BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 16129685)

  • 1. Pitx2a binds to human papillomavirus type 18 E6 protein and inhibits E6-mediated P53 degradation in HeLa cells.
    Wei Q
    J Biol Chem; 2005 Nov; 280(45):37790-7. PubMed ID: 16129685
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.
    Talis AL; Huibregtse JM; Howley PM
    J Biol Chem; 1998 Mar; 273(11):6439-45. PubMed ID: 9497376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Papillomavirus 16 (HPV-16), HPV-18, and HPV-31 E6 Override the Normal Phosphoregulation of E6AP Enzymatic Activity.
    Thatte J; Banks L
    J Virol; 2017 Nov; 91(22):. PubMed ID: 28835500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The stability of the human papillomavirus E6 oncoprotein is E6AP dependent.
    Tomaić V; Pim D; Banks L
    Virology; 2009 Oct; 393(1):7-10. PubMed ID: 19700180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
    Martinez-Zapien D; Ruiz FX; Poirson J; Mitschler A; Ramirez J; Forster A; Cousido-Siah A; Masson M; Vande Pol S; Podjarny A; Travé G; Zanier K
    Nature; 2016 Jan; 529(7587):541-5. PubMed ID: 26789255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD.
    Tomaic V; Pim D; Thomas M; Massimi P; Myers MP; Banks L
    J Virol; 2011 Apr; 85(7):3120-7. PubMed ID: 21228227
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of small molecule human papillomavirus E6 inhibitors.
    Malecka KA; Fera D; Schultz DC; Hodawadekar S; Reichman M; Donover PS; Murphy ME; Marmorstein R
    ACS Chem Biol; 2014 Jul; 9(7):1603-12. PubMed ID: 24854633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.
    Zhou Y; Wei Y; Zhu J; Wang Q; Bao L; Ma Y; Chen Y; Feng D; Zhang A; Sun J; Nallar SC; Shen K; Kalvakolanu DV; Xiao W; Ling B
    PLoS One; 2011; 6(7):e22065. PubMed ID: 21765936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.
    Kao WH; Beaudenon SL; Talis AL; Huibregtse JM; Howley PM
    J Virol; 2000 Jul; 74(14):6408-17. PubMed ID: 10864652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation.
    Conrady MC; Suarez I; Gogl G; Frecot DI; Bonhoure A; Kostmann C; Cousido-Siah A; Mitschler A; Lim J; Masson M; Iftner T; Stubenrauch F; Travé G; Simon C
    J Virol; 2020 Dec; 95(2):. PubMed ID: 33115863
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.
    Kelley ML; Keiger KE; Lee CJ; Huibregtse JM
    J Virol; 2005 Mar; 79(6):3737-47. PubMed ID: 15731267
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.
    Matsumoto Y; Nakagawa S; Yano T; Takizawa S; Nagasaka K; Nakagawa K; Minaguchi T; Wada O; Ooishi H; Matsumoto K; Yasugi T; Kanda T; Huibregtse JM; Taketani Y
    J Med Virol; 2006 Apr; 78(4):501-7. PubMed ID: 16482544
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities.
    Kehmeier E; Rühl H; Voland B; Stöppler MC; Androphy E; Stöppler H
    Virology; 2002 Jul; 299(1):72-87. PubMed ID: 12167343
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Felis catus papillomavirus type-2 E6 binds to E6AP, promotes E6AP/p53 binding and enhances p53 proteasomal degradation.
    Altamura G; Power K; Martano M; Degli Uberti B; Galiero G; De Luca G; Maiolino P; Borzacchiello G
    Sci Rep; 2018 Dec; 8(1):17529. PubMed ID: 30510267
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells.
    Clemente-Soto AF; Salas-Vidal E; Milan-Pacheco C; Sánchez-Carranza JN; Peralta-Zaragoza O; González-Maya L
    Mol Med Rep; 2019 Mar; 19(3):2097-2106. PubMed ID: 30664221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HMGB2 stabilizes p53 by interfering with E6/E6AP-mediated p53 degradation in human papillomavirus-positive HeLa cells.
    Lee D; Kwon JH; Kim EH; Kim ES; Choi KY
    Cancer Lett; 2010 Jun; 292(1):125-32. PubMed ID: 20036050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation.
    Alarcón R; Koumenis C; Geyer RK; Maki CG; Giaccia AJ
    Cancer Res; 1999 Dec; 59(24):6046-51. PubMed ID: 10626788
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.
    Nakagawa S; Huibregtse JM
    Mol Cell Biol; 2000 Nov; 20(21):8244-53. PubMed ID: 11027293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function.
    Cherry JJ; Rietz A; Malinkevich A; Liu Y; Xie M; Bartolowits M; Davisson VJ; Baleja JD; Androphy EJ
    PLoS One; 2013; 8(12):e84506. PubMed ID: 24376816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides.
    Stutz C; Reinz E; Honegger A; Bulkescher J; Schweizer J; Zanier K; Travé G; Lohrey C; Hoppe-Seyler K; Hoppe-Seyler F
    PLoS One; 2015; 10(7):e0132339. PubMed ID: 26151636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.