BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 1612955)

  • 1. Hypobaric hypoxia: a method for testing bioreductive drugs in vivo.
    McAleer JJ; McKeown SR; MacManus MP; Lappin TR; Bridges JM
    Int J Radiat Oncol Biol Phys; 1992; 23(3):551-5. PubMed ID: 1612955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo.
    McKeown SR; Hejmadi MV; McIntyre IA; McAleer JJ; Patterson LH
    Br J Cancer; 1995 Jul; 72(1):76-81. PubMed ID: 7599069
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxic sensitizer and cytotoxin for head and neck cancer.
    Lee DJ; Moini M; Giuliano J; Westra WH
    Ann Acad Med Singap; 1996 May; 25(3):397-404. PubMed ID: 8876907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive agent as radiosensitizer in vitro and in vivo: comparison with tirapazamine.
    Papadopoulou MV; Ji M; Rao MK; Bloomer WD
    Oncol Res; 2001; 12(8):325-33. PubMed ID: 11589303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of oncogenicity for bioreductive drugs.
    Hei TK; Piao CQ; He ZY; Hall EJ
    Int J Radiat Oncol Biol Phys; 1992; 22(4):747-50. PubMed ID: 1544847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bioreductive drugs in cancer therapy.
    Stratford IJ
    BJR Suppl; 1992; 24():128-36. PubMed ID: 1341908
    [No Abstract]   [Full Text] [Related]  

  • 7. Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9.
    Adams GE; Stratford IJ; Edwards HS; Bremner JC; Cole S
    Int J Radiat Oncol Biol Phys; 1992; 22(4):717-20. PubMed ID: 1544844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
    Cole S; Stratford IJ; Adams GE; Fielden EM; Jenkins TC
    Radiat Res; 1990 Oct; 124(1 Suppl):S38-43. PubMed ID: 2236508
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acute lesions in rats caused by 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) or nitromin: a comparison with rates of reduction in microsomal systems from target organs.
    White IN; Cahill A; Davies A; Carthew P
    Arch Toxicol; 1992; 66(2):100-6. PubMed ID: 1605723
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA damage induced in T50/80 tumour cells following exposure to the bioreductive drug Tirapazamine in combination with a single dose of radiation (12Gy).
    Friery OP; Hejmadi MV; McKeown SR
    Biochem Soc Trans; 1997 Feb; 25(1):135S. PubMed ID: 9057033
    [No Abstract]   [Full Text] [Related]  

  • 11. The experimental development of bioreductive drugs and their role in cancer therapy.
    Workman P; Stratford IJ
    Cancer Metastasis Rev; 1993 Jun; 12(2):73-82. PubMed ID: 8375022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bioreductive therapy.
    Chaplin DJ
    Int J Radiat Oncol Biol Phys; 1992; 22(4):685-7. PubMed ID: 1544837
    [No Abstract]   [Full Text] [Related]  

  • 13. Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine.
    Friery OP; Gallagher R; Murray MM; Hughes CM; Galligan ES; McIntyre IA; Patterson LH; Hirst DG; McKeown SR
    Br J Cancer; 2000 Apr; 82(8):1469-73. PubMed ID: 10780528
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive anti-tumor agents: pharmacology and activity in vitro and in vivo.
    Minchinton AI; Lemmon MJ; Tracy M; Pollart DJ; Martinez AP; Tosto LM; Brown JM
    Int J Radiat Oncol Biol Phys; 1992; 22(4):701-5. PubMed ID: 1544841
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells.
    Zeman EM; Brown JM; Lemmon MJ; Hirst VK; Lee WW
    Int J Radiat Oncol Biol Phys; 1986 Jul; 12(7):1239-42. PubMed ID: 3744945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice.
    Lee AE; Wilson WR
    Toxicol Appl Pharmacol; 2000 Feb; 163(1):50-9. PubMed ID: 10662604
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine.
    Beck R; Röper B; Carlsen JM; Huisman MC; Lebschi JA; Andratschke N; Picchio M; Souvatzoglou M; Machulla HJ; Piert M
    J Nucl Med; 2007 Jun; 48(6):973-80. PubMed ID: 17536108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions.
    Cahill A; Jenkins TC; Pickering P; White IN
    Chem Biol Interact; 1995 Mar; 95(1-2):97-107. PubMed ID: 7697757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bioreductive therapies: an overview of drugs and their mechanisms of action.
    Rauth AM; Melo T; Misra V
    Int J Radiat Oncol Biol Phys; 1998 Nov; 42(4):755-62. PubMed ID: 9845091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of radiation and tirapazamine (SR-4233) on three melanoma cell lines.
    Zhang M; Stevens G
    Melanoma Res; 1998 Dec; 8(6):510-5. PubMed ID: 9918413
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.