BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

491 related articles for article (PubMed ID: 16118324)

  • 1. BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.
    Erlacher M; Michalak EM; Kelly PN; Labi V; Niederegger H; Coultas L; Adams JM; Strasser A; Villunger A
    Blood; 2005 Dec; 106(13):4131-8. PubMed ID: 16118324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells.
    Bauer A; Villunger A; Labi V; Fischer SF; Strasser A; Wagner H; Schmid RM; Häcker G
    Proc Natl Acad Sci U S A; 2006 Jul; 103(29):10979-84. PubMed ID: 16832056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.
    Wali JA; Rondas D; McKenzie MD; Zhao Y; Elkerbout L; Fynch S; Gurzov EN; Akira S; Mathieu C; Kay TW; Overbergh L; Strasser A; Thomas HE
    Cell Death Dis; 2014 Mar; 5(3):e1124. PubMed ID: 24625983
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetically defining the mechanism of Puma- and Bim-induced apoptosis.
    Garrison SP; Phillips DC; Jeffers JR; Chipuk JE; Parsons MJ; Rehg JE; Opferman JT; Green DR; Zambetti GP
    Cell Death Differ; 2012 Apr; 19(4):642-9. PubMed ID: 22015606
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction.
    Erlacher M; Labi V; Manzl C; Böck G; Tzankov A; Häcker G; Michalak E; Strasser A; Villunger A
    J Exp Med; 2006 Dec; 203(13):2939-51. PubMed ID: 17178918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
    Ren D; Tu HC; Kim H; Wang GX; Bean GR; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Science; 2010 Dec; 330(6009):1390-3. PubMed ID: 21127253
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo.
    Tsuchiya T; Bonner HP; Engel T; Woods I; Matsushima S; Ward MW; Taki W; Henshall DC; Concannon CG; Prehn JH
    Eur J Neurosci; 2011 Feb; 33(3):401-8. PubMed ID: 21198986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis.
    Ghosh AP; Walls KC; Klocke BJ; Toms R; Strasser A; Roth KA
    J Neuropathol Exp Neurol; 2009 Jul; 68(7):747-56. PubMed ID: 19535997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development.
    Kelly PN; White MJ; Goschnick MW; Fairfax KA; Tarlinton DM; Kinkel SA; Bouillet P; Adams JM; Kile BT; Strasser A
    Cell Death Differ; 2010 Oct; 17(10):1655-64. PubMed ID: 20431598
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.
    Jabbour AM; Heraud JE; Daunt CP; Kaufmann T; Sandow J; O'Reilly LA; Callus BA; Lopez A; Strasser A; Vaux DL; Ekert PG
    Cell Death Differ; 2009 Apr; 16(4):555-63. PubMed ID: 19079139
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.
    Huntington ND; Labi V; Cumano A; Vieira P; Strasser A; Villunger A; Di Santo JP; Alves NL
    Int Immunol; 2009 Jun; 21(6):715-25. PubMed ID: 19454543
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma.
    Ekert PG; Jabbour AM; Manoharan A; Heraud JE; Yu J; Pakusch M; Michalak EM; Kelly PN; Callus B; Kiefer T; Verhagen A; Silke J; Strasser A; Borner C; Vaux DL
    Blood; 2006 Sep; 108(5):1461-8. PubMed ID: 16705087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress.
    Ghosh AP; Klocke BJ; Ballestas ME; Roth KA
    PLoS One; 2012; 7(6):e39586. PubMed ID: 22761832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.
    Villunger A; Michalak EM; Coultas L; Müllauer F; Böck G; Ausserlechner MJ; Adams JM; Strasser A
    Science; 2003 Nov; 302(5647):1036-8. PubMed ID: 14500851
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus.
    Bunk EC; König HG; Bernas T; Engel T; Henshall DC; Kirby BP; Prehn JH
    Cell Death Dis; 2010; 1(1):e15. PubMed ID: 21364616
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute.
    Michalak EM; Villunger A; Adams JM; Strasser A
    Cell Death Differ; 2008 Jun; 15(6):1019-29. PubMed ID: 18259198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition.
    Tuffy LP; Concannon CG; D'Orsi B; King MA; Woods I; Huber HJ; Ward MW; Prehn JH
    Mol Cell Biol; 2010 Dec; 30(23):5484-501. PubMed ID: 20921277
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
    Valente LJ; Gray DH; Michalak EM; Pinon-Hofbauer J; Egle A; Scott CL; Janic A; Strasser A
    Cell Rep; 2013 May; 3(5):1339-45. PubMed ID: 23665218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The BH3-only protein Puma plays an essential role in p53-mediated apoptosis of chronic lymphocytic leukemia cells.
    Zhu HJ; Liu L; Fan L; Zhang LN; Fang C; Zou ZJ; Li JY; Xu W
    Leuk Lymphoma; 2013 Dec; 54(12):2712-9. PubMed ID: 23517560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.