These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

380 related articles for article (PubMed ID: 16120446)

  • 1. On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
    Kulik V; Hartmann E; Weyand M; Frey M; Gierl A; Niks D; Dunn MF; Schlichting I
    J Mol Biol; 2005 Sep; 352(3):608-20. PubMed ID: 16120446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cooperative fluctuations and subunit communication in tryptophan synthase.
    Bahar I; Jernigan RL
    Biochemistry; 1999 Mar; 38(12):3478-90. PubMed ID: 10090734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium.
    Raboni S; Mozzarelli A; Cook PF
    Biochemistry; 2007 Nov; 46(45):13223-34. PubMed ID: 17927213
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
    Rhee S; Parris KD; Hyde CC; Ahmed SA; Miles EW; Davies DR
    Biochemistry; 1997 Jun; 36(25):7664-80. PubMed ID: 9201907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loop closure and intersubunit communication in tryptophan synthase.
    Schneider TR; Gerhardt E; Lee M; Liang PH; Anderson KS; Schlichting I
    Biochemistry; 1998 Apr; 37(16):5394-406. PubMed ID: 9548921
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Affinities of phosphorylated substrates for the E. coli tryptophan synthase alpha-subunit: roles of Ser-235 and helix-8' dipole.
    Sarker KD; Hardman JK
    Proteins; 1995 Feb; 21(2):130-9. PubMed ID: 7777488
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tryptophan synthase: the workings of a channeling nanomachine.
    Dunn MF; Niks D; Ngo H; Barends TR; Schlichting I
    Trends Biochem Sci; 2008 Jun; 33(6):254-64. PubMed ID: 18486479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tryptophan synthase, an allosteric molecular factory.
    Barends TR; Dunn MF; Schlichting I
    Curr Opin Chem Biol; 2008 Oct; 12(5):593-600. PubMed ID: 18675375
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone.
    Nishio K; Morimoto Y; Ishizuka M; Ogasahara K; Tsukihara T; Yutani K
    Biochemistry; 2005 Feb; 44(4):1184-92. PubMed ID: 15667212
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterisation of the tryptophan synthase alpha subunit in maize.
    Kriechbaumer V; Weigang L; Fiesselmann A; Letzel T; Frey M; Gierl A; Glawischnig E
    BMC Plant Biol; 2008 Apr; 8():44. PubMed ID: 18430213
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole.
    Cash MT; Miles EW; Phillips RS
    Arch Biochem Biophys; 2004 Dec; 432(2):233-43. PubMed ID: 15542062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Large conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate binding.
    Nishio K; Ogasahara K; Morimoto Y; Tsukihara T; Lee SJ; Yutani K
    FEBS J; 2010 May; 277(9):2157-70. PubMed ID: 20370823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the functional role of a flexible loop in the alpha-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis.
    Brzović PS; Hyde CC; Miles EW; Dunn MF
    Biochemistry; 1993 Oct; 32(39):10404-13. PubMed ID: 8399184
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational Changes in the tryptophan synthase from a hyperthermophile upon alpha2beta2 complex formation: crystal structure of the complex.
    Lee SJ; Ogasahara K; Ma J; Nishio K; Ishida M; Yamagata Y; Tsukihara T; Yutani K
    Biochemistry; 2005 Aug; 44(34):11417-27. PubMed ID: 16114878
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serine modulates substrate channeling in tryptophan synthase. A novel intersubunit triggering mechanism.
    Anderson KS; Miles EW; Johnson KA
    J Biol Chem; 1991 May; 266(13):8020-33. PubMed ID: 1902468
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase.
    Schlichting I; Yang XJ; Miles EW; Kim AY; Anderson KS
    J Biol Chem; 1994 Oct; 269(43):26591-3. PubMed ID: 7929385
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arabidopsis indole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis.
    Zhang R; Wang B; Ouyang J; Li J; Wang Y
    J Integr Plant Biol; 2008 Sep; 50(9):1070-7. PubMed ID: 18844775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex.
    Pan P; Dunn MF
    Biochemistry; 1996 Apr; 35(15):5002-13. PubMed ID: 8664293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structures of wild-type and P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli.
    Jeong MS; Jeong JK; Lim WK; Jang SB
    Biochem Biophys Res Commun; 2004 Oct; 323(4):1257-64. PubMed ID: 15451433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
    Ngo H; Harris R; Kimmich N; Casino P; Niks D; Blumenstein L; Barends TR; Kulik V; Weyand M; Schlichting I; Dunn MF
    Biochemistry; 2007 Jul; 46(26):7713-27. PubMed ID: 17559195
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.