BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 16134932)

  • 1. Enhancement of aqueous solubility and stability employing a trans acetate axis in trans planar amine platinum compounds while maintaining the biological profile.
    Ma ES; Bates WD; Edmunds A; Kelland LR; Fojo T; Farrell N
    J Med Chem; 2005 Sep; 48(18):5651-4. PubMed ID: 16134932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. trans-Platinum planar amine compounds with [N2O2] ligand donor sets: effects of carboxylate leaving groups and steric hindrance on chemical and biological properties.
    Bulluss GH; Knott KM; Ma ES; Aris SM; Alvarado E; Farrell N
    Inorg Chem; 2006 Jul; 45(15):5733-5. PubMed ID: 16841974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of drug activation profiles through carboxylate ligand modification in cytotoxic trans-platinum planar amine compounds.
    Benedetti BT; Quintal S; Farrell NP
    Dalton Trans; 2011 Nov; 40(41):10983-8. PubMed ID: 21918760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New trans-platinum drugs with phosphines and amines as carrier ligands induce apoptosis in tumor cells resistant to cisplatin.
    Ramos-Lima FJ; Quiroga AG; García-Serrelde B; Blanco F; Carnero A; Navarro-Ranninger C
    J Med Chem; 2007 May; 50(9):2194-9. PubMed ID: 17407274
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Platinum(II) compounds with chelating ligands based on pyridine and pyrimidine: synthesis, characterizations, DFT calculations, cytotoxic assays and binding to a DNA model base.
    Roy S; Westmaas JA; Buda F; Reedijk J
    J Inorg Biochem; 2009 Sep; 103(9):1278-87. PubMed ID: 19656572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, characterization, and in vitro cytotoxicity of some gold(I) and trans platinum(II) thionate complexes containing water-soluble PTA and DAPTA ligands. X-ray crystal structures of [Au(SC4H3N2)(PTA)], trans-[Pt(SC4H3N2)2(PTA)2], trans-[Pt(SC5H4N)2(PTA)2], and trans-[Pt(SC5H4N)2(DAPTA)2].
    Miranda S; Vergara E; Mohr F; de Vos D; Cerrada E; Mendía A; Laguna M
    Inorg Chem; 2008 Jul; 47(13):5641-8. PubMed ID: 18447334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and characterization of platinum(II) oxadiazoline complexes and their in vitro antitumor activity in platinum-sensitive and -resistant cancer cell lines.
    Coley HM; Sarju J; Wagner G
    J Med Chem; 2008 Jan; 51(1):135-41. PubMed ID: 18072719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cisplatinum and transplatinum complexes with benzyliminoether ligands; synthesis, characterization, structure-activity relationships, and in vitro and in vivo antitumor efficacy.
    Sbovata SM; Bettio F; Mozzon M; Bertani R; Venzo A; Benetollo F; Michelin RA; Gandin V; Marzano C
    J Med Chem; 2007 Sep; 50(19):4775-84. PubMed ID: 17713897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new class of antitumor trans-amine-amidine-Pt(II) cationic complexes: influence of chemical structure and solvent on in vitro and in vivo tumor cell proliferation.
    Marzano C; Mazzega Sbovata S; Gandin V; Colavito D; Del Giudice E; Michelin RA; Venzo A; Seraglia R; Benetollo F; Schiavon M; Bertani R
    J Med Chem; 2010 Aug; 53(16):6210-27. PubMed ID: 20681543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reaction of Zn7metallothionein with cis- and trans-[Pt(N-donor)2Cl2] anticancer complexes: trans-Pt(II) complexes retain their N-donor ligands.
    Knipp M; Karotki AV; Chesnov S; Natile G; Sadler PJ; Brabec V; Vasák M
    J Med Chem; 2007 Aug; 50(17):4075-86. PubMed ID: 17665893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.
    Monti E; Gariboldi M; Maiocchi A; Marengo E; Cassino C; Gabano E; Osella D
    J Med Chem; 2005 Feb; 48(3):857-66. PubMed ID: 15689170
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity.
    Peacock AF; Parsons S; Sadler PJ
    J Am Chem Soc; 2007 Mar; 129(11):3348-57. PubMed ID: 17319668
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand.
    Marzano C; Pellei M; Colavito D; Alidori S; Lobbia GG; Gandin V; Tisato F; Santini C
    J Med Chem; 2006 Dec; 49(25):7317-24. PubMed ID: 17149861
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel transplatinum(II) complexes with [N2O2] donor sets. Cellular pharmacology and apoptosis induction in Pam 212-ras cells.
    Quiroga AG; Pérez JM; Alonso C; Navarro-Ranninger C; Farrell N
    J Med Chem; 2006 Jan; 49(1):224-31. PubMed ID: 16392807
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance.
    Margiotta N; Natile G; Capitelli F; Fanizzi FP; Boccarelli A; De Rinaldis P; Giordano D; Coluccia M
    J Inorg Biochem; 2006 Nov; 100(11):1849-57. PubMed ID: 16959321
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
    Zák F; Turánek J; Kroutil A; Sova P; Mistr A; Poulová A; Mikolin P; Zák Z; Kasná A; Záluská D; Neca J; Sindlerová L; Kozubík A
    J Med Chem; 2004 Jan; 47(3):761-3. PubMed ID: 14736257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies.
    Najajreh Y; Khazanov E; Jawbry S; Ardeli-Tzaraf Y; Perez JM; Kasparkova J; Brabec V; Barenholz Y; Gibson D
    J Med Chem; 2006 Jul; 49(15):4665-73. PubMed ID: 16854072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and characterization of platinum(IV) anticancer drugs with functionalized aromatic carboxylate ligands: influence of the ligands on drug efficacies and uptake.
    Ang WH; Pilet S; Scopelliti R; Bussy F; Juillerat-Jeanneret L; Dyson PJ
    J Med Chem; 2005 Dec; 48(25):8060-9. PubMed ID: 16335930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Platinum (II) complexes with stereochemically-defined thiepane dioxide diamine ligands as anticancer drugs.
    Cerè V; Grossi L; Munari D; Pollicino S; Martelli L; Martelli M
    Anticancer Res; 2006; 26(3A):1815-9. PubMed ID: 16827112
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Palladium(II) and platinum(II) organometallic complexes with 4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine. Antitumor activity of the platinum compounds.
    Ruiz J; Villa MD; Cutillas N; López G; de Haro C; Bautista D; Moreno V; Valencia L
    Inorg Chem; 2008 Jun; 47(11):4490-505. PubMed ID: 18447329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.