These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 16114043)

  • 1. Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
    Djojosubroto MW; Chin AC; Go N; Schaetzlein S; Manns MP; Gryaznov S; Harley CB; Rudolph KL
    Hepatology; 2005 Nov; 42(5):1127-36. PubMed ID: 16114043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.
    Herbert BS; Gellert GC; Hochreiter A; Pongracz K; Wright WE; Zielinska D; Chin AC; Harley CB; Shay JW; Gryaznov SM
    Oncogene; 2005 Aug; 24(33):5262-8. PubMed ID: 15940257
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.
    Hochreiter AE; Xiao H; Goldblatt EM; Gryaznov SM; Miller KD; Badve S; Sledge GW; Herbert BS
    Clin Cancer Res; 2006 May; 12(10):3184-92. PubMed ID: 16707619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.
    Gomez-Millan J; Goldblatt EM; Gryaznov SM; Mendonca MS; Herbert BS
    Int J Radiat Oncol Biol Phys; 2007 Mar; 67(3):897-905. PubMed ID: 17175117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer.
    Gellert GC; Dikmen ZG; Wright WE; Gryaznov S; Shay JW
    Breast Cancer Res Treat; 2006 Mar; 96(1):73-81. PubMed ID: 16319992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.
    Dikmen ZG; Gellert GC; Jackson S; Gryaznov S; Tressler R; Dogan P; Wright WE; Shay JW
    Cancer Res; 2005 Sep; 65(17):7866-73. PubMed ID: 16140956
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomerase targeted oligonucleotide thio-phosphoramidates in T24-luc bladder cancer cells.
    Dikmen ZG; Wright WE; Shay JW; Gryaznov SM
    J Cell Biochem; 2008 May; 104(2):444-52. PubMed ID: 18044713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
    Asai A; Oshima Y; Yamamoto Y; Uochi TA; Kusaka H; Akinaga S; Yamashita Y; Pongracz K; Pruzan R; Wunder E; Piatyszek M; Li S; Chin AC; Harley CB; Gryaznov S
    Cancer Res; 2003 Jul; 63(14):3931-9. PubMed ID: 12873987
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oligonucleotide conjugate GRN163L targeting human telomerase as potential anticancer and antimetastatic agent.
    Gryaznov SM; Jackson S; Dikmen G; Harley C; Herbert BS; Wright WE; Shay JW
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1577-9. PubMed ID: 18066830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.
    Chen H; Takahashi S; Imamura M; Okutani E; Zhang ZG; Chayama K; Chen BA
    Chin Med J (Engl); 2007 May; 120(10):898-904. PubMed ID: 17543180
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oligonucleotide N3' --> P5' thio-phosphoramidate telomerase template antagonists as potential anticancer agents.
    Gryaznov S; Asai A; Oshima Y; Yamamoto Y; Pongracz K; Pruzan R; Wunder E; Piatyszek M; Li S; Chin A; Harley C; Akinaga S; Yamashita Y
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):577-81. PubMed ID: 14565232
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells.
    Lin CP; Liu JD; Chow JM; Liu CR; Liu HE
    Anticancer Drugs; 2007 Feb; 18(2):161-70. PubMed ID: 17159602
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
    Ozawa T; Gryaznov SM; Hu LJ; Pongracz K; Santos RA; Bollen AW; Lamborn KR; Deen DF
    Neuro Oncol; 2004 Jul; 6(3):218-26. PubMed ID: 15279714
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.
    Herbert BS; Pongracz K; Shay JW; Gryaznov SM
    Oncogene; 2002 Jan; 21(4):638-42. PubMed ID: 11850790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects.
    Kelland LR
    Eur J Cancer; 2005 May; 41(7):971-9. PubMed ID: 15862745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
    Jackson SR; Zhu CH; Paulson V; Watkins L; Dikmen ZG; Gryaznov SM; Wright WE; Shay JW
    Cancer Res; 2007 Feb; 67(3):1121-9. PubMed ID: 17283146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
    Mi JX; Wang GF; Wang HB; Sun XQ; Ni XY; Zhang XW; Tang JM; Yang DJ
    Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Doxorubicin modulates telomerase activity in Ewing's sarcoma in vitro and in vivo.
    Lanvers-Kaminsky C; Winter B; Koling S; Frodermann B; Braun Y; Schaefer KL; Diallo R; Koenemann S; Wai D; Willich N; Poremba C; Schuck A
    Oncol Rep; 2005 Sep; 14(3):751-8. PubMed ID: 16077987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells.
    Zhang RG; Zhang RP; Wang XW; Xie H
    Cell Res; 2002 Mar; 12(1):55-62. PubMed ID: 11942411
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Telomeres and telomerase: a dual role in hepatocarcinogenesis.
    Satyanarayana A; Manns MP; Rudolph KL
    Hepatology; 2004 Aug; 40(2):276-83. PubMed ID: 15368430
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.