BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 16103115)

  • 1. A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
    Holm MM; Naur P; Vestergaard B; Geballe MT; Gajhede M; Kastrup JS; Traynelis SF; Egebjerg J
    J Biol Chem; 2005 Oct; 280(42):35469-76. PubMed ID: 16103115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.
    Holm MM; Lunn ML; Traynelis SF; Kastrup JS; Egebjerg J
    Proc Natl Acad Sci U S A; 2005 Aug; 102(34):12053-8. PubMed ID: 16099829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.
    Frandsen A; Pickering DS; Vestergaard B; Kasper C; Nielsen BB; Greenwood JR; Campiani G; Fattorusso C; Gajhede M; Schousboe A; Kastrup JS
    Mol Pharmacol; 2005 Mar; 67(3):703-13. PubMed ID: 15591246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.
    Zhang Y; Nayeem N; Nanao MH; Green T
    J Neurosci; 2006 Sep; 26(39):10033-42. PubMed ID: 17005866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.
    Hogner A; Kastrup JS; Jin R; Liljefors T; Mayer ML; Egebjerg J; Larsen IK; Gouaux E
    J Mol Biol; 2002 Sep; 322(1):93-109. PubMed ID: 12215417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stargazin interaction with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors is critically dependent on the amino acid at the narrow constriction of the ion channel.
    Körber C; Werner M; Hoffmann J; Sager C; Tietze M; Schmid SM; Kott S; Hollmann M
    J Biol Chem; 2007 Jun; 282(26):18758-66. PubMed ID: 17483093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
    Mayer ML; Ghosal A; Dolman NP; Jane DE
    J Neurosci; 2006 Mar; 26(11):2852-61. PubMed ID: 16540562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate.
    Jin R; Horning M; Mayer ML; Gouaux E
    Biochemistry; 2002 Dec; 41(52):15635-43. PubMed ID: 12501192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of kinetic properties of GluR2 AMPA receptor channels by alternative splicing.
    Koike M; Tsukada S; Tsuzuki K; Kijima H; Ozawa S
    J Neurosci; 2000 Mar; 20(6):2166-74. PubMed ID: 10704491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
    Armstrong N; Mayer M; Gouaux E
    Proc Natl Acad Sci U S A; 2003 May; 100(10):5736-41. PubMed ID: 12730367
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional consequences of natural substitutions in the GluR6 kainate receptor subunit ligand-binding site.
    Kistler T; Fleck MW
    Channels (Austin); 2007; 1(6):417-28. PubMed ID: 18690046
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2alpha,3beta,4beta)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study.
    Pentikäinen OT; Settimo L; Keinänen K; Johnson MS
    Biochem Pharmacol; 2003 Dec; 66(12):2413-25. PubMed ID: 14637199
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
    Jin R; Gouaux E
    Biochemistry; 2003 May; 42(18):5201-13. PubMed ID: 12731861
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes.
    Wahl P; Madsen U; Banke T; Krogsgaard-Larsen P; Schousboe A
    Eur J Pharmacol; 1996 Jul; 308(2):211-8. PubMed ID: 8840134
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations to the kainate receptor subunit GluR6 binding pocket that selectively affect domoate binding.
    Zhang Y; Nayeem N; Green T
    Mol Pharmacol; 2008 Oct; 74(4):1163-9. PubMed ID: 18664604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
    Armstrong N; Gouaux E
    Neuron; 2000 Oct; 28(1):165-81. PubMed ID: 11086992
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.
    Johnson WD; Parandaman V; Onaivi ES; Taylor RE; Akinshola BE
    Brain Res; 2008 Jul; 1222():18-30. PubMed ID: 18585685
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain.
    Yelshansky MV; Sobolevsky AI; Jatzke C; Wollmuth LP
    J Neurosci; 2004 May; 24(20):4728-36. PubMed ID: 15152033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptors.
    Chen PE; Johnston AR; Mok MH; Schoepfer R; Wyllie DJ
    J Physiol; 2004 Jul; 558(Pt 1):45-58. PubMed ID: 15107472
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A conserved mechanism for gating in an ionotropic glutamate receptor.
    Moore BS; Mirshahi UL; Ebersole TL; Mirshahi T
    J Biol Chem; 2013 Jun; 288(26):18842-52. PubMed ID: 23671286
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.