BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

443 related articles for article (PubMed ID: 16124869)

  • 1. PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.
    Liang SH; Zhang W; McGrath BC; Zhang P; Cavener DR
    Biochem J; 2006 Jan; 393(Pt 1):201-9. PubMed ID: 16124869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. T-cadherin attenuates the PERK branch of the unfolded protein response and protects vascular endothelial cells from endoplasmic reticulum stress-induced apoptosis.
    Kyriakakis E; Philippova M; Joshi MB; Pfaff D; Bochkov V; Afonyushkin T; Erne P; Resink TJ
    Cell Signal; 2010 Sep; 22(9):1308-16. PubMed ID: 20457250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.
    Yan W; Frank CL; Korth MJ; Sopher BL; Novoa I; Ron D; Katze MG
    Proc Natl Acad Sci U S A; 2002 Dec; 99(25):15920-5. PubMed ID: 12446838
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc.
    Yaari-Stark S; Shaked M; Nevo-Caspi Y; Jacob-Hircsh J; Shamir R; Rechavi G; Kloog Y
    Int J Cancer; 2010 May; 126(10):2268-81. PubMed ID: 19998334
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.
    Huang G; Yao J; Zeng W; Mizuno Y; Kamm KE; Stull JT; Harding HP; Ron D; Muallem S
    J Cell Sci; 2006 Jan; 119(Pt 1):153-61. PubMed ID: 16352659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.
    Xue M; Fu F; Ma Y; Zhang X; Li L; Feng L; Liu P
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29769338
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs.
    Bollo M; Paredes RM; Holstein D; Zheleznova N; Camacho P; Lechleiter JD
    PLoS One; 2010 Aug; 5(8):e11925. PubMed ID: 20700529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress.
    Zhu X; Zelmer A; Kapfhammer JP; Wellmann S
    FASEB J; 2016 Feb; 30(2):624-34. PubMed ID: 26472337
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress.
    Kim KM; Pae HO; Zheng M; Park R; Kim YM; Chung HT
    Circ Res; 2007 Oct; 101(9):919-27. PubMed ID: 17823375
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.
    Blohmke CJ; Mayer ML; Tang AC; Hirschfeld AF; Fjell CD; Sze MA; Falsafi R; Wang S; Hsu K; Chilvers MA; Hogg JC; Hancock RE; Turvey SE
    J Immunol; 2012 Dec; 189(11):5467-75. PubMed ID: 23105139
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.
    Gupta S; Giricz Z; Natoni A; Donnelly N; Deegan S; Szegezdi E; Samali A
    FEBS Lett; 2012 Nov; 586(22):4023-30. PubMed ID: 23068609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress.
    Gardner OS; Shiau CW; Chen CS; Graves LM
    J Biol Chem; 2005 Mar; 280(11):10109-18. PubMed ID: 15649892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress.
    Feng YX; Sokol ES; Del Vecchio CA; Sanduja S; Claessen JH; Proia TA; Jin DX; Reinhardt F; Ploegh HL; Wang Q; Gupta PB
    Cancer Discov; 2014 Jun; 4(6):702-15. PubMed ID: 24705811
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish.
    Komoike Y; Matsuoka M
    Aquat Toxicol; 2013 Oct; 142-143():221-9. PubMed ID: 24055755
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins.
    Sanderson TH; Deogracias MP; Nangia KK; Wang J; Krause GS; Kumar R
    Neuroscience; 2010 Sep; 169(3):1307-14. PubMed ID: 20538047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival.
    Hengstermann A; Müller T
    Free Radic Biol Med; 2008 Mar; 44(6):1097-107. PubMed ID: 18206657
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The neuro-steroid, 5-androstene 3β,17α diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2α signaling in malignant glioma cells and transformed fibroblasts.
    Jia W; Loria RM; Park MA; Yacoub A; Dent P; Graf MR
    Int J Biochem Cell Biol; 2010 Dec; 42(12):2019-29. PubMed ID: 20851775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells.
    Vaughn LS; Snee B; Patel RC
    Gene; 2014 Feb; 536(1):90-6. PubMed ID: 24334130
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.
    Moore CE; Omikorede O; Gomez E; Willars GB; Herbert TP
    Mol Endocrinol; 2011 Feb; 25(2):315-26. PubMed ID: 21193559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Coordination of stress, Ca2+, and immunogenic signaling pathways by PERK at the endoplasmic reticulum.
    van Vliet AR; Garg AD; Agostinis P
    Biol Chem; 2016 Jul; 397(7):649-56. PubMed ID: 26872313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.