289 related articles for article (PubMed ID: 16124035)
1. High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.
Kim MJ; Kim H; Cha IJ; Park JS; Shon JH; Liu KH; Shin JG
Rapid Commun Mass Spectrom; 2005; 19(18):2651-8. PubMed ID: 16124035
[TBL] [Abstract][Full Text] [Related]
2. Validated assays for human cytochrome P450 activities.
Walsky RL; Obach RS
Drug Metab Dispos; 2004 Jun; 32(6):647-60. PubMed ID: 15155557
[TBL] [Abstract][Full Text] [Related]
3. A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.
Dierks EA; Stams KR; Lim HK; Cornelius G; Zhang H; Ball SE
Drug Metab Dispos; 2001 Jan; 29(1):23-9. PubMed ID: 11124225
[TBL] [Abstract][Full Text] [Related]
4. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
Lee B; Ji HK; Lee T; Liu KH
Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
[TBL] [Abstract][Full Text] [Related]
5. Screening of ten cytochrome P450 enzyme activities with 12 probe substrates in human liver microsomes using cocktail incubation and liquid chromatography-tandem mass spectrometry.
Kim HJ; Lee H; Ji HK; Lee T; Liu KH
Biopharm Drug Dispos; 2019 Apr; 40(3-4):101-111. PubMed ID: 30730576
[TBL] [Abstract][Full Text] [Related]
6. A comprehensive assay for nine major cytochrome P450 enzymes activities with 16 probe reactions on human liver microsomes by a single LC/MS/MS run to support reliable in vitro inhibitory drug-drug interaction evaluation.
Peng Y; Wu H; Zhang X; Zhang F; Qi H; Zhong Y; Wang Y; Sang H; Wang G; Sun J
Xenobiotica; 2015; 45(11):961-77. PubMed ID: 26007223
[TBL] [Abstract][Full Text] [Related]
7. Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.
Lee KS; Kim SK
J Appl Toxicol; 2013 Feb; 33(2):100-8. PubMed ID: 21915887
[TBL] [Abstract][Full Text] [Related]
8. Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.
Zhang W; Han F; Guo P; Zhao H; Lin ZJ; Huang MQ; Bertelsen K; Weng N
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(15-16):1169-77. PubMed ID: 20378422
[TBL] [Abstract][Full Text] [Related]
9. In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies.
Tolonen A; Petsalo A; Turpeinen M; Uusitalo J; Pelkonen O
J Mass Spectrom; 2007 Jul; 42(7):960-6. PubMed ID: 17565714
[TBL] [Abstract][Full Text] [Related]
10. [Simultaneous determination of the inhibitory potency of compounds on the activity of five cytochrome P-450 enzymes using a cocktail probe substrates method].
Gao ZW; Shi XJ; Yu C; Li SJ; Zhong MK
Yao Xue Xue Bao; 2007 Jun; 42(6):589-94. PubMed ID: 17702393
[TBL] [Abstract][Full Text] [Related]
11. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
[TBL] [Abstract][Full Text] [Related]
12. High-throughput cytochrome p450 inhibition assays by ultrafast gradient liquid chromatography with tandem mass spectrometry using monolithic columns.
Peng SX; Barbone AG; Ritchie DM
Rapid Commun Mass Spectrom; 2003; 17(6):509-18. PubMed ID: 12621611
[TBL] [Abstract][Full Text] [Related]
13. Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay.
Turpeinen M; Uusitalo J; Jalonen J; Pelkonen O
Eur J Pharm Sci; 2005 Jan; 24(1):123-32. PubMed ID: 15626586
[TBL] [Abstract][Full Text] [Related]
14. Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography-tandem mass spectrometry.
Li X; Chen X; Li Q; Wang L; Zhong D
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jun; 852(1-2):128-37. PubMed ID: 17267297
[TBL] [Abstract][Full Text] [Related]
15. Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.
Perloff ES; Mason AK; Dehal SS; Blanchard AP; Morgan L; Ho T; Dandeneau A; Crocker RM; Chandler CM; Boily N; Crespi CL; Stresser DM
Xenobiotica; 2009 Feb; 39(2):99-112. PubMed ID: 19255936
[TBL] [Abstract][Full Text] [Related]
16. Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery.
Smith D; Sadagopan N; Zientek M; Reddy A; Cohen L
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 May; 850(1-2):455-63. PubMed ID: 17270503
[TBL] [Abstract][Full Text] [Related]
17. Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography-tandem mass spectrometry utilizing sub 2 microm particle size column.
Petsalo A; Turpeinen M; Pelkonen O; Tolonen A
J Chromatogr A; 2008 Dec; 1215(1-2):107-15. PubMed ID: 19019380
[TBL] [Abstract][Full Text] [Related]
18. A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.
Qin CZ; Ren X; Tan ZR; Chen Y; Yin JY; Yu J; Qu J; Zhou HH; Liu ZQ
Biomed Chromatogr; 2014 Feb; 28(2):197-203. PubMed ID: 23946123
[TBL] [Abstract][Full Text] [Related]
19. Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.
Feidt DM; Klein K; Hofmann U; Riedmaier S; Knobeloch D; Thasler WE; Weiss TS; Schwab M; Zanger UM
Drug Metab Dispos; 2010 Sep; 38(9):1589-97. PubMed ID: 20551241
[TBL] [Abstract][Full Text] [Related]
20. An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes - application to establishing CYP2C8 inhibitor selectivity.
Kahma H; Aurinsalo L; Neuvonen M; Katajamäki J; Paludetto MN; Viinamäki J; Launiainen T; Filppula AM; Tornio A; Niemi M; Backman JT
Eur J Pharm Sci; 2021 Jul; 162():105810. PubMed ID: 33753217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
