BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 16134002)

  • 1. The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II.
    Knudsen JF; Carlsson U; Hammarström P; Sokol GH; Cantilena LR
    Inflammation; 2004 Oct; 28(5):285-90. PubMed ID: 16134002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Di Fiore A; Pedone C; D'Ambrosio K; Scozzafava A; De Simone G; Supuran CT
    Bioorg Med Chem Lett; 2006 Jan; 16(2):437-42. PubMed ID: 16290146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
    Weber A; Casini A; Heine A; Kuhn D; Supuran CT; Scozzafava A; Klebe G
    J Med Chem; 2004 Jan; 47(3):550-7. PubMed ID: 14736236
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of the selective cyclooxygenase-2 inhibitor analgesic celecoxib on renal carbonic anhydrase enzyme activity: a randomized, controlled trial.
    Alper AB; Tomlin H; Sadhwani U; Whelton A; Puschett J
    Am J Ther; 2006; 13(3):229-35. PubMed ID: 16772765
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.
    Nocentini A; Moi D; Balboni G; Salvadori S; Onnis V; Supuran CT
    Bioorg Chem; 2018 Apr; 77():633-639. PubMed ID: 29502024
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppression of adjuvant-induced arthritic bone destruction by cyclooxygenase-2 selective agents with and without inhibitory potency against carbonic anhydrase II.
    Katagiri M; Ogasawara T; Hoshi K; Chikazu D; Kimoto A; Noguchi M; Sasamata M; Harada S; Akama H; Tazaki H; Chung UI; Takato T; Nakamura K; Kawaguchi H
    J Bone Miner Res; 2006 Feb; 21(2):219-27. PubMed ID: 16418777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents.
    Supuran CT; Casini A; Mastrolorenzo A; Scozzafava A
    Mini Rev Med Chem; 2004 Aug; 4(6):625-32. PubMed ID: 15279596
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides.
    Mete E; Comez B; Inci Gul H; Gulcin I; Supuran CT
    J Enzyme Inhib Med Chem; 2016; 31(sup2):1-5. PubMed ID: 27435177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.
    Gierse JK; Zhang Y; Hood WF; Walker MC; Trigg JS; Maziasz TJ; Koboldt CM; Muhammad JL; Zweifel BS; Masferrer JL; Isakson PC; Seibert K
    J Pharmacol Exp Ther; 2005 Mar; 312(3):1206-12. PubMed ID: 15494548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual carbonic anhydrase--cyclooxygenase-2 inhibitors.
    Dogné JM; Thiry A; Pratico D; Masereel B; Supuran CT
    Curr Top Med Chem; 2007; 7(9):885-91. PubMed ID: 17504133
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.
    Sethi KK; Vullo D; Verma SM; Tanç M; Carta F; Supuran CT
    Bioorg Med Chem; 2013 Oct; 21(19):5973-82. PubMed ID: 23965175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insight into the inhibition of carbonic anhydrase by the COX-2-selective inhibitor polmacoxib (CG100649).
    Kim HT; Cha H; Hwang KY
    Biochem Biophys Res Commun; 2016 Sep; 478(1):1-6. PubMed ID: 27475498
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition profiling of human carbonic anhydrase II by high-throughput screening of structurally diverse, biologically active compounds.
    Iyer R; Barrese AA; Parakh S; Parker CN; Tripp BC
    J Biomol Screen; 2006 Oct; 11(7):782-91. PubMed ID: 16858005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity?
    Gassani BC; Rezende RM; Paiva-Lima P; Ferreira-Alves DL; dos Reis WG; Bakhle YS; de Francischi JN
    Pharmacol Res; 2010 Nov; 62(5):439-43. PubMed ID: 20600917
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual Cyclooxygenase and Carbonic Anhydrase Inhibition by Nonsteroidal Anti-Inflammatory Drugs for the Treatment of Cancer.
    De Monte C; Carradori S; Gentili A; Mollica A; Trisciuoglio D; Supuran CT
    Curr Med Chem; 2015; 22(24):2812-8. PubMed ID: 26180003
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.
    Khloya P; Ceruso M; Ram S; Supuran CT; Sharma PK
    Bioorg Med Chem Lett; 2015 Aug; 25(16):3208-12. PubMed ID: 26105196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines.
    Kucukoglu K; Oral F; Aydin T; Yamali C; Algul O; Sakagami H; Gulcin I; Supuran CT; Gul HI
    J Enzyme Inhib Med Chem; 2016; 31(sup4):20-24. PubMed ID: 27579806
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
    Gitto R; Agnello S; Ferro S; De Luca L; Vullo D; Brynda J; Mader P; Supuran CT; Chimirri A
    J Med Chem; 2010 Mar; 53(6):2401-8. PubMed ID: 20170095
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.
    Krasavin M; Korsakov M; Dorogov M; Tuccinardi T; Dedeoglu N; Supuran CT
    Eur J Med Chem; 2015 Aug; 101():334-47. PubMed ID: 26160114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A class of sulfonamides as carbonic anhydrase I and II inhibitors.
    Gokcen T; Gulcin I; Ozturk T; Goren AC
    J Enzyme Inhib Med Chem; 2016; 31(sup2):180-188. PubMed ID: 27353698
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.