BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

805 related articles for article (PubMed ID: 16093365)

  • 1. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Taub ME; Podila L; Ely D; Almeida I
    Drug Metab Dispos; 2005 Nov; 33(11):1679-87. PubMed ID: 16093365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay.
    Döppenschmitt S; Langguth P; Regårdh CG; Andersson TB; Hilgendorf C; Spahn-Langguth H
    J Pharmacol Exp Ther; 1999 Jan; 288(1):348-57. PubMed ID: 9862789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
    Tang F; Horie K; Borchardt RT
    Pharm Res; 2002 Jun; 19(6):765-72. PubMed ID: 12134945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin.
    Barthomeuf C; Grassi J; Demeule M; Fournier C; Boivin D; Béliveau R
    Cancer Chemother Pharmacol; 2005 Aug; 56(2):173-81. PubMed ID: 15824923
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport.
    Barthomeuf C; Demeule M; Grassi J; Saidkhodjaev A; Beliveau R
    Planta Med; 2006 Jun; 72(7):634-9. PubMed ID: 16739070
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
    Acharya P; O'Connor MP; Polli JW; Ayrton A; Ellens H; Bentz J
    Drug Metab Dispos; 2008 Feb; 36(2):452-60. PubMed ID: 17967933
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Verapamil metabolites: potential P-glycoprotein-mediated multidrug resistance reversal agents.
    Woodland C; Koren G; Wainer IW; Batist G; Ito S
    Can J Physiol Pharmacol; 2003 Aug; 81(8):800-5. PubMed ID: 12897809
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.
    Lee CG; Gottesman MM; Cardarelli CO; Ramachandra M; Jeang KT; Ambudkar SV; Pastan I; Dey S
    Biochemistry; 1998 Mar; 37(11):3594-601. PubMed ID: 9530286
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caco-2 cell methodology and inhibition of the P-glycoprotein transport of digoxin by Aloe vera juice.
    Djuv A; Nilsen OG
    Phytother Res; 2008 Dec; 22(12):1623-8. PubMed ID: 19003953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stable suppression of MDR1 gene expression and function by RNAi in Caco-2 cells.
    Celius T; Garberg P; Lundgren B
    Biochem Biophys Res Commun; 2004 Nov; 324(1):365-71. PubMed ID: 15465028
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.
    Lumen AA; Li L; Li J; Ahmed Z; Meng Z; Owen A; Ellens H; Hidalgo IJ; Bentz J
    PLoS One; 2013; 8(8):e69394. PubMed ID: 23976943
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bidirectional transport of rhodamine 123 and Hoechst 33342, fluorescence probes of the binding sites on P-glycoprotein, across MDCK-MDR1 cell monolayers.
    Tang F; Ouyang H; Yang JZ; Borchardt RT
    J Pharm Sci; 2004 May; 93(5):1185-94. PubMed ID: 15067695
    [TBL] [Abstract][Full Text] [Related]  

  • 13. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.
    Acharya P; Tran TT; Polli JW; Ayrton A; Ellens H; Bentz J
    Biochemistry; 2006 Dec; 45(51):15505-19. PubMed ID: 17176072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transport of dietary phenethyl isothiocyanate is mediated by multidrug resistance protein 2 but not P-glycoprotein.
    Ji Y; Morris ME
    Biochem Pharmacol; 2005 Aug; 70(4):640-7. PubMed ID: 16002050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of the coumarinic acid-based cyclic prodrug of the opioid peptide DADLE.
    Tang F; Borchardt RT
    Pharm Res; 2002 Jun; 19(6):787-93. PubMed ID: 12134948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evasion of P-gp mediated cellular efflux and permeability enhancement of HIV-protease inhibitor saquinavir by prodrug modification.
    Jain R; Agarwal S; Majumdar S; Zhu X; Pal D; Mitra AK
    Int J Pharm; 2005 Oct; 303(1-2):8-19. PubMed ID: 16137847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of an acyloxyalkoxy-based cyclic prodrug of the opioid peptide DADLE.
    Tang F; Borchardt RT
    Pharm Res; 2002 Jun; 19(6):780-6. PubMed ID: 12134947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.
    Jutabha P; Wempe MF; Anzai N; Otomo J; Kadota T; Endou H
    Pharmacol Res; 2010 Jan; 61(1):76-84. PubMed ID: 19631272
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of continuous exposure to digoxin on MDR1 function and expression in Caco-2 cells.
    Takara K; Tsujimoto M; Ohnishi N; Yokoyama T
    J Pharm Pharmacol; 2003 May; 55(5):675-81. PubMed ID: 12831511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
    Tanigawara Y; Okamura N; Hirai M; Yasuhara M; Ueda K; Kioka N; Komano T; Hori R
    J Pharmacol Exp Ther; 1992 Nov; 263(2):840-5. PubMed ID: 1359120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.