA; Wong CQ; Yagi H; Jerina DM; Conney AH
    Carcinogenesis; 1994 Aug; 15(8):1729-35. PubMed ID: 8055656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of correlation between degree of interference with transcription and rate of strand specific repair in the HPRT gene of diploid human fibroblasts.
    McGregor WG; Mah MC; Chen RW; Maher VM; McCormick JJ
    J Biol Chem; 1995 Nov; 270(45):27222-7. PubMed ID: 7592980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
    Denissenko MF; Pao A; Pfeifer GP; Tang M
    Oncogene; 1998 Mar; 16(10):1241-7. PubMed ID: 9546425
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.
    Quan T; Reiners JJ; Culp SJ; Richter P; States JC
    Mol Carcinog; 1995 Feb; 12(2):91-102. PubMed ID: 7662121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes.
    Andersson B; Fält S; Lambert B
    Mutat Res; 1992 Sep; 269(1):129-40. PubMed ID: 1381465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA; Zhu Q; El-Mahdy M; Venkatachalam S; Wani AA
    Cancer Res; 2000 Apr; 60(8):2273-80. PubMed ID: 10786695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells.
    Wei SJ; Chang RL; Bhachech N; Cui XX; Merkler KA; Wong CQ; Hennig E; Yagi H; Jerina DM; Conney AH
    Cancer Res; 1993 Jul; 53(14):3294-301. PubMed ID: 8324741
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Site-specific excision repair of 1-nitrosopyrene-induced DNA adducts at the nucleotide level in the HPRT gene of human fibroblasts: effect of adduct conformation on the pattern of site-specific repair.
    Wei D; Maher VM; McCormick JJ
    Mol Cell Biol; 1996 Jul; 16(7):3714-9. PubMed ID: 8668188
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide.
    Lagerqvist A; Håkansson D; Prochazka G; Lundin C; Dreij K; Segerbäck D; Jernström B; Törnqvist M; Seidel A; Erixon K; Jenssen D
    DNA Repair (Amst); 2008 Aug; 7(8):1202-12. PubMed ID: 18479980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
    Zhan DJ; Heflich RH; Fu PP
    Environ Mol Mutagen; 1996; 27(1):19-29. PubMed ID: 8625944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low absolute mutagenic efficiency but high cytotoxicity of a non-bay region diol epoxide derived from benzo[a]pyrene.
    MacLeod MC; Adair G; Daylong A; Lew L; Humphrey RM
    Mutat Res; 1991 Dec; 261(4):281-93. PubMed ID: 1722283
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential efficiency of mutagenesis at three genetic loci in CHO cells by a benzo[a]pyrene diol epoxide.
    MacLeod MC; Adair G; Humphrey RM
    Mutat Res; 1988 May; 199(1):243-54. PubMed ID: 3129654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.