198 related articles for article (PubMed ID: 16129665)
1. Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis.
Meruvu S; Walther M; Ivanov I; Hammarström S; Fürstenberger G; Krieg P; Reddanna P; Kuhn H
J Biol Chem; 2005 Nov; 280(44):36633-41. PubMed ID: 16129665
[TBL] [Abstract][Full Text] [Related]
2. Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2.
Jisaka M; Kim RB; Boeglin WE; Brash AR
J Biol Chem; 2000 Jan; 275(2):1287-93. PubMed ID: 10625675
[TBL] [Abstract][Full Text] [Related]
3. A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation.
Coffa G; Brash AR
Proc Natl Acad Sci U S A; 2004 Nov; 101(44):15579-84. PubMed ID: 15496467
[TBL] [Abstract][Full Text] [Related]
4. Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis.
Walther M; Ivanov I; Myagkova G; Kuhn H
Chem Biol; 2001 Aug; 8(8):779-90. PubMed ID: 11514227
[TBL] [Abstract][Full Text] [Related]
5. Creating lipoxygenases with new positional specificities by site-directed mutagenesis.
Hornung E; Rosahl S; Kühn H; Feussner I
Biochem Soc Trans; 2000 Dec; 28(6):825-6. PubMed ID: 11171221
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.
Schwarz K; Walther M; Anton M; Gerth C; Feussner I; Kuhn H
J Biol Chem; 2001 Jan; 276(1):773-9. PubMed ID: 11027682
[TBL] [Abstract][Full Text] [Related]
7. Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.
Yu Z; Schneider C; Boeglin WE; Brash AR
Biochim Biophys Acta; 2005 Jan; 1686(3):238-47. PubMed ID: 15629692
[TBL] [Abstract][Full Text] [Related]
8. Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation.
Schwarz K; Borngräber S; Anton M; Kuhn H
Biochemistry; 1998 Nov; 37(44):15327-35. PubMed ID: 9799493
[TBL] [Abstract][Full Text] [Related]
9. Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases.
Borngräber S; Kuban RJ; Anton M; Kühn H
J Mol Biol; 1996 Dec; 264(5):1145-53. PubMed ID: 9000636
[TBL] [Abstract][Full Text] [Related]
10. Applicability of the triad concept for the positional specificity of mammalian lipoxygenases.
Vogel R; Jansen C; Roffeis J; Reddanna P; Forsell P; Claesson HE; Kuhn H; Walther M
J Biol Chem; 2010 Feb; 285(8):5369-76. PubMed ID: 20026599
[TBL] [Abstract][Full Text] [Related]
11. Computational analysis of R and S isoforms of 12-lipoxygenases: homology modeling and docking studies.
Aparoy P; Leela T; Reddy RN; Reddanna P
J Mol Graph Model; 2009 Feb; 27(6):744-50. PubMed ID: 19147381
[TBL] [Abstract][Full Text] [Related]
12. Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies.
Chen XS; Funk CD
FASEB J; 1993 May; 7(8):694-701. PubMed ID: 8500694
[TBL] [Abstract][Full Text] [Related]
13. Stereocontrol of arachidonic acid oxygenation by vertebrate lipoxygenases: newly cloned zebrafish lipoxygenase 1 does not follow the Ala-versus-Gly concept.
Jansen C; Hofheinz K; Vogel R; Roffeis J; Anton M; Reddanna P; Kuhn H; Walther M
J Biol Chem; 2011 Oct; 286(43):37804-12. PubMed ID: 21880725
[TBL] [Abstract][Full Text] [Related]
14. Mutagenesis of triad determinants of rat Alox15 alters the specificity of fatty acid and phospholipid oxygenation.
Pekárová M; Kuhn H; Bezáková L; Ufer C; Heydeck D
Arch Biochem Biophys; 2015 Apr; 571():50-7. PubMed ID: 25731857
[TBL] [Abstract][Full Text] [Related]
15. A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression.
Boeglin WE; Kim RB; Brash AR
Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6744-9. PubMed ID: 9618483
[TBL] [Abstract][Full Text] [Related]
16. Enzymic characterization of epidermis-derived 12-lipoxygenase isoenzymes.
Siebert M; Krieg P; Lehmann WD; Marks F; Fürstenberger G
Biochem J; 2001 Apr; 355(Pt 1):97-104. PubMed ID: 11256953
[TBL] [Abstract][Full Text] [Related]
17. Identification of an amino acid determinant of pH regiospecificity in a seed lipoxygenase from Momordica charantia.
Hornung E; Kunze S; Liavonchanka A; Zimmermann G; Kühn D; Fritsche K; Renz A; Kühn H; Feussner I
Phytochemistry; 2008 Nov; 69(16):2774-80. PubMed ID: 18945457
[TBL] [Abstract][Full Text] [Related]
18. Site-directed mutagenesis studies on a putative fifth iron ligand of mouse 8S-lipoxygenase: retention of catalytic activity on mutation of serine-558 to asparagine, histidine, or alanine.
Jisaka M; Boeglin WE; Kim RB; Brash AR
Arch Biochem Biophys; 2001 Feb; 386(2):136-42. PubMed ID: 11368335
[TBL] [Abstract][Full Text] [Related]
19. Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymes.
Bürger F; Krieg P; Marks F; Fürstenberger G
Biochem J; 2000 Jun; 348 Pt 2(Pt 2):329-35. PubMed ID: 10816426
[TBL] [Abstract][Full Text] [Related]
20. Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases.
Watanabe T; Haeggström JZ
Biochem Biophys Res Commun; 1993 May; 192(3):1023-9. PubMed ID: 8507177
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]